pharmacogenetics panels

Reliable and precise detection

• Detect SNPs, indel variations, and CNVs in a single assay.
• Haplotype reports are rapidly generated from genotyping data with automated software tools.
• 96- and 384-well formats offer the flexibility to generate results from 10s to 1000s of samples a day.

Veridose Core Panel

The VeriDose® Core Panel targets the most relevant variants in 20 principle genes implicated in drug metabolism pathways. Veridose Core provides genotype information for 68 SNPs/INDELs across 20 genes, plus 5 copy number detection targets in CYP2D6. The panel is designed to be tolerant to low quality DNA, boosting the likelihood of success with challenging samples.

Veridose CYP2D6 CNV Panel

This panels provides an accurate analisis of thecopy number variation (CNV) of the CYP2D6 gen and detects hybrid allele. Interrogates 7 regions of across the CYP2D6gene. This panel can be combined with genotyping panels using the same workflow.

iPLEX CYP2C9/VKORC1 Panel

This panel allows obtaining biologically relevant data for most of the known haplotypes of the CYP2C9and VKORC1genes. These genes are relevant for the pharmacogenetic study of patients prescribed Warfarin, a drug widely used as an oral anticoagulant. Interrogates 38 SNPs in CYP2C9and 11 SNPs in VKORC1.

iPLEX CYP2C19 Panel

Investigate and confirm pharmacogenetic biomarkers in CYP2C19. The study of polymorphisms in CYP2C19 is relevant for the study of patients Clopidogrel prescribed. The panel contains assays for 31 SNPs, covering most of the known haplotypes.

iPLEX CYP2D6 Panel

The CYP2D6 Panel is a set of 30 SNP and 5 CNV assays, covering most of the known CYP2D6 haplotypes.