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Reference: abx076838
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Reference: abx282560
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Reference: GRP382
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The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing...
Reference: GRP277
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ZNF300 contains C2H2 (or Kruppel)-type zinc finger motifs that tetrahedrally coordinate zinc ions and form a protein structure that can bind DNA and regulate transcription (Gou et al.,2004 [PubMed 14746915]). ZNF300...
Reference: abx076701
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Reference: abx076776
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Reference: abx076720
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Reference: abx283239
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Reference: abx282085
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Reference: abx076528
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Reference: GRP38
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ZEB1 encodes a zinc finger transcription factor that represses T-lymphocyte-specific IL2 gene (MIM 147680) expression by binding to a negative regulatory domain 100 nucleotides 5-prime of the IL2 transcription start...
Reference: abx082380
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Reference: GRP230
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Exhibits a cytosolic function in lipogenesis, adipogenic differentiation, and lipid homeostasis by increasing the activity of ACLY, possibly preventing its dephosphorylation. May act as a transcriptional repressor....
Reference: GRP596
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Exhibits a cytosolic function in lipogenesis, adipogenic differentiation, and lipid homeostasis by increasing the activity of ACLY, possibly preventing its dephosphorylation. May act as a transcriptional repressor....
Reference: abx076598
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Reference: abx282358
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Reference: abx076595
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Reference: abx076594
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Reference: abx282420
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Reference: abx076548
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Reference: abx282369
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Reference: GRP423
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Transcription factor essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response (UPR). Acts during endoplasmic reticulum stress (ER) by...
Reference: abx076690
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Reference: abx082535
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Reference: abx082320
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Reference: abx283063
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Reference: abx076749
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Reference: GRP271
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Putative oxidoreductase. Acts as a tumor suppressor and plays a role in apoptosis. Required for normal bone development (By similarity). May function synergistically with p53/TP53 to control genotoxic stress-induced...
Reference: abx283124
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Reference: abx076791
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Reference: GRP444
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Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In...
Reference: GRP426
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Ligand for members of the frizzled family of seven transmembrane receptors. Wnt-3 and Wnt-3a play distinct roles in cell-cell signaling during morphogenesis of the developing neural tube.
Reference: GRP429
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Ligand for members of the frizzled family of seven transmembrane receptors. In some developmental processes, is also a ligand for the coreceptor RYK, thus triggering Wnt signaling. Probable developmental protein. May...
Reference: abx283070
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Reference: abx076573
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Reference: abx283209
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Reference: abx282561
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Reference: abx076817
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Reference: GRP219
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This is a receptor for VIP as well as PACAP-38 and -27, the activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Can be coupled to phospholipase C.
Reference: GRP18
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Von Hippel-Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors. A germline mutation of this gene is the basis of familial inheritance of...

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