Category: Reagents

Reference: AG-CR1-0162-M005
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Analog of the anticancer drug sorafenib. PK150 is a potent antibiotic. It shows oral bioavailability and antibacterial activity against several pathogenic strains at submicromolar concentrations. PK150 inhibits...
Reference: AG-CR1-0162-M025
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Analog of the anticancer drug sorafenib. PK150 is a potent antibiotic. It shows oral bioavailability and antibacterial activity against several pathogenic strains at submicromolar concentrations. PK150 inhibits...
Reference: AG-CR1-0163-M001
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MAC-545496 is a potent antimicrobial agent against MRSA. It works as a synthetic antibiotic adjuvant, a antivirulence and antibiofilm agent. Potent nanomolar inhibitor of glycopeptide-resistance-associated protein R...
Reference: AG-CR1-0163-M005
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MAC-545496 is a potent antimicrobial agent against MRSA. It works as a synthetic antibiotic adjuvant, a antivirulence and antibiofilm agent. Potent nanomolar inhibitor of glycopeptide-resistance-associated protein R...
Reference: AG-CR1-0163-M025
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MAC-545496 is a potent antimicrobial agent against MRSA. It works as a synthetic antibiotic adjuvant, a antivirulence and antibiofilm agent. Potent nanomolar inhibitor of glycopeptide-resistance-associated protein R...
Reference: AG-CR1-3611-M025
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Anti-inflammatory and anti-arthritic agent. Represses the activation of the NLRP3/IL-1beta pathway. Inhibitor of 5-lipoxygenase in human neutrophils, IKB kinase (IKK) by modifying Cys-179 of the IKKbeta subunit 5....
Reference: AG-CR1-3611-M100
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Anti-inflammatory and anti-arthritic agent. Represses the activation of the NLRP3/IL-1beta pathway. Inhibitor of 5-lipoxygenase in human neutrophils, IKB kinase (IKK) by modifying Cys-179 of the IKKbeta subunit 5....
Reference: BVT-0001-C100
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Antibiotic. Potent endothelin receptor antagonist. Anti-osteoporotic. Antibacterial. Cytotoxic. Mediates its cytotoxic effects, at least in part, through proteasome inhibition.
Reference: BVT-0001-C500
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Antibiotic. Potent endothelin receptor antagonist. Anti-osteoporotic. Antibacterial. Cytotoxic. Mediates its cytotoxic effects, at least in part, through proteasome inhibition.
Reference: BVT-0003-M001
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Antibiotic. Chitin synthase, monoamine oxidase and IgE production inhibitor. Cytotoxic. Shows nematicidal and antileishmanial activity. Antiproliferative against four different glioma cells. Downregulates the...
Reference: BVT-0003-M005
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Antibiotic. Chitin synthase, monoamine oxidase and IgE production inhibitor. Cytotoxic. Shows nematicidal and antileishmanial activity. Antiproliferative against four different glioma cells. Downregulates the...
Reference: BVT-0004-C100
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Macrolide antibiotic. Specific vacuolar-type H+-ATPase inhibitor. Inhibitor of autophagic degradation by rising lysosomal pH and thus inactivating the lysosomal acid hydrolases. Antitrypanosomal and antileishmanial...
Reference: BVT-0004-M001
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Macrolide antibiotic. Specific vacuolar-type H+-ATPase inhibitor. Inhibitor of autophagic degradation by rising lysosomal pH and thus inactivating the lysosomal acid hydrolases. Antitrypanosomal and antileishmanial...
Reference: BVT-0004-M005
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Macrolide antibiotic. Specific vacuolar-type H+-ATPase inhibitor. Inhibitor of autophagic degradation by rising lysosomal pH and thus inactivating the lysosomal acid hydrolases. Antitrypanosomal and antileishmanial...
Reference: BVT-0005-M005
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Antibiotic Antitumor compound. Topoisomerase II inhibitor. Induces single-strand scission in DNA in the presence of reducing agents. Apoptosis inducer. Inhibitor of glioblastoma multiforme (GBM).
Reference: BVT-0006-M001
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Antibiotic. Cell cycle inhibitor at the G(2)/M phase. Antitumor compound. Apoptosis inducer.
Reference: BVT-0006-M005
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Antibiotic. Cell cycle inhibitor at the G(2)/M phase. Antitumor compound. Apoptosis inducer.
Reference: BVT-0007-M001
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Antibiotic. HIV-1 reverse transcriptase and human telomerase inhibitor. Antibacterial. Cytostatically active against different tumor cell lines.
Reference: BVT-0007-M005
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Antibiotic. HIV-1 reverse transcriptase and human telomerase inhibitor. Antibacterial. Cytostatically active against different tumor cell lines.
Reference: BVT-0011-C250
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Antibiotic. Cyclic adenosine 3',5'-monophosphate phosphodiesterase and topoisomerase I (Topo I) inhibitor. Antitumor compound.
Reference: BVT-0011-M001
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Antibiotic. Cyclic adenosine 3',5'-monophosphate phosphodiesterase and topoisomerase I (Topo I) inhibitor. Antitumor compound.
Reference: BVT-0013-C250
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Antibiotic. Antifungal. Topoisomerase II (Topo II) inhibitor. Mg2+- and Zn2+-dependent DNA binding agent. Potent anticancer compound.
Reference: BVT-0013-M001
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Antibiotic. Antifungal. Topoisomerase II (Topo II) inhibitor. Mg2+- and Zn2+-dependent DNA binding agent. Potent anticancer compound.
Reference: BVT-0019-M010
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Mycotoxin. Chelation agent with polyfunctional skeleton for development of biologically active compounds. Moderate antibacterial agent. Tyrosinase inhibitor. Inhibits catecholase activity of tyrosinase....
Reference: BVT-0023-M001
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Antibiotic. Antibacterial. Stereoisomer of SNA 8073B which is a prolyl endopeptidase (PEP) inhibitor. Vincristine-induced cytotoxicity potentiating activity against multi-drug-resistant tumor cells.
Reference: BVT-0024-M001
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Antibiotic. Antibacterial. Antitumor compound.
Reference: BVT-0026-M001
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Angucyclinone antibiotic. Antibacterial and antitumor agent. Potentiates the cytotoxicity of vincristine. Antimalarial agent.
Reference: BVT-0028-M001
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Antibiotic. Antitumor compound. Cytotoxic.
Reference: BVT-0028-M005
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Antibiotic. Antitumor compound. Cytotoxic.
Reference: BVT-0029-M001
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Antibiotic. Shows nematicidal, insecticidal, antibacterial and antifungal activity. Related to asperlactone and aspinonene.
Reference: BVT-0029-M005
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Antibiotic. Shows nematicidal, insecticidal, antibacterial and antifungal activity. Related to asperlactone and aspinonene.
Reference: BVT-0030-M001
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Nucleoside antibiotic. Antitumor compound. Xanthosine monophosphate (XMP) aminase inhibitor. RNA synthesis inhibitor. Specific GMP synthase inhibitor. Reduces intracellular GTP levels.
Reference: BVT-0030-M005
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Nucleoside antibiotic. Antitumor compound. Xanthosine monophosphate (XMP) aminase inhibitor. RNA synthesis inhibitor. Specific GMP synthase inhibitor. Reduces intracellular GTP levels.
Reference: BVT-0031-M001
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Nucleoside antibiotic (amicetin group). Anticoccidial agent. Shows broad antibacterial activity.
Reference: BVT-0033-M001
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Tetracyclic quinone glycoside. Antibacterial and antimalarial. Antitumor compound.
Reference: BVT-0035-M001
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Multifunctional fungal secondary metabolite. Related to aspyrone (Prod. No. BVT-0029).
Reference: BVT-0036-M001
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Antibacterial (Gram-positive and mycobacteria). RNA polymerase inhibitor. Apoptosis inducer.
Reference: BVT-0037-C500
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Antibiotic. Glycopeptide synthesis inhibitor. Antibacterial, antifungal and anticoccidial. Cytotoxic.
Reference: BVT-0037-M001
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Antibiotic. Glycopeptide synthesis inhibitor. Antibacterial, antifungal and anticoccidial. Cytotoxic.
Reference: BVT-0037-M005
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Antibiotic. Glycopeptide synthesis inhibitor. Antibacterial, antifungal and anticoccidial. Cytotoxic.
Reference: BVT-0064-M001
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Antibiotic. SecA inhibitor. Antibacterial and antifungal. Cytotoxic. Methyl analog of equisetin.
Reference: BVT-0064-M005
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Antibiotic. SecA inhibitor. Antibacterial and antifungal. Cytotoxic. Methyl analog of equisetin.
Reference: BVT-0065-M001
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Antibiotic. Antibacterial and antifungal. Antitumor compound. Germination inhibitor.
Reference: BVT-0066-M001
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Spirobisnaphthalene derivative (unpublished). Oxidation product of palmarumycin C3. This compound has not yet been thoroughly tested for its biological activity.
Reference: BVT-0067-C250
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Antifungal. Cytotoxic against some tumor cell lines, partly attributed to inhibition of Ras-inducible genes. Inhibits proliferation of mouse and human T cells. Modulates production of cytokines during T cell...
Reference: BVT-0067-M001
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Antifungal. Cytotoxic against some tumor cell lines, partly attributed to inhibition of Ras-inducible genes. Inhibits proliferation of mouse and human T cells. Modulates production of cytokines during T cell...
Reference: BVT-0068-M001
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Antibiotic. Specific vacuolar-type H+-ATPase inhibitor. Inhibitor of autophagic degradation by rising lysosomal pH and thus inactivating the lysosomal acid hydrolases. Antibacterial, antifungal, insecticidal and...
Reference: BVT-0070-M001
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Antibiotic. Antibacterial. Phytotoxic.
Reference: BVT-0078-M001
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Rasfarnesyltransferase inhibitor. Antifungal, antibacterial and herbicidal. Structurally unique natural products. The basic structure of palmarumycin C1 can be modified by a number of hydroxylation, oxygenation,...
Reference: BVT-0078-M005
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Rasfarnesyltransferase inhibitor. Antifungal, antibacterial and herbicidal. Structurally unique natural products. The basic structure of palmarumycin C1 can be modified by a number of hydroxylation, oxygenation,...
Reference: BVT-0079-C500
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Poly(ADP-ribose) polymerase (PARP) inhibitor.
Reference: BVT-0079-M001
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Poly(ADP-ribose) polymerase (PARP) inhibitor.
Reference: BVT-0080-M001
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Cytostatic. Cytotoxic (3-10 µM).
Reference: BVT-0089-M005
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Antibiotic. Antitumor compound. Cytotoxic. Apoptosis inducer. RNA synthesis inhibitor. DNA intercalating agent. Mcl-1 expression inhibitor p53 pathway activator.
Reference: BVT-0089-M025
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Antibiotic. Antitumor compound. Cytotoxic. Apoptosis inducer. RNA synthesis inhibitor. DNA intercalating agent. Mcl-1 expression inhibitor p53 pathway activator.
Reference: BVT-0090-M001
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Ergot alkaloid. Mycotoxin.
Reference: BVT-0090-M005
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Ergot alkaloid. Mycotoxin.
Reference: BVT-0091-M001
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Antibiotic. Apoptosis and endoplasmic reticulum stress-mediated cell death inducer. Potent, selective and competitive cell permeable rasfarnesyltransferase inhibitor (IC50 = 30 nM). Does not affect...
Reference: BVT-0091-M005
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Antibiotic. Apoptosis and endoplasmic reticulum stress-mediated cell death inducer. Potent, selective and competitive cell permeable rasfarnesyltransferase inhibitor (IC50 = 30 nM). Does not affect...
Reference: BVT-0091-M010
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Antibiotic. Apoptosis and endoplasmic reticulum stress-mediated cell death inducer. Potent, selective and competitive cell permeable rasfarnesyltransferase inhibitor (IC50 = 30 nM). Does not affect...
Reference: BVT-0092-M001
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Antibiotic. Cytochalasan analog with anti-fungal activity. Phytotoxic, nematicidal and anti-bacterial activity. Exhibits cytotoxic effects against human cancer cell lines. Induces apoptosis in lymphocytic leukemia...
Reference: BVT-0092-M005
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Antibiotic. Cytochalasan analog with anti-fungal activity. Phytotoxic, nematicidal and anti-bacterial activity. Exhibits cytotoxic effects against human cancer cell lines. Induces apoptosis in lymphocytic leukemia...
Reference: BVT-0095-M001
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Antibiotic. Shows weak cytotoxic activity against different tumor cell lines. Shows antiparasitic activity.
Reference: BVT-0097-M001
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Phytotoxin. Microtubule assembly inhibitor. Similar to curvularin.
Reference: BVT-0098-C500
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Macrolide antibiotic. Bacterial, protozoan and mammalian threonyl-tRNA synthetase (THrRS) inhibitor. Antiangiogenic (IC50 = 0.8 nM) and anticancer agent. Induces the collapse of formed capillary tubes in a...
Reference: BVT-0098-M001
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Macrolide antibiotic. Bacterial, protozoan and mammalian threonyl-tRNA synthetase (THrRS) inhibitor. Antiangiogenic (IC50 = 0.8 nM) and anticancer agent. Induces the collapse of formed capillary tubes in a...
Reference: BVT-0098-M005
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Macrolide antibiotic. Bacterial, protozoan and mammalian threonyl-tRNA synthetase (THrRS) inhibitor. Antiangiogenic (IC50 = 0.8 nM) and anticancer agent. Induces the collapse of formed capillary tubes in a...
Reference: BVT-0099-C250
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Antibiotic. Topoisomerase II inhibitor. Mediates a unique cross-linking reaction between DNA and histidine H3. Anti-neoplastic. Photosensitizing compound. Antitumor compound against human cell lines.
Reference: BVT-0099-M001
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Antibiotic. Topoisomerase II inhibitor. Mediates a unique cross-linking reaction between DNA and histidine H3. Anti-neoplastic. Photosensitizing compound. Antitumor compound against human cell lines.
Reference: BVT-0100-C250
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Antibiotic. Topoisomerase II inhibitor. Mediates a unique cross-linking reaction between DNA and histidine H3. Anti-neoplastic. Photosensitizing compound. Antitumor compound against human cell lines. Less potent than...
Reference: BVT-0100-M001
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Antibiotic. Topoisomerase II inhibitor. Mediates a unique cross-linking reaction between DNA and histidine H3. Anti-neoplastic. Photosensitizing compound. Antitumor compound against human cell lines. Less potent than...
Reference: BVT-0107-C500
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Antibiotic. Peptide lactone. Antibacterial agent (selective). Potent narrow-spectrum antibiotic against coryneform actinomycetes (MIC value 88 pM). Quorum sensing modulator. Shows hormonal activity. Inducer of...
Reference: BVT-0107-M001
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Antibiotic. Peptide lactone. Antibacterial agent (selective). Potent narrow-spectrum antibiotic against coryneform actinomycetes (MIC value 88 pM). Quorum sensing modulator. Shows hormonal activity. Inducer of...
Reference: BVT-0112-M001
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Polyhydroxylated piperidine alkaloid. alpha-Glucosidase I and II inhibitor. Antidiabetic. Antihyperglycaemic activity. Animal feedstuff additive. Antiviral. Shows anti-HIV activity.
Reference: BVT-0112-M005
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Polyhydroxylated piperidine alkaloid. alpha-Glucosidase I and II inhibitor. Antidiabetic. Antihyperglycaemic activity. Animal feedstuff additive. Antiviral. Shows anti-HIV activity.
Reference: BVT-0130-M001
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alpha-Glucosidase inhibitor. Inhibitor of glycoprotein processing. Strong glycosyltransferase (GTF) inhibitor. Angiogenesis inhibitor. Reduces the size of myocardial infarcts.
Reference: BVT-0139-C250
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Antibiotic. Weak topoisomerase I (Topo I) inhibitor. Structurally similar to staurosporine. Does not show any inhibitory activity against protein kinases. Shows significant antitumor properties in vitro (IC50 = 480 nM...
Reference: BVT-0139-M001
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Antibiotic. Weak topoisomerase I (Topo I) inhibitor. Structurally similar to staurosporine. Does not show any inhibitory activity against protein kinases. Shows significant antitumor properties in vitro (IC50 = 480 nM...
Reference: BVT-0150-M001
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Antibiotic. Antibacterial, antifungal and antiprotozoal. Cytotoxic against several tumor cell lines in vitro.
Reference: BVT-0150-M005
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Antibiotic. Antibacterial, antifungal and antiprotozoal. Cytotoxic against several tumor cell lines in vitro.
Reference: BVT-0152-M001
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Antibiotic. Isomeric to thiotropocin. Antibacterial. Active against Gram-positive and Gram-negative bacteria. Antifungal and anti-nematodical. Shows antitumor activity. Cytotoxic against selected mammalian neuronal...
Reference: BVT-0152-M005
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Antibiotic. Isomeric to thiotropocin. Antibacterial. Active against Gram-positive and Gram-negative bacteria. Antifungal and anti-nematodical. Shows antitumor activity. Cytotoxic against selected mammalian neuronal...
Reference: BVT-0157-M001
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Antibiotic. Member of the elfermycin group. Antibacterial. Protein biosynthesis inhibitor. Specifically interacts with the bacterial elongation factor EF-Tu and prevents the release of EF-Tu from the bacterial...
Reference: BVT-0157-M005
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Antibiotic. Member of the elfermycin group. Antibacterial. Protein biosynthesis inhibitor. Specifically interacts with the bacterial elongation factor EF-Tu and prevents the release of EF-Tu from the bacterial...
Reference: BVT-0158-M001
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Derivative of the farnesyltransferase inhibitor Manumycin A (Prod. No. BVT-0091 http://www.adipogen.com/bvt-0091/manumycin-a.html ). This compound has not yet been thoroughly tested for its biological activity.
Reference: BVT-0161-M001
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Antibiotic. Inhibitor of HIF-1 formation by disrupting the binding of p300 to both HIF-1alpha and HIF-2alpha. Histone H3K9 methyltransferases G9a and Suv39h inhibitor. Tumor growth inhibitor. Angiogenesis inhibitor....
Reference: BVT-0161-M005
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Antibiotic. Inhibitor of HIF-1 formation by disrupting the binding of p300 to both HIF-1alpha and HIF-2alpha. Histone H3K9 methyltransferases G9a and Suv39h inhibitor. Tumor growth inhibitor. Angiogenesis inhibitor....
Reference: BVT-0169-M001
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Mycotoxin. Intermediate of the biosynthetic pathway to aflatoxin B1. Cytotoxic against human solid tumor cell lines.
Reference: BVT-0169-M005
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Mycotoxin. Intermediate of the biosynthetic pathway to aflatoxin B1. Cytotoxic against human solid tumor cell lines.
Reference: BVT-0171-M001
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Intermediate of the biosynthetic pathway to aflatoxin B1. Mycotoxin. DNA synthesis inhibitor. Anticancer compound. Cytotoxic, carcinogenic and mutagenic. Acyl-CoA:cholesterol acyltransferase 2 (ACAT2) inhibitor. Shown...
Reference: BVT-0171-M005
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Intermediate of the biosynthetic pathway to aflatoxin B1. Mycotoxin. DNA synthesis inhibitor. Anticancer compound. Cytotoxic, carcinogenic and mutagenic. Acyl-CoA:cholesterol acyltransferase 2 (ACAT2) inhibitor. Shown...
Reference: BVT-0185-M001
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Antibiotic. Active against Gram-positive bacteria, protozoa and tumors. Testosterone 5alpha-reductase inhibitor. Nitric oxide synthase (NOS) inhibitor. Immunosuppressive. Enhances the antifungal activity of rapamycin.
Reference: BVT-0189-C250
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Mycotoxin. Cytotoxic. Tremorgenic. Potent and specific inhibitor of the breast cancer resistance protein (BCRP; ABCG2). Reverses multidrug resistance mediated by BCRP and increases cytotoxicity of several anticancer...
Reference: BVT-0189-M001
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Mycotoxin. Cytotoxic. Tremorgenic. Potent and specific inhibitor of the breast cancer resistance protein (BCRP; ABCG2). Reverses multidrug resistance mediated by BCRP and increases cytotoxicity of several anticancer...
Reference: BVT-0190-M001
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Protein transport from ER to Golgi inhibitor. ADP-ribosylation factor (Arf) inhibitor. Cytotoxic. Antibiotic. Antiviral. Apoptosis inducer. Antitumor compound. Intracellular collagen degradation inhibitor Reviews.
Reference: BVT-0193-M001
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Antibacterial. Phytotoxin. Melanogenesis inhibitor by reducing tyrosinase production via extracellular signal-regulated protein kinase (ERK) activation. Keratinocyte and epidermis proliferation inhibitor. Mycotoxin....
Reference: BVT-0193-M005
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Antibacterial. Phytotoxin. Melanogenesis inhibitor by reducing tyrosinase production via extracellular signal-regulated protein kinase (ERK) activation. Keratinocyte and epidermis proliferation inhibitor. Mycotoxin....
Reference: BVT-0193-M010
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Antibacterial. Phytotoxin. Melanogenesis inhibitor by reducing tyrosinase production via extracellular signal-regulated protein kinase (ERK) activation. Keratinocyte and epidermis proliferation inhibitor. Mycotoxin....
Reference: BVT-0196-C100
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Antibiotic. Potent antitumor compound. pp60src tyrosine kinase inhibitor. Inhibits c-mycgene expression in murine lymphoblastoma cells. Inhibits the transforming activity of abl, erbB, fps, src and yes. Binds...
Reference: BVT-0196-C500
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Antibiotic. Potent antitumor compound. pp60src tyrosine kinase inhibitor. Inhibits c-mycgene expression in murine lymphoblastoma cells. Inhibits the transforming activity of abl, erbB, fps, src and yes. Binds...

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