New Highly Specific SARS-CoV-2 Neutralizing Antibodies Detection Kit
AdipoGen Life Sciences has developed a sensitive, specific and fast SARS-CoV-2 Neutralizing Antibodies Detection Kit (Prod. No. AG-48B-0002) that can be used to detect the presence of neutralizing antibodies against SARS-CoV-2 in serum/plasma in about 2 hours independently of species and isotypes!
This Detection Kit is based on a colorimetric reaction, which measures the binding of the RBD of the Spike S protein from SARS-CoV-2 to its human receptor ACE2. The presence of neutralizing/blocking antibodies in the samples are detected by reduction of signal indicating the inhibition of the Spike-ACE2 binding.
The SARS-CoV-2 Neutralizing Antibodies Detection Kit contains key reagents required to test the presence of functional neutralizing antibodies against SARS-CoV-2 present in the serum or plasma. It is an easy, fast and scalable (automation) alternative to the classical neutralization assays using Vero E6 cells, such as virus neutralization test (VNT) and pseudo-virus neutralization test (pVNT) and does not need biosafety requirements.
Several uses: This kit is administrable in vaccine and therapeutic development as it is suitable for all antibody isotypes and can be used to determine neutralizing antibodies in animal models. The kit will also be useful in current COVID-19 investigations of sero-prevalence, assessment of immune response, herd immunity, longevity of protective immunity, efficacy of different vaccine candidates as well as tracking infections in animals.
High Specificity has been confirmed and published: Comparison of two commercial surrogate ELISAs to detect a neutralizing antibody response to SARS-CoV-2: K. Mueller, et al.; J. Virol. Methods 292, 114122 (2021).
Product Name | PID | Application/Activity |
SARS-CoV-2 Neutralizing Antibodies Detection Kit (B.1.1.7 Variant, Alpha) | AG-48B-0003 | To measure the presence of neutralizing/blocking antibodies in human serum/plasma that inhibit the binding of the SARS-CoV-2 Spike (RBD) (B.1.1.7 Variant, Alpha) protein to its human receptor ACE2. |
SARS-CoV-2 Neutralizing Antibodies Detection Kit (P.1 Variant, Gamma) | AG-48B-0004 | To measure the presence of neutralizing/blocking antibodies in human serum/plasma that inhibit the binding of the SARS-CoV-2 Spike (RBD) (P.1 Variant, Gamma) protein to its human receptor ACE2. |
SARS-CoV-2 Neutralizing Antibodies Detection Kit (B.1.351 Variant, Beta) | AG-48B-0005 | To measure the presence of neutralizing/blocking antibodies in human serum/plasma that inhibit the binding of the SARS-CoV-2 Spike (RBD) (B.1.351 Variant, Beta) protein to its human receptor ACE2. |
SARS-CoV-2 Neutralizing Antibodies Detection Kit (B.1.617.1 Variant, Kappa) | AG-48B-0006 | To measure the presence of neutralizing/blocking antibodies in human serum/plasma that inhibit the binding of the SARS-CoV-2 Spike (RBD) (B.1.617.1 Variant, Kappa) protein to its human receptor ACE2. |
NEW SARS-CoV-2 Neutralizing Antibodies Detection Kit (B.1.617.2 Variant, Delta) |
AG-48B-0007 | To measure the presence of neutralizing/blocking antibodies in human serum/plasma that inhibit the binding of the SARS-CoV-2 Spike (RBD) (B.1.617.2 Variant, Delta) protein to its human receptor ACE2. |
The STANDARD for Initial SARS-CoV-2 Strain SARS-CoV-2 Neutralizing Antibodies Detection Kit |
AG-48B-0002 | To measure the presence of neutralizing/blocking antibodies in human serum/plasma that inhibit the binding of the SARS-CoV-2 Spike (RBD) (initial strain) protein to its human receptor ACE2. |
Besides, use the 25% of descount in this COVID-19 prouducts promotions.
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