Category: Genetics

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Reference: HY-132579
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Tominersen (RG6042) is a second-generation 2′-O-(2-methoxyethyl) antisense oligonucleotide that targets huntingtin protein (HTT) mRNA and potently suppresses HTT production. Tominersen improves survival and reduces...
Reference: HY-147406
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Tonlamarsen is a angiotensinogen synthesis reducer, with antihypertensive activity.
Reference: HY-121513
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Torcitabine (2'-Deoxy-L-cytidine) is an antiviral agent. Torcitabine has the potential for chronic hepatitis B virus infection treatment.
Reference: HY-142118
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Trabedersen (AP 12009) is an antisense oligodeoxynucleotide that specifically inhibits TGF-β2 (TGF-beta/Smad). Trabedersen can be used for the study of malignant brain tumors and other solid tumors overexpressing...
Reference: HY-149906
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Trecovirsen (GEM91) is a 25-mer antisense phosphorothioate oligonucleotide targeted at the gag site of the HIV gene.
Reference: HY-13770
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Troxacitabine is nucleoside analog with potent anticancer activity.
Reference: HY-148695A
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Truncated ADR58 is obtained by truncating full-length ADR58 from 71 bases to 31 bases. Truncated ADR58 retains similar functional activity to full-length ADR58, and can be used as a highly potent and selective human...
Reference: HY-138885
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Tryptamine guanosine carbamate (TpGc) is a selective HINT1 (histidine triad nucleotide-binding protein 1) inhibitor (Ki=34 μM, Kd=3.65 μM). Tryptamine guanosine carbamate significantly enhances morphine...
Reference: HY-N8395
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Tunicamycin V (Tunicamycin A) is a nucleoside natural product that inhibits bacterial phospho-N-acetylmuramyl-pentapeptide transferase (MraY) with an IC50 of 0.35 μM. Tunicamycin V has antibacterial activties.
Reference: HY-145934
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UDP-GalNAz disodium (UDP-N-azidoacetylgalactosamine disodium) is the analogue of UDP-GalNAc. UDP-GalNAc is the donor substrate of many N-acetylgalactosaminyltransferases, enzymes which transfer GalNAc from the...
Reference: HY-147410
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Ulefnersen is a RNA-binding protein fused-in sarcoma (FUS) synthesis reducer. Ulefnersen can be used in Amyotrophic Lateral Sclerosis (ALS) research.
Reference: HY-147412
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Ultevursen (QR-421a) is a single-stranded RNA based oligonucleotide that is designed to skip exon 13 in the RNA with the aim to stop vision loss in people that have retinitis pigmentosa due to a mutation in exon 13 of...
Reference: HY-W440810
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Undecyl 6-bromohexanoate can be useful for the preparation of lipid nanoparticles.
Reference: HY-152872
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Uridine-5-oxo-acetyl-(9-fluorenylmethyl) ester is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process...
Reference: HY-152594
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Uridine-5-oxyacetic acid is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of...
Reference: HY-148511
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Vidutolimod (CMP-001) is a CpG-A oligodeoxynucleotide. Vidutolimod is a Toll-like receptor 9 (TLR9) agonist, which activates plasmacytoid dendritic cells (pDCs) and triggers interferon alpha (IFNα) release, leading...
Reference: HY-132586
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Viltolarsen (NS-065/NCNP-01), a phosphorodiamidate morpholino antisense oligonucleotide, targets the splicing of exon 53 in the dystrophin gene. Viltolarsen can be used for the research of the Duchenne muscular...
Reference: HY-145727
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Volanesorsen is an antisense oligonucleotide thay targes Apolipoprotein C-III (APOC3) mRNA. Volanesorsen is used for the study of familial chylomicronemia syndrome.
Reference: HY-153497
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Vupanorsen is an N-acetyl galactosamine-conjugated antisense oligonucleotide that inhibits Angiopoietin-like 3 (ANGPTL3) protein synthesis. Vupanorsen lowers triglycerides and atherogenic lipoproteins.
Reference: HY-153497A
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Vupanorsen (sodium) is an N-acetyl galactosamine-conjugated antisense oligonucleotide that inhibits Angiopoietin-like 3 (ANGPTL3) protein synthesis. Vupanorsen (sodium) lowers triglycerides and atherogenic lipoproteins.
Reference: HY-132589
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Vutrisiran (ALN-TTRsc02) is a liver-directed, investigational, small interfering ribonucleic acid (siRNA) agent. Vutrisiran can be used for transthyretin (TTR)-mediated amyloidosis research.
Reference: HY-145638A
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Xalnesiran (sodium) is siRNA for the treatment of chronic hepatitis B (HBV)..
Reference: HY-W013803
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Xanthosine dihydrate is a nucleoside derived from xanthine and ribose. Xanthosine dihydrate can increase mammary stem cell population and milk production in cattle and goats.
Reference: HY-145794
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ZA3-Ep10 is a zwitterionic lipid used in lipid nanoparticles formulation for in vivo RNA delivery and non-viral CRISPR/Cas gene editing.
Reference: HY-147425
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Zerlasiran is an apolipoprotein A (ApoA) synthesis reducer.
Reference: HY-147426
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Zifcasiran is a hypoxia-inducible factor (HIF) synthesis reducer. Zifcasiran shows antitumor activities and can be used in advanced renal cell carcinoma research.
Reference: HY-145969
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β-S-ARCA is a mRNA 7-methylguanosine (m7G) cap analog carrying a phosphorothioate (PS) moiety. mRNAs incorporating β-S-ARCA have elongated cellular half-lives and showed augmented protein expression. β-S-ARCA D1 has...

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