Antibodies (12)

Efineptakin alfa

Reference: HY-P99908

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Efineptakin alfa (NT-17) is a long-acting recombinant human IL-7. Efineptakin alfa supports the proliferation and survival CD4+ and CD8+ cells in both human and mice. Efineptakin alfa can be used for glioblastoma...

Demcizumab

Reference: HY-P99261

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Demcizumab (OMP 21M18) is an anti-DLL4 monoclonal antibody. Demcizumab is a potent inhibitor of the Notch pathway. Demcizumab alone or in combination with chemotherapy is effective in various cancer models.

Ponsegromab

Reference: HY-P99241

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Ponsegromab (PF 06946860) is a potent and selective humanized anti-GDF15 antibody inhibitor with anti-cachexia activity. Ponsegromab binds to GDF15 and prevents the binding of GDF15 to GFRAL, thereby blocking...

Astegolimab

Reference: HY-P99444

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Astegolimab (MSTT 1041A; RG 6149) is a human IgG2 monoclonal antibody that blocks IL-33 signaling by targeting ST2, the IL-33 receptor. Astegolimab has the potential for chronic obstructive pulmonary disease (COPD)...

Enibarcimab

Reference: HY-P99177

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Enibarcimab is a humanised murine monoclonal immunoglobulin G1 (IgG1) antibody, could be used for acute heart failure, COVID-19 infections and septic shock research.

Rafivirumab

Reference: HY-P99811

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Rafivirumab (CR57) is an anti-rabies virus monoclonal antibody for the prophylaxis of rabies. Rafivirumab has neutralizing potency against a broad spectrum of RABV variants. Rafivirumab can be used for research of...

Plonmarlimab

Reference: HY-P99779

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Plonmarlimab (TJ003234) is an anti-GM-CSF monoclonal antibody. Plonmarlimab can be used for research of rheumatoid arthritis and COVID-19.

Exidavnemab

Reference: HY-P99609

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Exidavnemab (ABBV-0805; BAN-0805) is a human IgG4 monoclonal antibody that selectively targets soluble human α-synuclein aggregates with a KD value of 18.5 pM and a KD value of 2.2 μM for α-synuclein monomers....

Atacicept

Reference: HY-P99446

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Atacicept (TACI-Ig) is a is a recombinant fusion protein containing the extracellular, ligand-binding portion of the TACI receptor and the Fc portion of human IgG. Atacicept inhibits B cell stimulation by binding to B...

Fulranumab

Reference: HY-P99200

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Fulranumab is a human IgG2 monoclonal antibody against nerve growth factor (NGF) and can be used for the research of pain.

Vixtimotamab

Reference: HY-P99958

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Vixtimotamab (AMV-564; TandAb T564) is a bispecific tetravalent tandem diabody (TandAb) that targets human CD33 and human CD3 antigens. Vixtimotamab can be used for the research of acute myeloid leukemia (AML).

Inbakicept

Reference: HY-P99661

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Inbakicept (ALT-803) is an IL-15 superagonist complex, consisting of IL-15 mutant and IL-15Rα-Fc fusion. Inbakicept magnifies anti-CD20 mAb-mediated NK-cell responses and antibody-dependent cellular cytotoxicity...

Bococizumab

Reference: HY-P99187

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Bococizumab (PF-04950615) is an anti-human PCSK9 inhibitory antibody that reduces LDL cholesterol levels. Bococizumab can be used in the research of hypercholesterolemia.

Lomtegovimab

Reference: HY-P99710

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Lomtegovimab (BI 767551) is a humanized anti-SARS-COV-2 spike glycoprotein monoclonal antibody. Lomtegovimab binds and neutralizes SARS-CoV-2. Lomtegovimab shows antiviral efficacy. Lomtegovimab has the potential for...

Toripalimab

Reference: HY-P9978

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Toripalimab is the first domestic anti-tumor PD-1 antibody in China. Toripalimab is a selective, recombinant, humanized monoclonal antibody against PD-1. Toripalimab is able to bind to PD-1 and block the interaction...

Ripafollitropin alfa (bovine)

Reference: HY-P99951

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Ripafollitropin alfa (bovine) is a recombinant follicle-stimulating hormone fusion protein with chorionic gonadotropin.

Igovomab

Reference: HY-P9943

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Igovomab is a monoclonal antibody for imaging. Igovomab can be used for ovarian cancer research.

Girentuximab

Reference: HY-P99023

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Girentuximab (G250) is a chimeric monoclonal antibody that binds carbonic anhydrase IX (CAIX), a cell surface glycoprotein ubiquitously expressed in clear cell renal cell carcinoma (ccRCC).

Bavituximab

Reference: HY-P99279

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Bavituximab (Anti-Human Phosphatidylserine Recombinant Antibody) is a phosphatidylserine (PS)-targeting monoclonal antibody, suppresses tumor growth by targeting tumor vasculature and reactivating antitumor immunity....

Raleukin

Reference: HY-108841

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Raleukin (AMG-719) is a recombinant, nonglycosylated human interleukin-1 receptor (IL-1R) antagonist. Raleukin (AMG-719) is the first biological agent to block the pro-inflammatory effects.

Anti-Mouse IL-1b Antibody

Reference: HY-P99139

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Anti-Mouse IL-1b Antibody is an anti-mouse IL-1b IgG antibody inhibitor derived from host Armenian Hamster.

Teneliximab

Reference: HY-P99321

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Teneliximab (BMS-224819) is a chimeric monoclonal antibody, blocks the CD40-CD40L interaction. Teneliximab (BMS-224819) has partial agonist activity resulting in some signaling through CD40 and peripheral B cell...

Anti-Mouse CD90.2 Antibody

Reference: HY-P99131

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Anti-Mouse CD90.2 Antibody is an anti-mouse CD90.2 IgG2b antibody inhibitor derived from host Rat.

Livmoniplimab

Reference: HY-P99708

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Livmoniplimab (ABBV-151; ARGX-115) is a potent humanized anti-LRRC32 (GARP)/TGFβ1 monoclonal antibody. Livmoniplimab blocks LRRC32-mediated activation of latent TGFβ1. Livmoniplimab has the potential for the research...

Tixagevimab

Reference: HY-P99556

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Tixagevimab (AZD8895) is a human monoclonal antibody that targets the SARS-CoV-2 receptor binding domain (RBD). It exhibits neutralizing activity against SARS-CoV-2 by binding to the RBD and the S-glycoprotein...

Inezetamab

Reference: HY-P99663

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Inezetamab is a bispecific anti-CD40 and anti-MSLN IgG1 monoclonal antibody.

Tamtuvetmab

Reference: HY-P99579

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Tamtuvetmab (AT-005) is a caninised blontuvetmab against CD52. Tamtuvetmab increases progression-free survival (PFS), exhibits in vivo efficacy in dogs with naïve T-cell lymphoma (LSA). Tamtuvetmab has been approved...

Veltuzumab

Reference: HY-P99224

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Veltuzumab (IMMU-106) is a humanized anti-CD20 monoclonal antibody. Veltuzumab has low EC50 value of 0.08-0.09 μg/mL in the Daudi cell line. Veltuzumab can be used for the research of cancer including non-Hodgkin...

Lanadelumab

Reference: HY-P99110

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Lanadelumab (SHP643) is a humanized IgG1 monoclonal antibody against plasma kallikrein (pKal) with an Ki value of 0.12 nM. Lanadelumab inhibits both free and HMWK (high molecular weight kininogen)-bound pKal....

Enoblituzumab

Reference: HY-P9966

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Enoblituzumab (MGA271) is a humanized IgG1κ monoclonal antibody recognizing human B7-H3 protein, a member of the B7 family of immune regulators.

Clervonafusp alfa

Reference: HY-P99803

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Clervonafusp alfa (VAL-1221) is a fusion protein targeting both cytosolic and lysosomal glycogen. Clervonafusp alfa is comprised of the Fab portion of a cell-penetrating antibody and recombinant human acid alpha...

Magrolimab

Reference: HY-P99029

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Magrolimab (Hu5F9-G4) is a first-in-class humanized anti-CD47 IgG4 antibody with an anti-tumor activity.

Trinbelimab

Reference: HY-P99545

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Trinbelimab (r-anti-D) is an antibody. Trinbelimab can be used for various biochemical studies.

Cirevetmab

Reference: HY-P99606

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Cirevetmab (ZTS-00521426) is an immunoglobulin G2-kappa, Canis lupus familiaris TGFB1 caninized monoclonal antibody. Cirevetmab is an immunomodulator.

Pavurutamab

Reference: HY-P99814

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Pavurutamab (AMG-701) is a bispecific T cell engager molecule that anti-CD3 and anti-B cell maturation antigens (BCMA). Pavurutamab has an extended half-life based on Pacanalotamab (HY-P99798). The Fc of Pavurutamab...

Firivumab

Reference: HY-P99620

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Firivumab (CT-P22; CT120) is a human IgG1 monoclonal influenza A virus hemagglutinin (Anti-IAV HA) antibody. Firivumab is capable of neutralizing H1N1, H5N1, H6N1, H6N2, H8N4, H8N8, H9N2 and H12N7. Firivumab shows...

Anti-SARS-CoV-2 Spike mAb (CR3022)

Reference: HY-P9807

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Anti-SARS-CoV-2 Spike mAb (CR3022) is a a CHO cell derived human monoclonal IgG1 antibody. It binds to both S1 domain of SARS-CoV/SARS-CoV-2 Spike protein.

Idactamab

Reference: HY-P99654

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Idactamab (INT-001) is an IgG1-κ antibody with in vivo activity across a spectrum of hematological malignancies. Idactamab can be used for prepare MEDI7247, a potent and specific ADC, targeting ASCT2 (SLC1A5).

Vepsitamab

Reference: HY-P99523

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Vepsitamab (AMG 199) is an anti-MUC17/CD3 BiTE antibody that binds to CD3 on T cells and MUC17 expressed on tumor cells, mediates redirected tumor cell lysis, and induces T cell activation and proliferation.

Tidutamab

Reference: HY-P99562

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Tidutamab (XmAb-18087) is a humanized and affinity-optimized bispecific antibody (bsAb) targeting SSTR2 binding domain and T-cell binding domain (CD3). Tidutamab possesses a full Fc domain to maintain long serum...

Mitazalimab

Reference: HY-P99742

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Mitazalimab (ADC-1013; JNJ-64457107) is FcγR-dependent CD40 agonist with tumor-directed activity. Mitazalimab activates antigen-presenting cells, e.g. dendritic cells (DC), to initiate tumor-reactive T cells....

Teropavimab

Reference: HY-P99564

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Teropavimab (3BNC117-LS) is an antibody. Teropavimab can be used for the research of HIV infection.

Bertilimumab

Reference: HY-P99474

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Bertilimumab (CAT 213; iCo-008) is a human monoclonal antibody targeting eotaxin-1 (CCL11). Bertilimumab has the potential for allergic disorders research.

Izokibep

Reference: HY-P99678

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Izokibep (ABY-035) is a selective and antibody mimetic interleukin 17A (IL-17A) inhibitor with high potency and long half-life. Izokibep can be used for the research of ankylosing spondylitis, atherosclerosis and skin...

Blontuvetmab

Reference: HY-P99483

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Blontuvetmab (AT 004)is a caninized CD20 monoclonal antibody. Blontuvetmab can be used for the research of Canine B-cell lymphoma.

Tucotuzumab

Reference: HY-P99328

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Tucotuzumab (Anti-EPCAM Recombinant Antibody) is a protein composed of an IgG1 monoclonal antibody specific for the human Epithelial Cell Adhesion Molecule (EpCAM) antigen, linked to two molecules of IL-2. Tucotuzumab...

Imdevimab

Reference: HY-P99342

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Imdevimab (REGN10987) is a human monoclonal antibody to target SARS-CoV-2 virus, which causes COVID-19. Imdevimab lacks efficacy against COVID-19 variants. Imdevimab can be used in combination with Casirivimab...

Befovacimab

Reference: HY-P99465

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Befovacimab (BAY 1093884) is a fully human monoclonal IgG2 antibody able to bind to tissue factor pathway inhibitor (TFPI). Befovacimab can be used for haemophilia A/B research.

Prasinezumab

Reference: HY-P99405

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Prasinezumab (PRX 002) is a humanized IgG1 monoclonal antibody directed against aggregated α-synuclein. Prasinezumab has the potential for Parkinson's disease research.

Vopratelimab

Reference: HY-P99382

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Vopratelimab (JTX-2011) is a humanized immunoglobulin G1-kappa agonist monoclonal antibody that pecifically binds to the Inducible CO-Stimulator of T cells (ICOS). Vopratelimab retains species cross-reactivity with...

Icrucumab

Reference: HY-P99364

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Icrucumab (Anti-VEGFR1/FLT1 Reference Antibody; IMC-18F1) is a humanized Anti-VEGFR-1 IgG1 monoclonal antibody. Icrucumab has the potential for the research of advanced solid tumors.

Ieramilimab

Reference: HY-P99027

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Ieramilimab (LAG525; IMP701) is a humanized IgG4 monoclonal antibody that binds to LAG-3, resulting in inhibition of LAG-3 interaction with MHC-II molecules.

Sudubrilimab

Reference: HY-P99963

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Sudubrilimab (HS636) is an Ig G1-kappa monoclonal antibody against PDL1. Sudubrilimab is fused at the C terminus of the heavy chain to a TGF-β1 receptor Ⅱ ectodomain (TGFBR2-ECD), and which can sequester the...

Batiraxcept

Reference: HY-P99463

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Batiraxcept (AVB-S6-500) is a highly potent and specific AXL inhibitor, a recombinant fusion protein dimer containing the extracellular domain of human AXLM and human immunoglobulin G1 heavy chain (Fc). Batiraxcept...

Disitamab

Reference: HY-P99854

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Disitamab (RC48-0) is a humanized monoclonal antibody targeting HER2. Disitamab can be used in the synthesis of antibody-drug conjugates (ADCs), Disitamab vedotin (Disitamab vedotin (HY-P9985)).

Zampilimab

Reference: HY-P99512

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Zampilimab (UCB-7858) is a monoclonal antibody against transglutaminase 2 (TG2). Zampilimab has potential application in renal transplant.

CTX-471

Reference: HY-P99178

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CTX-471 is a fully human monoclonal antibody of CD137. CTX-471 has bind affinity for recombinant human, cynomolgus macaque CD137 and mouse CD137 with Kd values of 50 nM, 61 nM and 748 nM, respectively. CTX-471 can be...

Latikafusp

Reference: HY-P99687

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Latikafusp (AMG 256) is a bifunctional fusion protein comprising a PD-1-targeting antibody and IL-21 mutein designed to deliver IL-21 pathway stimulation to PD-1+ cells. Latikafusp is designed to prime and extend the...

Simtuzumab

Reference: HY-P99047

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Simtuzumab (AB 0024; GS 6624) is a monoclonal antibody directed against Lysyl oxidase like-2 (LOXL2). Simtuzumab can be used for the research of primary sclerosing cholangitis (PSC).

Orticumab

Reference: HY-P99793

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Orticumab (MLDL1278A) is an antibody targeting to oxidized or malondialdehyde-modified lipoprotein (LDL). Orticumab specifically inhibits oxidized low-density lipoproteins (oxLDL). Orticumab involves in modulation of...

Geptanolimab

Reference: HY-P99639

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Geptanolimab (CBT-501) is a humanized IgG4k monoclonal antibody against programmed death-1 (PD-1). Siplizumab inhibits the binding of PD-L1/L2 to PD-1 through a competitive action. Siplizumab can be used in research...

Naptumomab

Reference: HY-P99035

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Naptumomab, a tumor targeting superantigen (TTS), is a fusion protein containing. Naptumomab stimulates the immune system to identify and kill tumour cells. Naptumomab can be used for the research of refractory solid...

Teclistamab

Reference: HY-P99392

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Teclistamab is a human bispecific antibody to BCMA and CD3 that recognizes BCMA on target cells and CD3 on T cells and induces T cell-mediated cytotoxicity leading to T cell activation and subsequent target cell...

Crovalimab

Reference: HY-P99965

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Crovalimab (SKY59; RO7112689) is a novel humanized antibody against C5 in a pH-dependent manner with KDs of 15.2 nM and 16.8 μM at pH 7.4 and 5.8, respectively. Crovalimab binds human FcRn with great affinity (KD: 17...

Trastuzumab beta

Reference: HY-P99548

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Trastuzumab beta (ABP 980) is a biosimilar to Trastuzumab (HY-P9907). Trastuzumab beta is a monoclonal antibody (McAb) targeting human epidermal growth factor receptor 2 (HER2). Trastuzumab beta can be used for the...

Gatipotuzumab

Reference: HY-P99634

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Gatipotuzumab (PankoMab) is a humanized monoclonal antibody which recognizes the tumor-specific epitope of mucin-1 (TA-MUC1). Gatipotuzumab reveals a potent tumor-specific antibody-dependent cell cytotoxicity (ADCC).

Flanvotumab

Reference: HY-P99622

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Flanvotumab (IMC-20D7S) is a human monoclonal antibody targeting to tyrosinase-related protein (TYRP1), specifically expressed in melanocytes and melanoma cells. Flanvotumab acts function via natural killing-mediated...

Inotuzumab

Reference: HY-P99264

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Inotuzumab (Humanized Anti-CD22 Recombinant Antibody) is a humanized IgG4, κ antibody that targets human CD22. Inotuzumab can be linked to a toxic agent ozogamicin as an antibody-drug conjugate (ADC). Inotuzumab can...

Temelimab

Reference: HY-P99567

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Temelimab (GNbAC-1) is an IgG4 monoclonal antibody that targets the human endogenous retroviral envelope protein HERV-W-Env.

Quisovalimab

Reference: HY-P99810

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Quisovalimab (AVTX-002; AEVI 002; SAR 252067) is a human monoclonal antibody against LIGHT, a tumor necrosis factor (TNF)-related cytokine (TNFSF14) that plays an important role in acute respiratory distress syndrome...

Adecatumumab

Reference: HY-P99278

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Adecatumumab (Anti-Human EPCAM Recombinant Antibody; MT201) is a full human monoclonal antibody of the IgG1 isotype, targeting human EpCAM. Adecatumumab is expressed in almost all adenocarcinomas, and its activity is...

Perakizumab

Reference: HY-P99310

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Perakizumab (RG4934) is a humanized IgG1κ monoclonal antibody against IL-17A (Interleukin Related). Perakizumab can be uesd for the research of autoimmune diseases, such as psoriatic arthritis.

Romosozumab

Reference: HY-P9982

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Romosozumab is a humanized monoclonal anti-sclerostin antibody, it promotes bone formation and inhibits bone resorption by inhibiting sclerostin. Romosozumab can be used for the research of osteoporosis.

Anti-Mouse CD11b Antibody

Reference: HY-P99121

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Anti-Mouse CD11b Antibody is an anti-mouse CD11b IgG2b antibody inhibitor derived from the host Rat.

Tilavonemab

Reference: HY-P99163

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Tilavonemab (ABBV-8E12) is a humanised anti-tau antibody that binds amino acids 25-30 near the N-terminal end of the tau protein. Tilavonemab blocks the ability of human and mouse neurons to take up tau aggregates and...

Cosfroviximab

Reference: HY-P99832

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Cosfroviximab (c13C6-FR1) is a mouse/human chimeric monoclonal antibody against Ebola virus glycoprotein (EBOV-GP).

Human IgG2 kappa, Isotype Control

Reference: HY-P99002

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Human IgG2 kappa, Isotype Control, a human monoclonal antibody, is an isotype control for human IgG2κ antibody.

Seletracetam lithium

Reference: HY-119810A

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Seletracetam (Ucb 44212) lithium, as an analog of the antiepileptic agent Levetiracetam, is a SV2A modulator for the research of epilepsy.

Ledelabricin alfa

Reference: HY-P99690

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Ledelabricin alfa is a human proteoglycan 4 (PRG4) isoform A variant. PRG4 is a joint/boundary lubricant. Ledelabricin Alfa can be used for the research arthropathy.

Nerelimomab

Reference: HY-P99753

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Nerelimomab (BAYX1351) is an anti-TNF-α antibody. Nerelimomab can be used for research of sepsis.

Obiltoxaximab

Reference: HY-P9932

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Obiltoxaximab is a potent anti-protective antigen (PA) monoclonal antibody. Obiltoxaximab plays a central role in anthrax toxin assembly and target cell intoxication. Obiltoxaximab can be used in animal‐to‐human dose...

Category: Antibodies

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