Leinco Technologies is a biotechnology company founded in 1992 as a specialist manufacturer of early discovery research products, including antibodies and recombinant proteins. Shortly thereafter, they established themselves as a leading provider of customised R&D and manufacturing services focused on monoclonal antibodies and recombinant proteins.
Leinco Technologies has developed proprietary methods for the manufacture of in vivo functional grade antibodies with the highest purity standards in the industry. In vivo grade antibodies have diverse uses in biological research, from the discovery of cell signalling pathways to the manipulation of biological systems in animal models for pre-clinical studies. Leinco Technologies’ in vivo antibodies have low levels of endotoxins, with no detectable aggregates or leachable Protein A. These antibodies are produced in their cGMP and ISO 9001:2015 / ISO 13485:2015 certified facilities and are available in customised concentrations and pack sizes. PLATINUM in vivo antibodies are also suitable for animal injection as they are pathogen-free as determined by IDEXX Impact I PCR mouse pathogen profiling. Leinco Technologies offers a wide range of purified in vivo antibodies that can be used for flow cytometry, immunohistochemistry, spatial biology studies, etc.
Compare and contrast in vivo GOLD™ versus in vivo PLATINUM™ to see how they measure up to our quality standards:
| In vivo GOLD™ MAbs | In vivo PLATINUM™ MAbs | |
| Binding validation determined by WB, FC or ELISA | Yes | Yes |
| Endotoxin level determined by the LAL method | ≤ 1.0 EU/mg | ≤ 0.5 EU/mg |
| Antibody aggregation screening by analytical SEC | ≥ 95% monomer | ≥ 98% monomer |
| Purity by SDS PAGE | ≥ 95% | ≥ 98% |
| Formulation for in vivo use | No preservatives No stabilizers No carrier protein Sterile PBS pH 7.2 – No K+ or Ca2+ Concentration: > 5mg/mL |
No preservatives No stabilizers No carrier protein Sterile PBS pH 7.2 – No K+ or Ca2+ Concentration: > 5mg/mL |
| Murine pathogen screening | Not applicable, see PLATINUM functional grade antibodies | Pathogen tested (IMPACT1) |
| Applications | In vivo functional studies and may be used for WB, FC, IF or IHC | |
| Product preparation | Functional grade preclinical antibodies are manufactured in an animal free facility using only in vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates. | |
If you need more information or a quote, please do not hesitate to contact us:
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