ω-Agatoxin IVA

ω-Agatoxin IVA is a potent, selective P/Q type Ca2+ (Cav2.1) channel blocker with IC50s of 2 nM and 90 nM for P-type and Q-type Ca2+ channels, respectively. ω-Agatoxin IVA (IC50, 30-225 nM) inhibits glutamate exocytosis and calcium influx elicited by high potassium. ω-Agatoxin IVA also blocks the high potassium-induced release of serotonin and norepinephrine. ω-Agatoxin IVA has no effect on L-type or N-type calcium channels.
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Reference:
HY-P1080
Product Details
HY-P1080

Data sheet

Size
Multiple sizes
Reactivity
Calcium Channel
Application
Neuroscience-Neuromodulation
CAS
145017-83-0

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