The inspiration for Visikol began at Rutgers University in the fall of 2012 when Visikol Co-Founder Dr. Tom Villani first developed the Visikol tissue clearing reagents for use with a wide range of tissues. These reagents have been used by hundreds of research groups from all around the world. Visikol offers products that give researchers unprecedented insight into tissues for better characterization. They market various reagents and support materials that allow researchers to label and image tissues in 3D for complete characterization.
A rapid, easy-to-use, affordable and reversible tissue clearing technique for whole tissues. Easily pair fluorescent protein and/or immunofluorescent labeling with tissue clearing for whole tissue (e.g. mouse brain, tumor) imaging using confocal, light sheet or 2-photon microscopy. In the side column you have a video with more information.
A Visikol HISTO reagent designed specifically for use with 3D cell culture models (e.g. organoids, spheroids, microtissues) in high throughput automated assays. The Visikol HISTO-M technology allows for complete 3D cell culture characterization instead of current assays that are biased towards only peripheral characterization.
A tissue clearing technique designed for use with plant samples for microscopic quality control. Visikol for Plant Biology is commonly used as a replacement for Hertwig’s solution which was previously used for this purpose and is a DEA controlled substance.
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Study on whether tissue clearing combined with confocal microscopy allows an increase in the cells detected (C) when compared a 3D cell culture model cleared with Visikol HISTO-M (B) and a 3D cell culture model imaged in PBS without clearing.
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