Category: Reagents

Reference: SM32-10
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SB203580 inhibits the IL-2-induced proliferation of primary human T cells, murine CT6 T cells, or BAF F7 B cells with an IC50 of 3 - 5 μM. SB203580 suppresses the development of endometriosis by down-regulating...
Reference: SM32-50
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SB203580 inhibits the IL-2-induced proliferation of primary human T cells, murine CT6 T cells, or BAF F7 B cells with an IC50 of 3 - 5 μM. SB203580 suppresses the development of endometriosis by down-regulating...
Reference: SM32-100
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SB203580 inhibits the IL-2-induced proliferation of primary human T cells, murine CT6 T cells, or BAF F7 B cells with an IC50 of 3 - 5 μM. SB203580 suppresses the development of endometriosis by down-regulating...
Reference: SM90-2
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SB216763 protects both central and peripheral nervous system neurones in culture from death induced by reduced PI 3-kinase pathway activity. Treatment of primary neural progenitor cells with SB216763 resulted in an...
Reference: SM90-10
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SB216763 protects both central and peripheral nervous system neurones in culture from death induced by reduced PI 3-kinase pathway activity. Treatment of primary neural progenitor cells with SB216763 resulted in an...
Reference: SM90-25
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SB216763 protects both central and peripheral nervous system neurones in culture from death induced by reduced PI 3-kinase pathway activity. Treatment of primary neural progenitor cells with SB216763 resulted in an...
Reference: SM90-50
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SB216763 protects both central and peripheral nervous system neurones in culture from death induced by reduced PI 3-kinase pathway activity. Treatment of primary neural progenitor cells with SB216763 resulted in an...
Reference: SM90-200
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SB216763 protects both central and peripheral nervous system neurones in culture from death induced by reduced PI 3-kinase pathway activity. Treatment of primary neural progenitor cells with SB216763 resulted in an...
Reference: SM33-2
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SB431542 suppresses TGF-β-induced proliferation of human osteosarcoma cells. SB431542 treatment of glioma cultures inhibited proliferation, TGF-β-mediated morphologic changes, and cellular motility. Small molecule...
Reference: SM33-10
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SB431542 suppresses TGF-β-induced proliferation of human osteosarcoma cells. SB431542 treatment of glioma cultures inhibited proliferation, TGF-β-mediated morphologic changes, and cellular motility. Small molecule...
Reference: SM33-50
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SB431542 suppresses TGF-β-induced proliferation of human osteosarcoma cells. SB431542 treatment of glioma cultures inhibited proliferation, TGF-β-mediated morphologic changes, and cellular motility. Small molecule...
Reference: SM33-200
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SB431542 suppresses TGF-β-induced proliferation of human osteosarcoma cells. SB431542 treatment of glioma cultures inhibited proliferation, TGF-β-mediated morphologic changes, and cellular motility. Small molecule...
Reference: SM48-1
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In melanoma and colorectal cancer cell lines with B-Raf V600E mutation, an effective inhibition of cell proliferation was achieved by using SB590885 at concentrations that blocked ERK phosphorylation.
Reference: SM48-5
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In melanoma and colorectal cancer cell lines with B-Raf V600E mutation, an effective inhibition of cell proliferation was achieved by using SB590885 at concentrations that blocked ERK phosphorylation.
Reference: SM48-50
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In melanoma and colorectal cancer cell lines with B-Raf V600E mutation, an effective inhibition of cell proliferation was achieved by using SB590885 at concentrations that blocked ERK phosphorylation.
Reference: SM95-10
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Sorafenib has anti-tumor activity in HCC models may be attributed to inhibition of tumor angiogenesis (VEGFR and PDGFR) and direct effects on tumor cell proliferation/survival (Raf kinase signaling-dependent and...
Reference: SM95-50
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Sorafenib has anti-tumor activity in HCC models may be attributed to inhibition of tumor angiogenesis (VEGFR and PDGFR) and direct effects on tumor cell proliferation/survival (Raf kinase signaling-dependent and...
Reference: SM95-500
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Sorafenib has anti-tumor activity in HCC models may be attributed to inhibition of tumor angiogenesis (VEGFR and PDGFR) and direct effects on tumor cell proliferation/survival (Raf kinase signaling-dependent and...
Reference: SM95-1000
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Sorafenib has anti-tumor activity in HCC models may be attributed to inhibition of tumor angiogenesis (VEGFR and PDGFR) and direct effects on tumor cell proliferation/survival (Raf kinase signaling-dependent and...
Reference: SM41-2
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SP600125 blocks the activation and differentiation of primary human CD4 cell cultures. SP600125 has also been shown to prevent apoptosis in an array of cell types, and it inhibits autophagy in HeLa cells.
Reference: SM41-10
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SP600125 blocks the activation and differentiation of primary human CD4 cell cultures. SP600125 has also been shown to prevent apoptosis in an array of cell types, and it inhibits autophagy in HeLa cells.
Reference: SM41-50
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SP600125 blocks the activation and differentiation of primary human CD4 cell cultures. SP600125 has also been shown to prevent apoptosis in an array of cell types, and it inhibits autophagy in HeLa cells.
Reference: SM41-100
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SP600125 blocks the activation and differentiation of primary human CD4 cell cultures. SP600125 has also been shown to prevent apoptosis in an array of cell types, and it inhibits autophagy in HeLa cells.
Reference: SM41-300
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SP600125 blocks the activation and differentiation of primary human CD4 cell cultures. SP600125 has also been shown to prevent apoptosis in an array of cell types, and it inhibits autophagy in HeLa cells.
Reference: SM96-1
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Stauprimide may be used to study the signaling involved in differentiation of ESC. It increased definitive endodermal markers but not markers for visceral/parietal endoderm or mesoderm. Stauprimide-differentiated...
Reference: SM96-5
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Stauprimide may be used to study the signaling involved in differentiation of ESC. It increased definitive endodermal markers but not markers for visceral/parietal endoderm or mesoderm. Stauprimide-differentiated...
Reference: SM96-100
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Stauprimide may be used to study the signaling involved in differentiation of ESC. It increased definitive endodermal markers but not markers for visceral/parietal endoderm or mesoderm. Stauprimide-differentiated...
Reference: SM97-1
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Staurosporine has several effects on cell function, including interruption of cell-cell contacts, decreasing focal contact size, inducing epithelial to mesenchyme transition, and promoting cell differentiation....
Reference: SM97-5
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Staurosporine has several effects on cell function, including interruption of cell-cell contacts, decreasing focal contact size, inducing epithelial to mesenchyme transition, and promoting cell differentiation....
Reference: SM97-10
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Staurosporine has several effects on cell function, including interruption of cell-cell contacts, decreasing focal contact size, inducing epithelial to mesenchyme transition, and promoting cell differentiation....
Reference: SM97-50
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Staurosporine has several effects on cell function, including interruption of cell-cell contacts, decreasing focal contact size, inducing epithelial to mesenchyme transition, and promoting cell differentiation....
Reference: SM98-5
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StemRegenin 1 treatment accelerates the proliferation of CD34+ cells. Sequential co-culture with BMP-4, PGE2, and StemRegenin 1 leads to robust Macaca nemestrina iPSC hematopoietic progenitor cell formation. Culture...
Reference: SM98-25
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StemRegenin 1 treatment accelerates the proliferation of CD34+ cells. Sequential co-culture with BMP-4, PGE2, and StemRegenin 1 leads to robust Macaca nemestrina iPSC hematopoietic progenitor cell formation. Culture...
Reference: SM98-50
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StemRegenin 1 treatment accelerates the proliferation of CD34+ cells. Sequential co-culture with BMP-4, PGE2, and StemRegenin 1 leads to robust Macaca nemestrina iPSC hematopoietic progenitor cell formation. Culture...
Reference: SM98-100
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StemRegenin 1 treatment accelerates the proliferation of CD34+ cells. Sequential co-culture with BMP-4, PGE2, and StemRegenin 1 leads to robust Macaca nemestrina iPSC hematopoietic progenitor cell formation. Culture...
Reference: SM99-1
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SU5402 is used in an embryonic stem cells (ESC) culture method with three inhibitors (3i: SU5402 for FGFR, PD184352 for ERK, and CHIR99021 for GSK3). It has been showed that this 3i method is extremely instrumental in...
Reference: SM99-5
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SU5402 is used in an embryonic stem cells (ESC) culture method with three inhibitors (3i: SU5402 for FGFR, PD184352 for ERK, and CHIR99021 for GSK3). It has been showed that this 3i method is extremely instrumental in...
Reference: SM99-10
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SU5402 is used in an embryonic stem cells (ESC) culture method with three inhibitors (3i: SU5402 for FGFR, PD184352 for ERK, and CHIR99021 for GSK3). It has been showed that this 3i method is extremely instrumental in...
Reference: SM99-50
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SU5402 is used in an embryonic stem cells (ESC) culture method with three inhibitors (3i: SU5402 for FGFR, PD184352 for ERK, and CHIR99021 for GSK3). It has been showed that this 3i method is extremely instrumental in...
Reference: SM100-2
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SU6668 inhibits proliferation of HUVEC and NIH3T3 cells in-vitro and induces >75% growth inhibition against a broad range of tumor types. SU6668 shows antiangiogenic, anti-inflammatory, antimetastatic and proapototic...
Reference: SM100-10
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SU6668 inhibits proliferation of HUVEC and NIH3T3 cells in-vitro and induces >75% growth inhibition against a broad range of tumor types. SU6668 shows antiangiogenic, anti-inflammatory, antimetastatic and proapototic...
Reference: SM100-50
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SU6668 inhibits proliferation of HUVEC and NIH3T3 cells in-vitro and induces >75% growth inhibition against a broad range of tumor types. SU6668 shows antiangiogenic, anti-inflammatory, antimetastatic and proapototic...
Reference: SM100-200
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SU6668 inhibits proliferation of HUVEC and NIH3T3 cells in-vitro and induces >75% growth inhibition against a broad range of tumor types. SU6668 shows antiangiogenic, anti-inflammatory, antimetastatic and proapototic...
Reference: SM101-10
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Sunitinib has been shown to impinge on the osteoblast differentiation process in-vitro. It exhibits antiangiogenic and antitumor activity in multiple xenograft models.
Reference: SM101-50
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Sunitinib has been shown to impinge on the osteoblast differentiation process in-vitro. It exhibits antiangiogenic and antitumor activity in multiple xenograft models.
Reference: SM101-300
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Sunitinib has been shown to impinge on the osteoblast differentiation process in-vitro. It exhibits antiangiogenic and antitumor activity in multiple xenograft models.
Reference: SM101-500
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Sunitinib has been shown to impinge on the osteoblast differentiation process in-vitro. It exhibits antiangiogenic and antitumor activity in multiple xenograft models.
Reference: SM101-1000
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Sunitinib has been shown to impinge on the osteoblast differentiation process in-vitro. It exhibits antiangiogenic and antitumor activity in multiple xenograft models.
Reference: SM102-10
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Tandutinib inhibits cellular proliferation and induces apoptosis. Tandutinib works as a stem-like cells targeted agent to increase efficiency of anticancer drugs and it has antineoplastic activity.
Reference: SM102-50
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Tandutinib inhibits cellular proliferation and induces apoptosis. Tandutinib works as a stem-like cells targeted agent to increase efficiency of anticancer drugs and it has antineoplastic activity.
Reference: SM102-100
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Tandutinib inhibits cellular proliferation and induces apoptosis. Tandutinib works as a stem-like cells targeted agent to increase efficiency of anticancer drugs and it has antineoplastic activity.
Reference: SM103-1
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TG101348 exhibits promising pharmacokinetic profiles. TG101348 inhibits erythropoiesis from induced pluripotent stem cells (iPSC), but has less inhibitory effect on the self-renewal of CD34+ hematopoietic progenitors.
Reference: SM103-5
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TG101348 exhibits promising pharmacokinetic profiles. TG101348 inhibits erythropoiesis from induced pluripotent stem cells (iPSC), but has less inhibitory effect on the self-renewal of CD34+ hematopoietic progenitors.
Reference: SM103-10
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TG101348 exhibits promising pharmacokinetic profiles. TG101348 inhibits erythropoiesis from induced pluripotent stem cells (iPSC), but has less inhibitory effect on the self-renewal of CD34+ hematopoietic progenitors.
Reference: SM103-50
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TG101348 exhibits promising pharmacokinetic profiles. TG101348 inhibits erythropoiesis from induced pluripotent stem cells (iPSC), but has less inhibitory effect on the self-renewal of CD34+ hematopoietic progenitors.
Reference: SM35-2
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Thiazovivin protects human embryonic stem cells (hESC) in the absence of ECM by regulating E-cadherin mediated cell-cell interaction. Thiazovivin also promotes single cell passage of human pluripotent cells.
Reference: SM35-10
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Thiazovivin protects human embryonic stem cells (hESC) in the absence of ECM by regulating E-cadherin mediated cell-cell interaction. Thiazovivin also promotes single cell passage of human pluripotent cells.
Reference: SM35-50
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Thiazovivin protects human embryonic stem cells (hESC) in the absence of ECM by regulating E-cadherin mediated cell-cell interaction. Thiazovivin also promotes single cell passage of human pluripotent cells.
Reference: SM36-1
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HDAC is overexpressed in a variety of cancers and is closely correlated with oncogenic factors.
Reference: SM36-5
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HDAC is overexpressed in a variety of cancers and is closely correlated with oncogenic factors.
Reference: SM36-25
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HDAC is overexpressed in a variety of cancers and is closely correlated with oncogenic factors.
Reference: SM105-2
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TWS119 induces neuronal differentiation in pluripotent murine embryonal carcinoma cells and embryonic stem cells (ESC). Because neuronal differentiation can be achieved without embryoid bodies (EB) formation and RA...
Reference: SM105-10
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TWS119 induces neuronal differentiation in pluripotent murine embryonal carcinoma cells and embryonic stem cells (ESC). Because neuronal differentiation can be achieved without embryoid bodies (EB) formation and RA...
Reference: SM105-25
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TWS119 induces neuronal differentiation in pluripotent murine embryonal carcinoma cells and embryonic stem cells (ESC). Because neuronal differentiation can be achieved without embryoid bodies (EB) formation and RA...
Reference: SM105-50
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TWS119 induces neuronal differentiation in pluripotent murine embryonal carcinoma cells and embryonic stem cells (ESC). Because neuronal differentiation can be achieved without embryoid bodies (EB) formation and RA...
Reference: SM106-5
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Inhibition of MEK/ERK activity by specific MEK inhibitors PD98059 and U0126 rapidly causes the loss of human embryonic stem cells (hESC) pluripotency, acting as a promoter of hESC differentiation. U0126 is also useful...
Reference: SM106-25
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Inhibition of MEK/ERK activity by specific MEK inhibitors PD98059 and U0126 rapidly causes the loss of human embryonic stem cells (hESC) pluripotency, acting as a promoter of hESC differentiation. U0126 is also useful...
Reference: SM106-100
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Inhibition of MEK/ERK activity by specific MEK inhibitors PD98059 and U0126 rapidly causes the loss of human embryonic stem cells (hESC) pluripotency, acting as a promoter of hESC differentiation. U0126 is also useful...
Reference: SM106-300
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Inhibition of MEK/ERK activity by specific MEK inhibitors PD98059 and U0126 rapidly causes the loss of human embryonic stem cells (hESC) pluripotency, acting as a promoter of hESC differentiation. U0126 is also useful...
Reference: SM107-2
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Vandetanib has been shown to influence in the osteoblast differentiation process in-vitro.
Reference: SM107-25
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Vandetanib has been shown to influence in the osteoblast differentiation process in-vitro.
Reference: SM107-100
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Vandetanib has been shown to influence in the osteoblast differentiation process in-vitro.
Reference: SM107-500
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Vandetanib has been shown to influence in the osteoblast differentiation process in-vitro.
Reference: SM16-1
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WH-4-023 in combination with other small molecules supports the self-renewal of naive human embryonic stem cells and maintenance of ground state pluripotency.
Reference: SM16-5
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WH-4-023 in combination with other small molecules supports the self-renewal of naive human embryonic stem cells and maintenance of ground state pluripotency.
Reference: SM16-25
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WH-4-023 in combination with other small molecules supports the self-renewal of naive human embryonic stem cells and maintenance of ground state pluripotency.
Reference: SM16-50
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WH-4-023 in combination with other small molecules supports the self-renewal of naive human embryonic stem cells and maintenance of ground state pluripotency.
Reference: SM16-100
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WH-4-023 in combination with other small molecules supports the self-renewal of naive human embryonic stem cells and maintenance of ground state pluripotency.
Reference: SM16-500
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WH-4-023 in combination with other small molecules supports the self-renewal of naive human embryonic stem cells and maintenance of ground state pluripotency.
Reference: SM38-2
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XAV939 inhibits growth of DLD-1 cells, an APC-deficient colorectal cancer cell line.
Reference: SM38-10
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XAV939 inhibits growth of DLD-1 cells, an APC-deficient colorectal cancer cell line.
Reference: SM38-50
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XAV939 inhibits growth of DLD-1 cells, an APC-deficient colorectal cancer cell line.
Reference: SM38-200
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XAV939 inhibits growth of DLD-1 cells, an APC-deficient colorectal cancer cell line.
Reference: SM02-1
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Y-27632 increases the cloning efficiency of human embryonic stem cells (hESC). Enables the long term expansion of embryonic stem cells (ESC) with single cell passage. hESC treated with Y-27632 in a serum-free medium...
Reference: SM02-5
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Y-27632 increases the cloning efficiency of human embryonic stem cells (hESC). Enables the long term expansion of embryonic stem cells (ESC) with single cell passage. hESC treated with Y-27632 in a serum-free medium...
Reference: SM02-10
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Y-27632 increases the cloning efficiency of human embryonic stem cells (hESC). Enables the long term expansion of embryonic stem cells (ESC) with single cell passage. hESC treated with Y-27632 in a serum-free medium...
Reference: SM02-100
€0.00 (tax incl.)
Y-27632 increases the cloning efficiency of human embryonic stem cells (hESC). Enables the long term expansion of embryonic stem cells (ESC) with single cell passage. hESC treated with Y-27632 in a serum-free medium...
Reference: 073-70 800277
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Aprotinin is a polypeptide extracted from bovine lung and composed of 58 amino acids with a molecular weight of 6’512 Daltons. Aprotinin is a polyvalent reversible inhibitor of serine proteinases including plasmin...
Reference: 399-01
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C8H10FNO2S · HCl Pefabloc® SC is an irreversible proteinase inhibitor with broad specificity for serine proteinases.
Reference: 099-01
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H-Gly-Pro-Arg-Pro-OH · AcOH Pefabloc® FG binds with a high affinity to fibrinogen, inhibits fibrin polymerization, modifies the mechanical properties of fibrin clots and can dissociate non-stabilized fibrin gels.
Reference: 381-01
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C27H31O4N5S · AcOH Nα-(2-Naphthylsulfonylglycyl)-4-amidino-(D,L)-phenylalanine piperidide · AcOH Pefabloc® TH (NAPAP) is one of the most potent and selective competitive inhibitors of thrombin.
Reference: 126-10
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Hirudin is the most potent and specific thrombin inhibitor known. It forms a stable equimolar complex with thrombin. The complete structure of hirudin has been elucidated [Dodt et al., 1984] and a gene coding for...
Reference: 069-03
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Prionex® is a 10% aqueous solution of a polypeptide fraction of highly purified dermal collagen of porcine origin which has excellent protein stabilizing properties. Prionex® is prepared by partial hydrolysis and is...
Reference: 801682
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Rabbit brain cephalin consists of phospholipids isolated from rabbit brain. It can be used as a phospholipid source in phospholipid dependent coagulation assays. The main components are: • Phosphatidylserine •...
Reference: 101-04 101-06
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Defibrase® is the trademark registered by Pentapharm for its Active Pharmaceutical Ingredient (API) Batroxobin, a serine protease. Batroxobin is a thrombin-like enzyme purified from the snake venom of Bothrops...
Reference: 113-01 113-05
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Protac®, a single chain glycoprotein, is a fast-acting protein C activator isolated from the venom of the copperhead snake Agkistrodon contortrix and closely related snake species. This serine proteinase rapidly...
Reference: 116-01
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Ecarin is a 55’000 to 60’000 Da metalloprotease isolated from the venom of the saw-scaled viper (Echis carinatus) that activates prothrombin. Ecarin does not affect other clotting factors. The action of ecarin on...
Reference: 119-02
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Convulxin, a 84'000 Da heterodimeric C-type lectin isolated from Crotalus durissus terrificus venom, activates mammalian platelets via binding and clustering of GPVI-receptors under physiological conditions....
Reference: 121-06 121-07
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Specific 120’000 Da factor X activator from Russell’s viper venom. RVV-X is a dimer of two peptide chains with a molecular weight of 60’000 g/mol each. Activation of factor X by RVV-X strictly depends on the presence...

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