Reagents

Rebaudioside A

Reference: CDX-R0090-G050

€0.00 (tax incl.)

Rebaudioside A is a glucosylated steviol glycoside studied and used as a non-glycemic sweetener. It is one of the predominant steviol glycosides isolated from S. rebaudiana leaves. Rebaudioside A is a...

Rebaudioside A

Reference: CDX-R0090-G025

€0.00 (tax incl.)

Rebaudioside A is a glucosylated steviol glycoside studied and used as a non-glycemic sweetener. It is one of the predominant steviol glycosides isolated from S. rebaudiana leaves. Rebaudioside A is a...

Rebaudioside A

Reference: CDX-R0090-G005

€0.00 (tax incl.)

Rebaudioside A is a glucosylated steviol glycoside studied and used as a non-glycemic sweetener. It is one of the predominant steviol glycosides isolated from S. rebaudiana leaves. Rebaudioside A is a...

L-Methionine

Reference: CDX-M0524-G025

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Essential amino acid involved in various biochemical processes in humans and mammals. Important in angiogenesis, the growth of new blood vessels and supplementation may be beneficial in diseases such as Parkinson's,...

Tetra-O-methylscutellarein

Reference: CDX-M0514-M005

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Tetra-O-methylscutellarein is a bioactive component of Siam weed extract. It exhibits anti-inflammatory activity through inhibition of the NF-kappaB pathway. It suppressed IkappaB kinase complex alpha/beta...

Tetra-O-methylscutellarein

Reference: CDX-M0514-M001

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Tetra-O-methylscutellarein is a bioactive component of Siam weed extract. It exhibits anti-inflammatory activity through inhibition of the NF-kappaB pathway. It suppressed IkappaB kinase complex alpha/beta...

Meranzin hydrate

Reference: CDX-M0513-M001

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Meranzin is a bioactive compound from the Traditional Chinese Medicine (TCM) Chaihu-Shugan-San (CSS). Meranzin exhibits anti-inflammatory, analgesic and antibacterial activity. Meranzin regulates the alpha...

Meranzin

Reference: CDX-M0512-M001

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Meranzin is a bioactive compound from the Traditional Chinese Medicine (TCM) Chaihu-Shugan-San (CSS). Meranzin exhibits anti-inflammatory, analgesic and antibacterial activity. Meranzin regulates the alpha...

L-Ascorbic acid

Reference: CDX-L0054-G500

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L-Ascorbic acid (better known as Vitamin C) is a naturally occurring electron donor and therefore serves as a reducing agent. It is synthesized from glucose in the liver of most mammalian species, excluding humans,...

L-Ascorbic acid

Reference: CDX-L0054-G100

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L-Ascorbic acid (better known as Vitamin C) is a naturally occurring electron donor and therefore serves as a reducing agent. It is synthesized from glucose in the liver of most mammalian species, excluding humans,...

L-Glutamine

Reference: CDX-G0041-G500

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L-Glutamine is an amino acid and is essential in the formation of purine and pyrimidine nucleotides, amino sugars, glutathione, L-glutamate and other amino acids as well as in protein synthesis and glucose production....

L-Glutamine

Reference: CDX-G0041-G100

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L-Glutamine is an amino acid and is essential in the formation of purine and pyrimidine nucleotides, amino sugars, glutathione, L-glutamate and other amino acids as well as in protein synthesis and glucose production....

L-Glutamine

Reference: CDX-G0041-G025

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L-Glutamine is an amino acid and is essential in the formation of purine and pyrimidine nucleotides, amino sugars, glutathione, L-glutamate and other amino acids as well as in protein synthesis and glucose production....

Eicosapentaenoic acid

Reference: CDX-C0465-M500

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Eicosapentaenoic acid (EPA) is one of several omega-3 fatty acids abundantly available in marine organisms. EPA has antioxidant, anti-inflammatory, cardiovascular, anticancer and antiobesity activities. EPA is a...

Eicosapentaenoic acid

Reference: CDX-C0465-M100

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Eicosapentaenoic acid (EPA) is one of several omega-3 fatty acids abundantly available in marine organisms. EPA has antioxidant, anti-inflammatory, cardiovascular, anticancer and antiobesity activities. EPA is a...

(-)-Catechin

Reference: CDX-C0453-M025

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Catechins have wide biological functionality, including antioxidant, anti-inflammatory, antiviral and anticancer activities. Catechins also play a key role in regulating carbohydrate and lipid metabolism. (-)-Catechin...

(-)-Catechin

Reference: CDX-C0453-M005

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Catechins have wide biological functionality, including antioxidant, anti-inflammatory, antiviral and anticancer activities. Catechins also play a key role in regulating carbohydrate and lipid metabolism. (-)-Catechin...

p-Coumaric acid

Reference: CDX-C0400-G025

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p-Coumaric acid is mainly a plant metabolite which exhibits antioxidant, antimicrobial, antitumor, antiangiogenic, antidiabetic, antihyperlipidemic, neuroprotective and anti-inflammatory properties. It shows...

p-Coumaric acid

Reference: CDX-C0400-G010

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p-Coumaric acid is mainly a plant metabolite which exhibits antioxidant, antimicrobial, antitumor, antiangiogenic, antidiabetic, antihyperlipidemic, neuroprotective and anti-inflammatory properties. It shows...

Curcumin

Reference: CDX-C0158-G050

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Curcumin is the major yellow pigment in turmeric and curry and has antioxidant, anti-inflammatory, neuroprotective, cardioprotective, antidiabetic, antiviral, antibacterial, antifungal, chemopreventive and antitumor...

Curcumin

Reference: CDX-C0158-G010

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Curcumin is the major yellow pigment in turmeric and curry and has antioxidant, anti-inflammatory, neuroprotective, cardioprotective, antidiabetic, antiviral, antibacterial, antifungal, chemopreventive and antitumor...

Caffeic acid

Reference: CDX-C0024-G025

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Caffeic Acid is an endogenous phenolic phytochemical compound that inhibits a number of lipoxygenases such as 5-LO (5-lipoxygenase), in a non-competitive manner, and 12-LO (12-lipoxygenase) inhibiting leukotriene...

Caffeic acid

Reference: CDX-C0024-G005

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Caffeic Acid is an endogenous phenolic phytochemical compound that inhibits a number of lipoxygenases such as 5-LO (5-lipoxygenase), in a non-competitive manner, and 12-LO (12-lipoxygenase) inhibiting leukotriene...

Dapansutrile

Reference: AG-CR1-3535-M250

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Dapansutrile is a potent, selective and orally active inhibitor of the NLRP3 inflammasome. It directly binds to the ATP-binding motif of NLRP3 NACHT domain and inhibits NLRP3 adenosine triphosphatase (ATPase)...

Dapansutrile

Reference: AG-CR1-3535-M050

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Dapansutrile is a potent, selective and orally active inhibitor of the NLRP3 inflammasome. It directly binds to the ATP-binding motif of NLRP3 NACHT domain and inhibits NLRP3 adenosine triphosphatase (ATPase)...

Dapansutrile

Reference: AG-CR1-3535-M010

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Dapansutrile is a potent, selective and orally active inhibitor of the NLRP3 inflammasome. It directly binds to the ATP-binding motif of NLRP3 NACHT domain and inhibits NLRP3 adenosine triphosphatase (ATPase)...

Mubritinib

Reference: AG-CR1-3755-M025

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Mubritinib (TAK-165) is a selective inhibitor of the human epidermal growth factor receptor 2 (EGFR2; HER2), inhibiting HER2 phosphorylation with an IC50 value of 6nM. It is 4000-fold selective over EGFR, FGFR, PDGFR,...

Mubritinib

Reference: AG-CR1-3755-M005

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Mubritinib (TAK-165) is a selective inhibitor of the human epidermal growth factor receptor 2 (EGFR2; HER2), inhibiting HER2 phosphorylation with an IC50 value of 6nM. It is 4000-fold selective over EGFR, FGFR, PDGFR,...

VX-745

Reference: AG-CR1-3754-M050

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VX-745 is a potent inhibitor of p38α MAPK (IC50=10nM) with 20-fold selectivity over p38β and 1000-fold selectivity over closely related kinases, ERK1, MK2 and JNK1-3. p38α is a member of the mitogen-activated protein...

VX-745

Reference: AG-CR1-3754-M010

€0.00 (tax incl.)

VX-745 is a potent inhibitor of p38α MAPK (IC50=10nM) with 20-fold selectivity over p38β and 1000-fold selectivity over closely related kinases, ERK1, MK2 and JNK1-3. p38α is a member of the mitogen-activated protein...

VX-745

Reference: AG-CR1-3754-M005

€0.00 (tax incl.)

VX-745 is a potent inhibitor of p38α MAPK (IC50=10nM) with 20-fold selectivity over p38β and 1000-fold selectivity over closely related kinases, ERK1, MK2 and JNK1-3. p38α is a member of the mitogen-activated protein...

VX-745

Reference: AG-CR1-3754-M001

€0.00 (tax incl.)

VX-745 is a potent inhibitor of p38α MAPK (IC50=10nM) with 20-fold selectivity over p38β and 1000-fold selectivity over closely related kinases, ERK1, MK2 and JNK1-3. p38α is a member of the mitogen-activated protein...

Budesonide

Reference: AG-CR1-3753-M250

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Budesonide is a glucocorticoid and an agonist of glucocorticoid receptors (EC50=45.7pM in a transactivation assay), selective for glucocorticoid over mineralocorticoid receptors. Budesonide is a synthetic...

Budesonide

Reference: AG-CR1-3753-M050

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Budesonide is a glucocorticoid and an agonist of glucocorticoid receptors (EC50=45.7pM in a transactivation assay), selective for glucocorticoid over mineralocorticoid receptors. Budesonide is a synthetic...

Budesonide

Reference: AG-CR1-3753-M010

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Budesonide is a glucocorticoid and an agonist of glucocorticoid receptors (EC50=45.7pM in a transactivation assay), selective for glucocorticoid over mineralocorticoid receptors. Budesonide is a synthetic...

AZ 960

Reference: AG-CR1-3752-M025

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AZ-960 is a potent, selective and ATP-competitive JAK2 inhibitor that inhibits JAK2 kinase with a Ki of 0.45nM in vitro (3-fold selective over JAK3) and induces growth arrest and apoptosis in adult T cell leukemia...

AZ 960

Reference: AG-CR1-3752-M005

€0.00 (tax incl.)

AZ-960 is a potent, selective and ATP-competitive JAK2 inhibitor that inhibits JAK2 kinase with a Ki of 0.45nM in vitro (3-fold selective over JAK3) and induces growth arrest and apoptosis in adult T cell leukemia...

AZ 960

Reference: AG-CR1-3752-M001

€0.00 (tax incl.)

AZ-960 is a potent, selective and ATP-competitive JAK2 inhibitor that inhibits JAK2 kinase with a Ki of 0.45nM in vitro (3-fold selective over JAK3) and induces growth arrest and apoptosis in adult T cell leukemia...

Efavirenz

Reference: AG-CR1-3751-M250

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Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that exhibits antiviral and anticancer activities. Efavirenz binds to wild-type and mutant HIV-1 RTs (Ki= 2.93nM and 3.85-56.5nM, respectively). It...

Efavirenz

Reference: AG-CR1-3751-M050

€0.00 (tax incl.)

Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that exhibits antiviral and anticancer activities. Efavirenz binds to wild-type and mutant HIV-1 RTs (Ki= 2.93nM and 3.85-56.5nM, respectively). It...

Efavirenz

Reference: AG-CR1-3751-M010

€0.00 (tax incl.)

Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that exhibits antiviral and anticancer activities. Efavirenz binds to wild-type and mutant HIV-1 RTs (Ki= 2.93nM and 3.85-56.5nM, respectively). It...

Rilpivirine

Reference: AG-CR1-3750-M025

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Rilpivirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that inhibits growth of wild-type HIV with an EC50 value of 0.51nM. It is active against NNRTI-resistant HIV strains with EC50 values less than...

Rilpivirine

Reference: AG-CR1-3750-M005

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Rilpivirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that inhibits growth of wild-type HIV with an EC50 value of 0.51nM. It is active against NNRTI-resistant HIV strains with EC50 values less than...

Opaganib

Reference: AG-CR1-3749-M100

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Opaganib is a selective inhibitor of sphingosine kinase 2 (SPHK2; Ki = 9.8 μM), a lipid kinase that catalyzes formation of the lipid signaling molecule sphingosine 1-phosphate (S1P). S1P promotes cancer growth, and...

Opaganib

Reference: AG-CR1-3749-M025

€0.00 (tax incl.)

Opaganib is a selective inhibitor of sphingosine kinase 2 (SPHK2; Ki = 9.8 μM), a lipid kinase that catalyzes formation of the lipid signaling molecule sphingosine 1-phosphate (S1P). S1P promotes cancer growth, and...

Opaganib

Reference: AG-CR1-3749-M005

€0.00 (tax incl.)

Opaganib is a selective inhibitor of sphingosine kinase 2 (SPHK2; Ki = 9.8 μM), a lipid kinase that catalyzes formation of the lipid signaling molecule sphingosine 1-phosphate (S1P). S1P promotes cancer growth, and...

PF-0477736

Reference: AG-CR1-3537-M050

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PF-0477736 is a potent, selective ATP-competitive inhibitor of Chk1 (Ki = 0.49nM) with 100-fold selectivity over Chk2 (Ki = 47nM). When used in combination with various chemotherapeutics (e.g. gemcitabine and...

PF-0477736

Reference: AG-CR1-3537-M010

€0.00 (tax incl.)

PF-0477736 is a potent, selective ATP-competitive inhibitor of Chk1 (Ki = 0.49nM) with 100-fold selectivity over Chk2 (Ki = 47nM). When used in combination with various chemotherapeutics (e.g. gemcitabine and...

PF-0477736

Reference: AG-CR1-3537-M005

€0.00 (tax incl.)

PF-0477736 is a potent, selective ATP-competitive inhibitor of Chk1 (Ki = 0.49nM) with 100-fold selectivity over Chk2 (Ki = 47nM). When used in combination with various chemotherapeutics (e.g. gemcitabine and...

XD14

Reference: SYN-3048-M100

€0.00 (tax incl.)

BET bromodomain inhibitor with Kd values of 160, 170, 380, 490, 830 and 850nM for BRD4(1), BRD2(1), BRD3(1), BRD3(2), BRD2(2) and BRD4(2), respectively. XD14 also inhibits BRDT(1), CBP, p300 and BRDT(2) with Kd values...

XD14

Reference: SYN-3048-M050

€0.00 (tax incl.)

BET bromodomain inhibitor with Kd values of 160, 170, 380, 490, 830 and 850nM for BRD4(1), BRD2(1), BRD3(1), BRD3(2), BRD2(2) and BRD4(2), respectively. XD14 also inhibits BRDT(1), CBP, p300 and BRDT(2) with Kd values...

XD14

Reference: SYN-3048-M010

€0.00 (tax incl.)

BET bromodomain inhibitor with Kd values of 160, 170, 380, 490, 830 and 850nM for BRD4(1), BRD2(1), BRD3(1), BRD3(2), BRD2(2) and BRD4(2), respectively. XD14 also inhibits BRDT(1), CBP, p300 and BRDT(2) with Kd values...

XD14

Reference: SYN-3048-M005

€0.00 (tax incl.)

BET bromodomain inhibitor with Kd values of 160, 170, 380, 490, 830 and 850nM for BRD4(1), BRD2(1), BRD3(1), BRD3(2), BRD2(2) and BRD4(2), respectively. XD14 also inhibits BRDT(1), CBP, p300 and BRDT(2) with Kd values...

XD14

Reference: SYN-3048-M001

€0.00 (tax incl.)

BET bromodomain inhibitor with Kd values of 160, 170, 380, 490, 830 and 850nM for BRD4(1), BRD2(1), BRD3(1), BRD3(2), BRD2(2) and BRD4(2), respectively. XD14 also inhibits BRDT(1), CBP, p300 and BRDT(2) with Kd values...

PFI-4

Reference: SYN-3047-M100

€0.00 (tax incl.)

Potent and selective BRPF1 bromodomain inhibitor, with an IC50 of 80nM. PFI-4 exhibits >100-fold selectivity for BRPF1 over a panel of other bromodomains including BRPF2 (BRD1), BRPF3 and BRD4. PFI-4 specifically...

PFI-4

Reference: SYN-3047-M050

€0.00 (tax incl.)

Potent and selective BRPF1 bromodomain inhibitor, with an IC50 of 80nM. PFI-4 exhibits >100-fold selectivity for BRPF1 over a panel of other bromodomains including BRPF2 (BRD1), BRPF3 and BRD4. PFI-4 specifically...

PFI-4

Reference: SYN-3047-M010

€0.00 (tax incl.)

Potent and selective BRPF1 bromodomain inhibitor, with an IC50 of 80nM. PFI-4 exhibits >100-fold selectivity for BRPF1 over a panel of other bromodomains including BRPF2 (BRD1), BRPF3 and BRD4. PFI-4 specifically...

PFI-4

Reference: SYN-3047-M005

€0.00 (tax incl.)

Potent and selective BRPF1 bromodomain inhibitor, with an IC50 of 80nM. PFI-4 exhibits >100-fold selectivity for BRPF1 over a panel of other bromodomains including BRPF2 (BRD1), BRPF3 and BRD4. PFI-4 specifically...

PFI-4

Reference: SYN-3047-M001

€0.00 (tax incl.)

Potent and selective BRPF1 bromodomain inhibitor, with an IC50 of 80nM. PFI-4 exhibits >100-fold selectivity for BRPF1 over a panel of other bromodomains including BRPF2 (BRD1), BRPF3 and BRD4. PFI-4 specifically...

AZ9482

Reference: SYN-3046-M100

€0.00 (tax incl.)

AZ9482 is a potent and selective PARP inhibitor featuring an amide linkage to a 2-piperazinyl-3-cyano-pyridine. AZ9482 exhibits very potent centrosome declustering activity in HeLa cells (EC50 < 18nM). AZ9482 also...

AZ9482

Reference: SYN-3046-M050

€0.00 (tax incl.)

AZ9482 is a potent and selective PARP inhibitor featuring an amide linkage to a 2-piperazinyl-3-cyano-pyridine. AZ9482 exhibits very potent centrosome declustering activity in HeLa cells (EC50 < 18nM). AZ9482 also...

AZ9482

Reference: SYN-3046-M010

€0.00 (tax incl.)

AZ9482 is a potent and selective PARP inhibitor featuring an amide linkage to a 2-piperazinyl-3-cyano-pyridine. AZ9482 exhibits very potent centrosome declustering activity in HeLa cells (EC50 < 18nM). AZ9482 also...

AZ9482

Reference: SYN-3046-M005

€0.00 (tax incl.)

AZ9482 is a potent and selective PARP inhibitor featuring an amide linkage to a 2-piperazinyl-3-cyano-pyridine. AZ9482 exhibits very potent centrosome declustering activity in HeLa cells (EC50 < 18nM). AZ9482 also...

AZ9482

Reference: SYN-3046-M001

€0.00 (tax incl.)

AZ9482 is a potent and selective PARP inhibitor featuring an amide linkage to a 2-piperazinyl-3-cyano-pyridine. AZ9482 exhibits very potent centrosome declustering activity in HeLa cells (EC50 < 18nM). AZ9482 also...

EPZ-6438

Reference: SYN-3045-M100

€0.00 (tax incl.)

EPZ6438 is a potent orally bioavailable, selective inhibitor of the lysine methyltranferase EZH2 (Ki = 2.5nM), the enzymatic subunit of polycomb repressive complex It displays a 35-fold selectivity versus EZH1 and...

EPZ-6438

Reference: SYN-3045-M050

€0.00 (tax incl.)

EPZ6438 is a potent orally bioavailable, selective inhibitor of the lysine methyltranferase EZH2 (Ki = 2.5nM), the enzymatic subunit of polycomb repressive complex It displays a 35-fold selectivity versus EZH1 and...

EPZ-6438

Reference: SYN-3045-M010

€0.00 (tax incl.)

EPZ6438 is a potent orally bioavailable, selective inhibitor of the lysine methyltranferase EZH2 (Ki = 2.5nM), the enzymatic subunit of polycomb repressive complex It displays a 35-fold selectivity versus EZH1 and...

EPZ-6438

Reference: SYN-3045-M005

€0.00 (tax incl.)

EPZ6438 is a potent orally bioavailable, selective inhibitor of the lysine methyltranferase EZH2 (Ki = 2.5nM), the enzymatic subunit of polycomb repressive complex It displays a 35-fold selectivity versus EZH1 and...

EPZ-6438

Reference: SYN-3045-M001

€0.00 (tax incl.)

EPZ6438 is a potent orally bioavailable, selective inhibitor of the lysine methyltranferase EZH2 (Ki = 2.5nM), the enzymatic subunit of polycomb repressive complex It displays a 35-fold selectivity versus EZH1 and...

EPZ015666

Reference: SYN-3044-M100

€0.00 (tax incl.)

Protein arginine methyltransferase-5 (PRMT5) is reported to have a role in diverse cellular processes, including tumorigenesis and its overexpression is observed in cell lines and primary patient samples derived from...

EPZ015666

Reference: SYN-3044-M050

€0.00 (tax incl.)

Protein arginine methyltransferase-5 (PRMT5) is reported to have a role in diverse cellular processes, including tumorigenesis and its overexpression is observed in cell lines and primary patient samples derived from...

EPZ015666

Reference: SYN-3044-M010

€0.00 (tax incl.)

Protein arginine methyltransferase-5 (PRMT5) is reported to have a role in diverse cellular processes, including tumorigenesis and its overexpression is observed in cell lines and primary patient samples derived from...

EPZ015666

Reference: SYN-3044-M005

€0.00 (tax incl.)

Protein arginine methyltransferase-5 (PRMT5) is reported to have a role in diverse cellular processes, including tumorigenesis and its overexpression is observed in cell lines and primary patient samples derived from...

EPZ015666

Reference: SYN-3044-M001

€0.00 (tax incl.)

Protein arginine methyltransferase-5 (PRMT5) is reported to have a role in diverse cellular processes, including tumorigenesis and its overexpression is observed in cell lines and primary patient samples derived from...

Oraparib

Reference: SYN-3043-M100

€0.00 (tax incl.)

The PARP inhibitor Olaparib (AZD2281) is a small molecule inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase (PARP) with potential chemosensitizing, radiosensitizing and antineoplastic activities. Olaparib...

Oraparib

Reference: SYN-3043-M050

€0.00 (tax incl.)

The PARP inhibitor Olaparib (AZD2281) is a small molecule inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase (PARP) with potential chemosensitizing, radiosensitizing and antineoplastic activities. Olaparib...

Oraparib

Reference: SYN-3043-M010

€0.00 (tax incl.)

The PARP inhibitor Olaparib (AZD2281) is a small molecule inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase (PARP) with potential chemosensitizing, radiosensitizing and antineoplastic activities. Olaparib...

Oraparib

Reference: SYN-3043-M005

€0.00 (tax incl.)

The PARP inhibitor Olaparib (AZD2281) is a small molecule inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase (PARP) with potential chemosensitizing, radiosensitizing and antineoplastic activities. Olaparib...

Oraparib

Reference: SYN-3043-M001

€0.00 (tax incl.)

The PARP inhibitor Olaparib (AZD2281) is a small molecule inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase (PARP) with potential chemosensitizing, radiosensitizing and antineoplastic activities. Olaparib...