Category: Immunoassays

Reference: YIF-LF-EK0134
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Myeloperoxidase is a major neutrophil protein and is also present in monocytes. In neutrophils, it is stored in azurophilic granules and released during phagocytosis. It is a heme enzyme that uses the superoxide and...
Reference: YIF-LF-EK0255
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Methione sulfoxide reductase (MsrA) reduces methionine sulfoxide (MetO) residues in proteins and free MetO to Methionine (Met). The catalytic activity of MsrA is dependent of bound metal and cofactors but it requires...
Reference: YIF-LF-EK0256
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Methione sulfoxide reductase (MsrA) reduces methionine sulfoxide (MetO) residues in proteins and free MetO to Methionine (Met). The catalytic activity of MsrA is dependent of bound metal and cofactors but it requires...
Reference: YIF-LF-EK0254
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Methione sulfoxide reductase (MsrA) reduces methionine sulfoxide (MetO) residues in proteins and free MetO to Methionine (Met). The catalytic activity of MsrA is dependent of bound metal and cofactors but it requires...
Reference: AG-45A-0046YTP-KI01
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Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown...
Reference: AG-45A-0046YEK-KI01
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Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown...
Reference: AG-45A-0041YTP-KI01
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IL-37 (IL-1F7; IL-1H4) is an IL-1 family member that is expressed only in certain types of human organs and cells such as heart, thymus, testis, kidney, mononuclear cells (PBMCs) and dendritic cells. IL-37 is an...
Reference: AG-45A-0041YEK-KI01
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IL-37 (IL-1F7; IL-1H4) is an IL-1 family member that is expressed only in certain types of human organs and cells such as heart, thymus, testis, kidney, mononuclear cells (PBMCs) and dendritic cells. IL-37 is an...
Reference: AG-45B-0008-KI01
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IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) are members of the IL-1 cytokine family that bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1 and are inhibited...
Reference: AG-45B-0013-KI01
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IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) are members of the IL-1 cytokine family that bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1 and are inhibited...
Reference: AG-45B-0021-KI01
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The interleukin-1 (IL-1) family is a central mediator of innate immunity and inflammation. IL-1 family members are associated with both the development and progression of inflammatory diseases and have been linked to...
Reference: REV-31-1023-MK-KI01
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The Human IgM Matched Antibody Pairs is specific to Human IgM and has been demonstrated through ELISA. It does not cross-react to IgG from Non-Human Primate species (Rhesus and Cynomologus macaques), or mouse, rat or...
Reference: REV-31-1022-MK-KI01
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The Human IgG4 Matched Antibody Pairs is specific to Human IgG4 and has been demonstrated through ELISA to not recognize (cross) IgG from Non-Human Primate species (Rhesus and Cynomologus macaques), nor does the...
Reference: REV-31-1021-MK-KI01
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The Human IgG3 Matched Antibody Pairs is specific to Human IgG3 and has been demonstrated through ELISA to not recognize (cross) IgG from Non-Human Primate species (Rhesus and Cynomologus macaques), nor does the...
Reference: REV-31-1020-MK-KI01
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The Human IgG2 Matched Antibody Pairs is specific to Human IgG2 and has been demonstrated through ELISA to not recognize (cross) IgG from Non-Human Primate species (Rhesus and Cynomologus macaques), nor does the...
Reference: REV-31-1019-MK-KI01
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The Human IgG1 Matched Antibody Pair recognize Human IgG1 specifically and does not cross-react to IgG from Non-Human Primate species (Rhesus and Cynomologus macaques), or mouse, rat, goat immunoglobulin. This Human...
Reference: REV-31-1024-MK-KI01
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The Human IgE Matched Antibody Pairs is specific to Human IgE and has been demonstrated through ELISA. It does not cross-react to IgG from Non-Human Primate species (Rhesus and Cynomologus macaques), or mouse, rat or...
Reference: REV-31-1025-MK-KI01
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The Human IgD Matched Antibody Pairs is specific to Human IgD and has been demonstrated through ELISA. It does not cross-react to IgG from Non-Human Primate species (Rhesus and Cynomologus macaques), or mouse, rat or...
Reference: REV-31-1030-MK-KI01
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The Human IgA Matched Antibody Pairs is specific to Human IgA and has been demonstrated through ELISA. It does not cross-react to IgG from Non-Human Primate species (Rhesus and Cynomologus macaques), or mouse, rat or...
Reference: AG-45B-0017-KI01
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Inducible T-cell costimulatory protein (ICOS, also called CD278, AILIM, H4), a member of the CD28 family of costimulatory receptors, has a role in the generation and maintenance of germinal centers (GCs) in lymphatic...
Reference: JAI-KHL-700E
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Oxidative damage to lipids (lipid peroxidation) has been found to play an important role in various disease and aging processes. During early stages of lipid peroxidation, lipid hydroperoxides (LOOH) are formed. These...
Reference: YIF-LF-EK0120
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Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antimicrobial; Antioxidant, has antibacterial activity...
Reference: YIF-LF-EK0121
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Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antimicrobial; Antioxidant, has antibacterial activity...
Reference: YIF-LF-EK0119
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Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antimicrobial; Antioxidant, has antibacterial activity...
Reference: YIF-LF-EK0309
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Glutaredoxins are small redox enzymes of approximately one hundred amino-acid residues that use glutathione as a cofactor. Glutaredoxins are oxidized by substrates, and reduced non-enzymatically by glutathione. In...
Reference: AG-45A-0020YTP-KI01
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Glutathione peroxidase 3 (GPX3; GSHPX3) is a selenium-dependent extracellular enzyme, protecting cells and enzymes from oxidative damage by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic...
Reference: AG-45A-0020YEK-KI01
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Glutathione peroxidase 3 (GPX3; GSHPX3) is a selenium-dependent extracellular enzyme, protecting cells and enzymes from oxidative damage by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic...
Reference: AG-45A-0037YTP-KI01
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Glutathione peroxidase 1 (GPX1; cellular glutathione peroxidase), a selenium-dependent antioxidant enzyme, is implicated in the development of cancer and is downregulated in many cancer cells. GPX1-overexpressing mice...
Reference: YIF-LF-EK0111
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Glutathione peroxidases (Gpxs) are ubiquitously expressed proteins which catalyze the reduction of hydrogen peroxides and organic hydroperoxides by glutathione. There are several isoforms which differ in their primary...
Reference: YIF-LF-EK0112
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Glutathione peroxidases (Gpxs) are ubiquitously expressed proteins which catalyze the reduction of hydrogen peroxides and organic hydroperoxides by glutathione. There are several isoforms which differ in their primary...
Reference: YIF-LF-EK0110
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Glutathione peroxidases (Gpxs) are ubiquitously expressed proteins which catalyze the reduction of hydrogen peroxides and organic hydroperoxides by glutathione. There are several isoforms which differ in their primary...
Reference: AG-45A-0037YEK-KI01
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Glutathione peroxidase 1 (GPX1; cellular glutathione peroxidase), a selenium-dependent antioxidant enzyme, is implicated in the development of cancer and is downregulated in many cancer cells. GPX1-overexpressing mice...
Reference: YIF-LF-EK0216
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Glutathione reductase (GR) is a member of pyridine nucleotide-disulfide oxidoreductases, which includes the closely related enzymes thioredoxin reductase, lipoamide dehydrogenase, trypanothione reductase and mercuric...
Reference: YIF-LF-EK0217
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Glutathione reductase (GR) is a member of pyridine nucleotide-disulfide oxidoreductases, which includes the closely related enzymes thioredoxin reductase, lipoamide dehydrogenase, trypanothione reductase and mercuric...
Reference: YIF-LF-EK0215
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Glutathione reductase (GR) is a member of pyridine nucleotide-disulfide oxidoreductases, which includes the closely related enzymes thioredoxin reductase, lipoamide dehydrogenase, trypanothione reductase and mercuric...
Reference: YIF-LF-EK0186
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This enzyme has 2 functions: it catalyzes the production of glutamine and 4-aminobutanoate (gamma-aminobutyric acid, GABA), the latter in a pyridoxal phosphate-independent manner By similarity. Essential for...
Reference: YIF-LF-EK0188
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This enzyme has 2 functions: it catalyzes the production of glutamine and 4-aminobutanoate (gamma-aminobutyric acid, GABA), the latter in a pyridoxal phosphate-independent manner By similarity. Essential for...
Reference: YIF-LF-EK0187
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This enzyme has 2 functions: it catalyzes the production of glutamine and 4-aminobutanoate (gamma-aminobutyric acid, GABA), the latter in a pyridoxal phosphate-independent manner By similarity. Essential for...
Reference: YIF-LF-EK0185
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This enzyme has 2 functions: it catalyzes the production of glutamine and 4-aminobutanoate (gamma-aminobutyric acid, GABA), the latter in a pyridoxal phosphate-independent manner By similarity. Essential for...
Reference: AG-45B-0024-KI01
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Programmed cell death is a key mechanism involved in several biological processes ranging from development and homeostasis to immunity. Apoptosis, pyroptosis and NETosis are three well‐studied modes of cell death....
Reference: AG-45B-0011-KI01
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Inflammasomes are multimeric protein complexes that comprise a sensor (e.g. NLRP3), an adaptor (ASC/Pycard) and the procaspase-1. An inflammasome assembles in response to a diverse range of pathogen-associated or...
Reference: YIF-LF-EK0231
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Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of...
Reference: YIF-LF-EK0232
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Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of...
Reference: YIF-LF-EK0230
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Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of...
Reference: YIF-LF-EK0154
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Fibrinogen has a double function, yielding monomers that polymerize into fibrin and acting as a cofactor in platelet aggregation.
Reference: YIF-LF-EK0156
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Fibrinogen has a double function, yielding monomers that polymerize into fibrin and acting as a cofactor in platelet aggregation.
Reference: YIF-LF-EK0155
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Fibrinogen has a double function, yielding monomers that polymerize into fibrin and acting as a cofactor in platelet aggregation.
Reference: YIF-LF-EK0153
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Fibrinogen has a double function, yielding monomers that polymerize into fibrin and acting as a cofactor in platelet aggregation.
Reference: AG-45B-0022-KI01
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FGL1 (Fibrinogen-like protein 1; also called Hepatocyte-derived fibrinogen-related protein 1; HFREP-1 or Hepassocin) was initially identified as an overexpressed transcript in hepatocyte carcinoma and as a transcript...
Reference: YIF-LF-EK0150
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Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of...
Reference: YIF-LF-EK0152
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Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of...
Reference: YIF-LF-EK0151
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Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of...
Reference: YIF-LF-EK0149
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Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of...
Reference: AG-45B-0014-KI01
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Erythroferrone (also called Myonectin, CTRP15 or Fam13B) is a member of CTRPs (C1q/TNF-related proteins), which are conserved paralogs of adiponectin containing collagen-like and globular C1q-like domains....
Reference: AG-45A-0032YEK-KI01
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The Notch signaling pathway is essential for appropriate cell differentiation and cell fate decisions. DLK1 (Protein delta homolog 1; Preadipocyte factor 1; Pref-1) is a regulator of adipocyte differentiation found in...
Reference: JAI-KDT-010E
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Tyrosine is one of the major targets of protein oxidation. Dityrosine (DT) is known to be formed when tyrosine is damaged by free radicals, such as reactive oxygen species (ROS), metal-catalyzed oxidation, ultraviolet...
Reference: YIF-LF-EK0117
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Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site...
Reference: YIF-LF-EK0118
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Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site...
Reference: YIF-LF-EK0116
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Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site...
Reference: YIF-LF-EK0266
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TNF-related apoptosis-inducing ligand (TRAIL; Apo2L;CD253; TNFSF10) is a type II transmembrane protein of about 34kDa. Like most members of the tumor necrosis factor (TNF) superfamily of cytokines TRAIL can be cleaved...
Reference: YIF-LF-EK0280
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Tumor necrosis factor (TNF)-alpha is an important cytokine in the innate immune response produced by macrophages, neutrophils, fibroblasts, keratinocytes, NK cells, T and B cells, and tumour cells. TNF-alpha mediates...
Reference: YIF-LF-EK0275
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Tumor necrosis factor (TNF)-alpha is an important cytokine in the innate immune response produced by macrophages, neutrophils, fibroblasts, keratinocytes, NK cells, T and B cells, and tumour cells. TNF-alpha mediates...
Reference: YIF-LF-EK0193
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Tumor necrosis factor (TNF)-alpha is an important cytokine in the innate immune response produced by macrophages, neutrophils, fibroblasts, keratinocytes, NK cells, T and B cells, and tumour cells. TNF-alpha mediates...
Reference: YIF-LF-EK0281
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Supports IL-2 independent and IL-4 independent growth of helper T-cells.
Reference: YIF-LF-EK0262
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Interleukin-8 (IL-8) was originally discovered as a neutrophil chemotactic and activating factor and is a member of the alpha (CXC) subfamily of chemokines (including also platelet factor 4, GRO, IP-10, etc.). Many...
Reference: YIF-LF-EK0224
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Interleukin-6 (IL-6) is a pleiotropic alpha-helical cytokine that plays important roles in a central player in the regulation of inflammation, haematopoiesis, immune response and host defense mechanisms. Human IL-6...
Reference: YIF-LF-EK0270
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Interleukin-6 (IL-6) is a pleiotropic alpha-helical cytokine that plays important roles in a central player in the regulation of inflammation, haematopoiesis, immune response and host defense mechanisms. Human IL-6...
Reference: YIF-LF-EK0260
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Interleukin-6 (IL-6) is a pleiotropic alpha-helical cytokine that plays important roles in a central player in the regulation of inflammation, haematopoiesis, immune response and host defense mechanisms. Human IL-6...
Reference: YIF-LF-EK0269
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Factor that induces terminal differentiation of late-developing beta-cells to immunoglobulin secreting cells.
Reference: YIF-LF-EK0259
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Factor that induces terminal differentiation of late-developing beta-cells to immunoglobulin secreting cells.
Reference: YIF-LF-EK0273
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Interleukin-4 (IL-4) is a cytokine produced by type 2 helper T cells, the Th2 cells. These cells tends to make a specific set of lymphokines including IL-4, IL-5, IL-6, IL-10, IL-13, IL-3 and GM-CSF and fail to...
Reference: YIF-LF-EK0268
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Interleukin-4 (IL-4) is a cytokine produced by type 2 helper T cells, the Th2 cells. These cells tends to make a specific set of lymphokines including IL-4, IL-5, IL-6, IL-10, IL-13, IL-3 and GM-CSF and fail to...
Reference: YIF-LF-EK0258
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Interleukin-4 (IL-4) is a cytokine produced by type 2 helper T cells, the Th2 cells. These cells tends to make a specific set of lymphokines including IL-4, IL-5, IL-6, IL-10, IL-13, IL-3 and GM-CSF and fail to...
Reference: YIF-LF-EK0267
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Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes...
Reference: YIF-LF-EK0279
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Interleukin-2 (IL-2) is a 169 amino acid glycoprotein with one intramolecular disulfide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation and maturation of activated T...
Reference: YIF-LF-EK0257
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Interleukin-2 (IL-2) is a 133 amino acid glycoprotein with one intramolecular disulfide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation and maturation of activated T...
Reference: YIF-LF-EK0276
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Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the...
Reference: YIF-LF-EK0282
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The most prominent members of the interleukin-1 (IL-1) superfamily are IL-1alpha and IL-1beta. They lack a signal peptide and are secreted by an unconventional, endoplasmic reticulum-Golgi-independent mechanism....
Reference: YIF-LF-EK0290
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The most prominent members of the interleukin-1 (IL-1) superfamily are IL-1alpha and IL-1beta. They lack a signal peptide and are secreted by an unconventional, endoplasmic reticulum-Golgi-independent mechanism....
Reference: YIF-LF-EK0295
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IL-17 is a cytokine that acts as a potent mediator in delayed-type reactions by increasing chemokine production in various tissues to recruit monocytes and neutrophils to the site of inflammation.
Reference: YIF-LF-EK0299
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Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL-2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses.
Reference: YIF-LF-EK0297
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Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Associates with...
Reference: YIF-LF-EK0271
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Interleukin-12 (IL-12), also known as Natural Killer Cell Stimulatory Factor (NKSF) or Cytotoxic Lymphocyte Maturation Factor (CLMF), is a heterodimeric pleiotropic cytokine made up of a 40 kDa (p40) subunit and a 35...
Reference: YIF-LF-EK0264
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Interleukin-12 (IL-12), also known as Natural Killer Cell Stimulatory Factor (NKSF) or Cytotoxic Lymphocyte Maturation Factor (CLMF), is a heterodimeric pleiotropic cytokine made up of a 40 kDa (p40) subunit and a 35...
Reference: YIF-LF-EK0298
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Interleukin-10 (IL-10) is a cytokine produced by activated Th2 cells, B cells, keratinocytes and monocytes/macrophages. In vitro murine and human IL-10 inhibits cytokine synthesis by Th1 cells, natural killer cells...
Reference: YIF-LF-EK0263
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Interleukin-10 (IL-10) is a cytokine produced by activated Th2 cells, B cells, keratinocytes and monocytes/macrophages. In vitro murine and human IL-10 inhibits cytokine synthesis by Th1 cells, natural killer cells...
Reference: YIF-LF-EK0289
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Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has...
Reference: YIF-LF-EK0288
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Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has...
Reference: YIF-LF-EK0283
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Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes. Monomer. The signaling GM-CSF receptor...
Reference: YIF-LF-EK0294
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Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes...
Reference: YIF-LF-EK0296
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EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal...
Reference: YIF-LF-EK0305
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A small cytokine that belongs to the CC chemokine family. Recruits monocytes, memory T cells, and dendritic cells to the sites of inflammation produced by either tissue injury or infection. Primarily secreted by...
Reference: YIF-LF-EK0303
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IL-17 is a cytokine that acts as a potent mediator in delayed-type reactions by increasing chemokine production in various tissues to recruit monocytes and neutrophils to the site of inflammation. IL-17 is produced by...
Reference: YIF-LF-EK0307
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Lymphotoxin-alpha (LTA; TNF-beta), a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. LTA is highly inducible, secreted, and exists as homotrimeric molecule. LTA forms heterotrimers...
Reference: YIF-LF-EK0308
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Interleukin 15 (IL-15) is a cytokine with structural similarity to IL-2. Like IL-2, IL-15 binds to and signals through a complex composed of IL-2/IL-15 receptor beta chain (CD122) and the common gamma chain (gamma-C,...
Reference: YIF-LF-EK0222
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Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating...
Reference: YIF-LF-EK0223
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Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating...
Reference: YIF-LF-EK0221
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Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating...
Reference: AG-45B-0018-KI01
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CD40 (also called, Tumor necrosis factor receptor superfamily member 5 or TNFRSF5), a transmembrane type I glycoprotein, belongs to the tumor necrosis factor (TNF) gene superfamily and behaves as a co-stimulatory...
Reference: AG-45B-0002-KI01
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Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and interleukin-18 (IL-18) and induces pyroptotic cell death. Caspase-1 is activated by multiprotein...

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