Peptides (3)

HIV gag peptide (197-205)

Reference: HY-P1885

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HIV gag peptide (197-205) is a H-2Kd-restricted epitope derived from the p24 portion of the HIV-1 gag protein, consists of amino acids 197-205 (AMQMLKETI).

BigLEN(mouse) is a potent and selective agonist of orphan G protein-coupled receptor 171 (GPR171), with a Kd of ∼0.5 nM. BigLEN(mouse) can be used to regulate responses associated with food intake and metabolism.

Z-Tyr-OtBu

Reference: HY-W022250

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Z-Tyr-OtBu is a tyrosine derivative.

Adrenomedullin (16-31), human

Reference: HY-P1770

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Adrenomedullin (16-31), human is amino acid residues 16-31 fragment of human adrenomedullin (hADM). Adrenomedullin has appreciable affinity for the CGRP1 receptor. Adrenomedullin (16-31), human possesses pressor...

(3S,4R,5S)-rel-3-(3-Chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-neopentylpyrrolidine-2-carboxylic acid

Reference: HY-78746A

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D-Proline, 3-(3-chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)-, (3S,4R,5S)-rel- is a proline derivative.

Efrilacedase alfa

Reference: HY-P3393

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Efrilacedase alfa is an active compound. Efrilacedase alfa can be used for various biochemical studies.

(S)-2-Amino-3-(pyridin-4-yl)propanoic acid dihydrochloride

Reference: HY-W022405

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(S)-2-Amino-3-(pyridin-4-yl)propanoic acid dihydrochloride is an alanine derivative.

Protein E7(43-62) TFA

Reference: HY-P2299A

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Protein E7(43-62) TFA is an E7-derived peptide with anti-tumor effects (short peptide spanning the 43th to 62th amino acid residues in the E7 protein).

Dynorphin B (1-13) (TFA)

Reference: HY-P1337A

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Dynorphin B (1-13) TFA acts as an agonist on opioid κ-receptor.

Boc-L-Valine

Reference: HY-W002300

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Boc-L-Valine is a valine derivative.

Peptide 78

Reference: HY-P2642

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Peptide 78, a chemotactic cytokine, a 78 amino acid protein member of the IL-8 or C-X-C chemokine supergene family. ENA-78 plays an important role in the elicitation of predominantly neutrophils (PMNs) into the joints...

Melittin

Reference: HY-P0233

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Melittin is a PLA2 activator, stimulates the activity of the low molecular weight PLA2, while it does not the increase activity of the high molecular weight PLA2.

Orphan GPCR SP9155 agonist P550 (mouse, rat)

Reference: HY-P2472

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Orphan GPCR SP9155 agonist P550 (mouse, rat) (26RFa (mouse, rat)), a member of the RFamide peptide family with orexigenic effect, is the cognate ligand of the mouse orphan receptor GPR103, also designated SP9155 or AQ27.

[Leu31,Pro34]-Neuropeptide Y(human,rat) TFA

Reference: HY-P1323A

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[Leu31,Pro34]-Neuropeptide Y(human,rat) TFA is a specific neuropeptide Y Y1 receptor agonist. [Leu31,Pro34]-Neuropeptide Y(human,rat) TFA slao activates Y4, Y5. [Leu31,Pro34]-Neuropeptide Y(human,rat) TFA can...

Agalactoglyco peptide

Reference: HY-P3796

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Agalactoglyco peptide is an peptide. Agalactoglyco peptide can be used for the research of various biochemical.

IGF-I (30-41)

Reference: HY-P1773

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IGF-I (30-41) is amino acids 30 to 41 fragment of Insulin-like Growth Factor I (IGF-I). IGF-I is partly responsible for systemic GH activities although it possesses a wide number of own properties (anabolic,...

Suc-Ile-Glu(γ-pip)-Gly-Arg-pNA hydrochloride

Reference: HY-P3126

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Suc-Ile-Glu(γ-pip)-Gly-Arg-pNA hydrochloride is a factor Xa specific chromogenic substrate.

(D-Lys16)-ACTH (1-24) (human, bovine, mouse, ovine, porcine, rabbit, rat)

Reference: HY-P3566

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(D-Lys16)-ACTH (1-24) (human, bovine, mouse, ovine, porcine, rabbit, rat) is the reaction product with gadolinium tetraazacyclododecanetriacetate derivative. (D-Lys16)-ACTH (1-24) (human, bovine, mouse, ovine,...

Dermorphin Analog

Reference: HY-P1577

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Dermorphin Analog is an analog of Dermorphin. Dermorphin is a natural heptapeptide μ-opioid receptor agonist found in amphibian skin.

Oxytocin parallel dimer

Reference: HY-P3215

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Oxytocin parallel dimer is the disulfide-bridged homo peptide dimer. Oxytocin dimer has oxytocin and vasopressin-like activity with less toxic than oxytocin.

N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-((4-methoxyphenyl)diphenylmethyl)-D-cysteine

Reference: HY-W037120

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N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-((4-methoxyphenyl)diphenylmethyl)-D-cysteine is a cysteine derivative.

5-Tamra-DRVYIHP

Reference: HY-P0030

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5-Tamra-DRVYIHP i a Peptide with TAMRA labeling oligonucleotide.

IRBP (1-20), human

Reference: HY-P1587

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IRBP (1-20), human contains a major epitope for the H-2b haplotype. IRBP (1-20), human induces experimental autoimmune uveoretinitis (EAU) in H-2b mice.

methyl D-cysteinate

Reference: HY-33319

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methyl D-cysteinate is a cysteine derivative.

Handle region peptide, rat

Reference: HY-P1572

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Handle region peptide, rat is a prorenin receptor antagonist, suppresses the progression of diabetic nephropathy and has anti-inflammatory in the eye.

(Glu20)-Amyloid β-Protein (1-42)

Reference: HY-P3846

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(Glu20)-Amyloid β-Protein (1-42) is a slower fibrillizing variant of amyloid β-protein (Aβ). The Glu20 mutation reduces the aggregation propensity of Aβ42 and prevents accumulation of the slowly fibrillizing peptide....

Catestatin

Reference: HY-P1271

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Catestatin is a 21-amino acid residue, cationic and hydrophobic peptide. Catestatin is an endogenous peptide that regulates cardiac function and blood pressure. Catestatin is a non-competitive nicotinic antagonist...

Pasireotide

Reference: HY-16381

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Pasireotide (SOM230), a long-acting cyclohexapeptide somatostatin analogue, can improve agonist activity at somatostatin receptors (subtypes sst1/2/3/4/5, pKi=8.2/9.0/9.1/

[D-p-Cl-Phe6,Leu17]-VIP TFA

Reference: HY-P1159A

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[D-p-Cl-Phe6,Leu17]-VIP TFA is a competitive and selective antagonist of vasoactive intestinal peptide (VIP) receptor, with the IC50 of 125.8 nM. [D-p-Cl-Phe6,Leu17]-VIP TFA has no activity on glucagon, secretin or...

Peceleganan acetate

Reference: HY-P3383A

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Peceleganan (PL-5) acetate is an artificial antimicrobial cecropin A (1-10) × melittin B (3-18) hybrid (10+16)-peptide analogue. Peceleganan acetate inhibits wound infection.

Ac-FEID-CMK TFA

Reference: HY-P3434A

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Ac-FEID-CMK TFA is a potent zebrafish-specific GSDMEb-derived peptide inhibitor. Ac-FEID-CMK TFA can attenuate the mortality and kidney injury during septic shock. Ac-FEID-CMK TFA inhibits pyroptosis and attenuates...

FNLPLGNYKKP

Reference: HY-P3587

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FNLPLGNYKKP is a peptide fragment of brain-derived acidic fibroblast growth factor.

L-Glutamate-γ-benzyl ester

Reference: HY-30232

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L-Glutamate-γ-benzyl ester is a glutamic acid derivative.

Pepinh-TRIF TFA

Reference: HY-P2565

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Pepinh-TRIF (TFA) is a 30 aa peptide that blocks TIR-domain-containing adapter-inducing interferon-β (TRIF) signaling by interfering with TLR-TRIF interaction.

Ro 106-9920

Reference: HY-107665

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Ro 106-9920 is a potent inhibitor of NF-kappaB. Ro 106-9920 has the potential for the research of tumor and cancer diseases.

Utreglutide

Reference: HY-P3388

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Utreglutide is a potent glucagon-like peptide 1 (GLP-1) receptor agonit.

Presenilin 1 (349-361)

Reference: HY-P3713

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Presenilin 1 (349-361) is an active petide, and synthetic peptides representing amino acids 349–361 can be phosphorylated by glycogen synthase kinase-3β(GSK3β) in vitro. Presenilin 1 (349-361) can be used for the...

[D-Pro2,D-Trp7,9] Substance P

Reference: HY-P3808

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[D-Pro2,D-Trp7,9] Substance P, a Substance P (HY-P0201) analogue, is a weak agonist and a potent, specific, competitive Substance P antagonist.

Phytochelatin 4

Reference: HY-P3321

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Phytochelatin 4 (PC 4) is a short Cys-rich peptide with repeating γ-Glu-Cys motifs found in plants.

HAP-1

Reference: HY-P4096

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HAP-1 is a synovial-targeted transduction peptide. HAP-1 facilitates specific internalization of protein complexes into human and rabbit synovial cells. HAP-1 fused to an antimicrobial peptide, (KLAK)2, to generate a...

LL-37, human TFA

Reference: HY-P1222A

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LL-37, human TFA is a 37-residue, amphipathic, cathelicidin-derived antimicrobial peptide, which exhibits a broad spectrum of antimicrobial activity. LL-37, human TFA could help protect the cornea from infection and...

(S)-Methyl 2-amino-2-cyclopentylacetate hydrochloride

Reference: HY-33466

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(S)-Methyl 2-amino-2-cyclopentylacetate hydrochloride is a Glycine (HY-Y0966) derivative.

Fmoc-Cys-Asp10

Reference: HY-P3497

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Fmoc-Cys-Asp10 is a non-releasable oligopeptide linker, involves in the synthesis of releasable oligopeptide linker. Releasable oligopeptide linker can be used to deliver agent to a bone fracture-homing oligopeptide...

β-Endorphin (6-31), human

Reference: HY-P3517

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β-Endorphin, an endogenous opioid neuropeptide, is an opioid receptor agonist. β-Endorphin binds preferentially to μ-opioid receptors and is produced in certain neurons of the central and peripheral nervous system and...

Ac-VDID TFA

Reference: HY-P1967

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Ac-VDID TFA is a short peptide sequence with Ac at the end.

GE 2270A

Reference: HY-106882

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GE 2270A (MDL 62879) is an antibiotic. GE 2270A inhibits gram-positive bacteria and anaerobes by inhibiting protein synthesis. GE 2270A can be used for the research of infection.

Mca-VDQVDGW-Lys(Dnp)-NH2

Reference: HY-P3476

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Mca-VDQVDGW-Lys(Dnp)-NH2 is a fluorogenic substrate of caspase-7. Mca-VDQVDGW-K(Dnp)-NH2 can be used to quantify caspase-7 activity.

ω-Agatoxin IVA

Reference: HY-P1080

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ω-Agatoxin IVA is a potent, selective P/Q type Ca2+ (Cav2.1) channel blocker with IC50s of 2 nM and 90 nM for P-type and Q-type Ca2+ channels, respectively. ω-Agatoxin IVA (IC50, 30-225 nM) inhibits glutamate...

Sinapultide

Reference: HY-P2207

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Sinapultide is a 21-amino-acid peptide that mimics the action of human surfactant protein-B (SP-B). Sinapultide can be used for synthetic phospholipids surfactants improvement.

MUC5AC motif peptide

Reference: HY-P0280

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MUC5AC motif peptide is a 16-amino acid fragment of mucin 5.

RAD16-I

Reference: HY-P2632

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RAD16-I, a soft nanofibrous self-assembling peptide, is a suitable microenvironment for human mesenchymal stem cells’ (hMSC) proliferation and differentiation into chondrocytes. RAD16-I is a well-studied ionic...

Foxy-5 TFA

Reference: HY-P1416A

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Foxy-5 TFA, a WNT5A agonist, is a mimicking peptide of WNT5A which is a non-canonical member of the Wnt family. Foxy-5 TFA triggers cytosolic free calcium signaling without affecting β-catenin activation and it...

H-Phe-Arg-OH

Reference: HY-P4554

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H-Phe-Arg-OH is a dipeptide containing phenylalanine and arginine. H-Phe-Arg-OH can be separated from Bradykinin (HY-P0206) through Angiotensin-converting enzyme (ACE, HY-P2983). H-Phe-Arg-OH can be used for metabolic...

(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P

Reference: HY-P3880

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(D-Arg1,D-Pro2,D-Trp7,9,L-Leu11)-Substance P is a neuropeptide Substance P (HY-P0201) antagonist.

Tifuvirtide

Reference: HY-P35433

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Tifuvirtide (T-1249) is a peptide human immunodeficiency virus type-1 (HIV-1) fusion inhibitor. Tifuvirtide is a synthetically designed hybrid retroviral envelope polypeptide. Tifuvirtide has antiretroviral activity....

Z-Phe-OH

Reference: HY-W011423

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Z-Phe-OH is a phenylalanine derivative.

Abz-FR-K(Dnp)-P-OH

Reference: HY-P1853

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Abz-FR-K(Dnp)-P-OH is an angiotensin I-converting enzyme (ACE) substrate and an internally quenched fluorogenic substrate for real time fluorescent assay.

Fmoc-N-Me-Asp(OtBu)-OH

Reference: HY-W013740

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Fmoc-N-Me-Asp(OtBu)-OH is an aspartic acid derivative.

TNF-α (10-36), human TFA

Reference: HY-P1825A

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TNF-α (10-36), human (TFA) is a peptide of human TNF-α.

Ac-MBP (1-11)

Reference: HY-P1734

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Ac-MBP 1-11, a short peptide sequence, is the major encephalitogenic epitope in myelin basic protein (MBP).

[Ala127] Hepatitis B Virus Pre-S Region (120-131)

Reference: HY-P4041

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[Ala127] Hepatitis B Virus Pre-S Region (120-131) is a peptide with the sequence of MQWNSTAFHQT. [Ala127] Hepatitis B Virus Pre-S Region (120-131) can be used in the activity enhancement study.

Insulin glulisine

Reference: HY-109555

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Insulin glulisine (HMR 1964) is a rapid-acting insulin analogue, it mimics the pharmacokinetic and pharmacodynamic profiles of physiological human insulin. Insulin glulisine can be used for the research of diabetes.

Fmoc-Hyp(tBu)-OH

Reference: HY-W010964

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Fmoc-Hyp(tBu)-OH is a proline derivative.

Sarafotoxin S6a

Reference: HY-P1112

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Sarafotoxin S6a, a sarafotoxin analogue, is a endothelin receptor agonist and has an ETA/ETB selectivity profile similar to that of Endothelin-3 (HY-P0204). Sarafotoxin S6a elicits the pig coronary artery with an EC50...

Protein Kinase C Peptide Substrate

Reference: HY-P1803

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Protein Kinase C Peptide Substrate is targeted to a specific cellular compartment in a manner dependent on second messengers and on specific adapter proteins in response to extracellular signals that activate...

β-Pompilidotoxin

Reference: HY-P1084

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β-Pompilidotoxin (β-PMTX), a wasp venom, can slow sodium channel inactivation and increases steady-state sodium current in cells.

(S)-2-Amino-2-methyl-3-phenylpropanoic acid

Reference: HY-W016552

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(S)-2-Amino-2-methyl-3-phenylpropanoic acid is a phenylalanine derivative.

Friulimicin D

Reference: HY-P3511

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Friulimicin D, a lipopeptide antibiotic, like Friulimicin B, is isolated from the actinomycete Actinoplanes friuliensis.

Z-Val-Osu

Reference: HY-W013774

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Z-Val-Osu is a valine derivative.

SLLK, Control Peptide for TSP1 Inhibitor

Reference: HY-P0301

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SLLK, Control Peptide for TSP1 Inhibitor is a control peptide for LSKL (leucine-serine-lysine-leucine).

GsMTx4 TFA

Reference: HY-P1410A

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GsMTx4 TFA is a spider venom peptide that selectively inhibits cationic-permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families. GsMTx4 TFA also blocks cation-selective...

Fmoc-L-b-methylisoleucine

Reference: HY-W039112

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Fmoc-L-b-methylisoleucine is an amino acid derivative that can be used for compound synthesis.

PE 22-28

Reference: HY-P3581

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PE 22-28 is a TREK-1 inhibitor with IC50 value of 0.12 nM. PE 22-28 also is a 7 amino-acid peptide that is used as a core sequence for preparing analogs by chemical modifications and also by substitution of...

SPAI-1

Reference: HY-P3711

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SPAI-1 is a specific inhibitor for monovalent cation transporting ATPases. SPAI-1 is a peptide isolated from porcine duodenum, inhibits Na+, K+-ATPase and H+, K+-ATPase in vitro, stimulates Mg2+-ATPase.

Histatin 5 TFA

Reference: HY-P0273A

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Histatin 5 TFA inhibits the activity of the host matrix metalloproteinases MMP-2 and MMP-9 with IC50s of 0.57 and 0.25 μM, respectively.

Adipokinetic Hormone (AKH) (24-32), locust

Reference: HY-P1456

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Adipokinetic Hormone (AKH) (24-32), locust, isolated from locust corpora cardiaca, is a neurohormone that regulates lipid utilisation during flight.

[Mpr7, DAla9] ANP (7-28), amide, rat

Reference: HY-P3772

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[Mpr7, DAla9] ANP (7-28), amide, rat is an atrial peptide.

Boc-Thr-OH

Reference: HY-W012437

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Boc-Thr-OH is a threonine derivative.

Adrenocorticotropic Hormone (ACTH) (1-39), rat TFA

Reference: HY-P1477A

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Adrenocorticotropic Hormone (ACTH) (1-39), rat (TFA) is a potent melanocortin 2 (MC2) receptor agonist.

BH3 hydrochloride

Reference: HY-P2343

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BH3 hydrochloride, a BBB penetrated peptide, provoke apoptosis either by direct activation of pro-apoptotic Bax/Bak or by neutralizing anti-apoptotic Bcl-2 proteins (Bcl-2, Bcl-XL, Bcl-w, Mcl-1 and A-1) via their BH3...

CRF(6-33)(human) TFA

Reference: HY-P1297A

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CRF(6-33)(human) TFA is a CRF binding protein (CRF-BP) ligand inhibitor. CRF(6-33)(human) TFA competitively binds the CRF-BP but not the post-synaptic CRF receptors. CRF(6-33)(human) TFA has anti-obesity effect.

Adrenocorticotropic Hormone (ACTH) (1-10), human

Reference: HY-P1518

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Adrenocorticotropic Hormone (ACTH) (1-10), human, an adrenocorticotropin hormone fragment, possesses a weak α-melanocyte stimulating hormone (α-MSH) potency only at high doses (100 and 1000 nM).

Phytochelatin 2 (PC2)

Reference: HY-P2512

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Phytochelatin 2, a short phytochelatin, is a key plant peptide binding heavy metals. Phytochelatins are a diverse set of plant compounds that chelate metals, protect against metal toxicity and function in metal...

Fmoc-D-3,3-diphenylalanine

Reference: HY-W008922

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Fmoc-D-3,3-diphenylalanine is a peptide derivative.

Gastrin I (1-14), human TFA

Reference: HY-P1806A

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Gastrin I (1-14), human TFA is 1-14 fragment of human gastrin I peptide. Gastrin I is an endogenous, gastrointestinal peptide hormone. Gastrin is the major hormonal regulator of gastric acid secretion.

Antitumor agent-39

Reference: HY-P3358

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Antitumor agent-39 is a peptide compound with anticancer effect (US20050009751A1, compound 64).

H-Met-OiPr hydrochloride

Reference: HY-W022657

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H-Met-OiPr hydrochloride is an Methionine derivative. H-Met-OiPr hydrochloride participates in the synthesis preparation of inhibitors of farnesyl-protein transferase (FTase), and can be used in cancer research.

CKLF1-C27

Reference: HY-P3418

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CKLF1-C27, a C-terminal peptide of CKLF1, binds to CCR4 receptor and activates ERK1/2 pathway. CKLF1-C27 can abrogate the effect of CKLF1 on cells by competing for CCR4 receptor. CKLF1-C27 shows great effect on...

Kyotorphin

Reference: HY-122381

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Kyotorphin is an endogenou neuroactive dipeptide with analgesic properties. Kyotorphin possesses anti-inflammatory and antimicrobial activity. Kyotorphin levels in cerebro-spinal fluid correlate negatively with the...

Enfuvirtide

Reference: HY-P0052

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Enfuvirtide (T20;DP178) is an anti-HIV-1 fusion inhibitor peptide.

Ac-D-DGla-LI-Cha-C

Reference: HY-P4040

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Ac-D-DGla-LI-Cha-C is a potent HCV protease inhibitor peptide. Ac-D-DGla-LI-Cha-C can be used for the research of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases,...

(R)-Phenylglycine tert-butyl ester hydrochloride

Reference: HY-W042009A

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(R)-Phenylglycine tert-butyl ester hydrochloride is a Glycine (HY-Y0966) derivative.

STAD 2

Reference: HY-P2261

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STAD 2 is a potent and selective disruptor of PKA-RII, with a Kd of 6.2 nM. STAD 2 disrupts interactions between PKA and AKAP in an isoform-selective manner. STAD 2 displays antimalarial activity through a...

[Ala9,10, Lys11,12] Glycogen Synthase (1-12)

Reference: HY-P3741

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[Ala9,10, Lys11,12] Glycogen Synthase (1-12) is a selective substrate for phosphorylation by protein kinase C (PKC). [Ala9,10, Lys11,12] Glycogen Synthase (1-12) can be used to determine the activity of protein kinase C.

Pro-Phe-Phe

Reference: HY-P2787

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Pro-Phe-Phe is the most aggregation-prone tripeptide of natural amino acids. Pro-Phe-Phe forms unique helical-like sheets that mate via aromatic dry interfaces. Pro-Phe-Phe can be used for the design of modular...

Cyclic SSTR agonist octreotide

Reference: HY-P4100

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Cyclic SSTR agonist octreotide is a Octreotide (HY-P0036), serving as the cyclic Somatostatin Receptor SSTR agonist.

PDZ1 Domain inhibitor peptide TFA

Reference: HY-P1195A

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PDZ1 Domain inhibitor peptide TFA, a cyclic peptide, incorporates a β-Ala lactam side chain linker and targets the PDZ1 domains of the postsynaptic density protein 95 (PSD-95). PDZ1 Domain inhibitor peptide TFA...

Poly-L-lysine hydrobromide (MW 70000-150000)

Reference: HY-126437B

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Poly-L-lysine (hydrobromide) (MW 70000-150000), a positively charged amino acid polymer, is a nonspecific attachment factor for cells. Poly-L-lysine (hydrobromide) (MW 70000-150000) has good biocompatibility....