Primary antibodies (2)

C3 antibody [C3], C-term

Reference: GRP102

€0.00 (tax incl.)

Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. People with C3 deficiency are...

ADAM17 antibody [C2C3], C-term

Reference: GRP103

€0.00 (tax incl.)

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been...

Iba1 antibody

Reference: GRP104

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This gene is induced by cytokines and interferon. Its protein product is thought to be involved in negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to...

SOX2 antibody [N1C3]

Reference: GRP105

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This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this...

Dopamine beta Hydroxylase antibody

Reference: GRP106

€0.00 (tax incl.)

The protein encoded by this gene is an oxidoreductase belonging to the copper type II, ascorbate-dependent monooxygenase family. It is present in the synaptic vesicles of postganglionic sympathetic neurons and...

GRK2 antibody [C2C3], C-term

Reference: GRP107

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The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme...

GAD67 antibody

Reference: GRP108

€0.00 (tax incl.)

This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of...

F4/80 antibody [C2C3], C-term

Reference: GRP109

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This gene encodes a protein that has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its C-terminus. The N-terminus of the encoded protein has six EGF-like modules,...

Tyrosine Hydroxylase antibody [N1C1]

Reference: GRP110

€0.00 (tax incl.)

The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic...

Islet 1 antibody

Reference: GRP111

€0.00 (tax incl.)

This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating...

HRH1 antibody

Reference: GRP112

€0.00 (tax incl.)

Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene was thought to be...

Homer1 antibody

Reference: GRP113

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This gene encodes a member of the homer family of dendritic proteins. Members of this family regulate group 1 metabotrophic glutamate receptor function. [provided by RefSeq]

NELL1 antibody

Reference: GRP114

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This gene encodes a cytoplasmic protein that contains epidermal growth factor (EGF)-like repeats. The encoded heterotrimeric protein may be involved in cell growth regulation and differentiation. A similar protein in...

OAT antibody [N1C3]

Reference: GRP115

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This gene encodes the mitochondrial enzyme ornithine aminotransferase, which is a key enzyme is the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and...

LDB1 antibody [N2C3]

Reference: GRP116

€0.00 (tax incl.)

Binds to the LIM domain of a wide variety of LIM domain-containing transcription factors. May regulate the transcriptional activity of LIM-containing proteins by determining specific partner interactions. May play a...

5-HT1A receptor antibody [N3C1], Internal

Reference: GRP117

€0.00 (tax incl.)

5-HT1A receptor antibody [N3C1], Internal

Monoamine Oxidase B antibody [N2C3]

Reference: GRP118

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The protein encoded by this gene belongs to the flavin monoamine oxidase family. It is a enzyme located in the mitochondrial outer membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and...

IL1 Receptor antagonist antibody

Reference: GRP119

€0.00 (tax incl.)

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of...

PKC gamma antibody

Reference: GRP120

€0.00 (tax incl.)

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein...

RBP1 antibody

Reference: GRP121

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This gene encodes the carrier protein involved in the transport of retinol (vitamin A alcohol) from the liver storage site to peripheral tissue. Vitamin A is a fat-soluble vitamin necessary for growth, reproduction,...

Opsin 3 antibody [N1], N-term

Reference: GRP122

€0.00 (tax incl.)

Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. In addition to the visual opsins, mammals possess several photoreceptive non-visual opsins that are expressed in...

MC1 Receptor antibody [C2C3], C-term

Reference: GRP123

€0.00 (tax incl.)

This intronless gene encodes the receptor protein for melanocyte-stimulating hormone (MSH). The encoded protein, a seven pass transmembrane G protein coupled receptor, controls melanogenesis. Two types of melanin...

GFAP antibody

Reference: GRP124

€0.00 (tax incl.)

This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause...

Glutamine synthetase antibody

Reference: GRP125

€0.00 (tax incl.)

Glutamine is a main source of energy and is involved in cell proliferation, inhibition of apoptosis, and cell signaling (Haberle et al., 2005 [PubMed 16267323]). Fetal glutamine requirements are very high and depend...

PGP9.5 antibody

Reference: GRP126

€0.00 (tax incl.)

UCHL1 is a member of a gene family whose products hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. Expression of UCHL1 is highly specific to neurons and to cells of the diffuse...

RAB5A antibody

Reference: GRP127

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RAB5A antibody

ALDH1A3 antibody [N2C2], Internal

Reference: GRP128

€0.00 (tax incl.)

Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The enzyme encoded by this gene uses retinal as a substrate,...

ATP6V1A antibody

Reference: GRP129

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This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such...

mAChR M3 antibody

Reference: GRP130

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The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses...

TRPM2 antibody [N1N2-2], N-term

Reference: GRP131

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The protein encoded by this gene is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death....

alpha Synuclein antibody

Reference: GRP132

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Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively....

C1qA antibody

Reference: GRP133

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This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been...

Choline Acetyltransferase antibody [N1N3]

Reference: GRP134

€0.00 (tax incl.)

This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some...

GAD67 antibody

Reference: GRP135

€0.00 (tax incl.)

This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of...

GAD65 antibody

Reference: GRP136

€0.00 (tax incl.)

This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of...

PAX6 antibody

Reference: GRP137

€0.00 (tax incl.)

This gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also...

Aspartoacylase antibody [N1C3-2]

Reference: GRP138

€0.00 (tax incl.)

This gene encodes an enzyme that catalyzes the conversion of N-acetyl_L-aspartic acid (NAA) to aspartate and acetate. NAA is abundant in the brain where hydrolysis by aspartoacylase is thought to help maintain white...

CBS antibody

Reference: GRP139

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The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by...

HPRT antibody

Reference: GRP140

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HPRT1 has a central role in the generation of purine nucleotides through the purine salvage pathway. HPRT1 catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via...

TDP43 antibody

Reference: GRP141

€0.00 (tax incl.)

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the...

GNB1 antibody

Reference: GRP142

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Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by...

MAFG antibody

Reference: GRP143

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Globin gene expression is regulated through nuclear factor erythroid-2 (NFE2) elements located in enhancer-like locus control regions positioned many kb upstream of alpha- and beta-gene clusters (summarized by Blank...

Brn2 antibody

Reference: GRP144

€0.00 (tax incl.)

POU3F2 belongs to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. Most of these proteins share a highly homologous region, referred to as the POU domain, that occurs in...

Ataxin 3 antibody

Reference: GRP145

€0.00 (tax incl.)

Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these...

ALDH1A2 antibody [C1C3]

Reference: GRP146

€0.00 (tax incl.)

This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative...

NPEPPS antibody [N3C2-2], Internal

Reference: GRP147

€0.00 (tax incl.)

This gene encodes the puromycin-sensitive aminopeptidase, a zinc metallopeptidase which hydrolyzes amino acids from the N-terminus of its substrate. The protein has been localized to both the cytoplasm and to cellular...

SIGMAR1 antibody [N1C3]

Reference: GRP148

€0.00 (tax incl.)

This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various...

CD45 antibody

Reference: GRP149

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The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth,...

Chromogranin C antibody

Reference: GRP150

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The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the...

ALDH1A1 antibody

Reference: GRP151

€0.00 (tax incl.)

This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme,...

ALDH1A1 antibody

Reference: GRP152

€0.00 (tax incl.)

This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme,...

DLK/MAP3K12 antibody

Reference: GRP153

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May be an activator of the JNK/SAPK pathway. Phosphorylates beta-casein, histone 1 and myelin basic protein in vitro.

SNAI1 antibody

Reference: GRP154

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The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally...

GABA antibody

Reference: GRP155

€0.00 (tax incl.)

GABA antibody

ASCL1 antibody

Reference: GRP156

€0.00 (tax incl.)

This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is...

VIP antibody

Reference: GRP157

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The protein encoded by this gene belongs to the glucagon family. It stimulates myocardial contractility, causes vasodilation, increases glycogenolysis, lowers arterial blood pressure and relaxes the smooth muscle of...

S100 beta antibody

Reference: GRP158

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The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and...

PER2 antibody

Reference: GRP159

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This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode...

beta Tubulin 3/ Tuj1 antibody

Reference: GRP160

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This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein...

Calbindin antibody

Reference: GRP161

€0.00 (tax incl.)

Calbindin is a calcium-binding protein belonging to the troponin C superfamily. It was originally described as a 27-kD protein induced by vitamin D in the duodenum of the chick. In the brain, its synthesis is...

BDNF antibody

Reference: GRP162

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The protein encoded by this gene is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in...

OLIG2 antibody

Reference: GRP163

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This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The...

NeuN antibody

Reference: GRP164

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NeuN antibody

PSD95 antibody

Reference: GRP165

€0.00 (tax incl.)

Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes...

Myelin basic Protein antibody

Reference: GRP166

€0.00 (tax incl.)

The protein encoded by the classic Mbp gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, Mbp-related transcripts are also present in the bone marrow...

MAP2 antibody

Reference: GRP167

€0.00 (tax incl.)

MAP2 antibody

NeuN antibody

Reference: GRP168

€0.00 (tax incl.)

RNA-binding protein that regulates alternative splicing events.

Parvalbumin antibody

Reference: GRP169

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In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

Ubiquitin antibody [GT751]

Reference: GRP170

€0.00 (tax incl.)

Ubiquitin antibody [GT751]

Ubiquitin antibody [GT7811]

Reference: GRP171

€0.00 (tax incl.)

Ubiquitin antibody [GT7811]

TDP43 antibody [GT225]

Reference: GRP172

€0.00 (tax incl.)

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the...

Glutamine synthetase antibody [GT1055]

Reference: GRP173

€0.00 (tax incl.)

Glutamine is a main source of energy and is involved in cell proliferation, inhibition of apoptosis, and cell signaling (Haberle et al., 2005 [PubMed 16267323]). Fetal glutamine requirements are very high and depend...

beta Tubulin 3/ Tuj1 antibody [GT11710]

Reference: GRP174

€0.00 (tax incl.)

This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein...

Iba1 antibody [GT10312]

Reference: GRP175

€0.00 (tax incl.)

This gene is induced by cytokines and interferon. Its protein product is thought to be involved in negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to...

LAMP1 antibody [GT25212]

Reference: GRP176

€0.00 (tax incl.)

The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. [provided by RefSeq]

IL1 beta antibody

Reference: GRP177

€0.00 (tax incl.)

IL1 beta antibody

Cytochrome C Polyclonal Antibody

Reference: GRP178

€0.00 (tax incl.)

Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to...

IGF 1 Polyclonal Antibody

Reference: GRP179

€0.00 (tax incl.)

The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of...

Tyrosine Hydroxylase Polyclonal Antibody

Reference: GRP180

€0.00 (tax incl.)

Neuronal Marker Tyrosine hydroxylase is involved in the conversion of tyrosine to dopamine. As the rate-limiting enzyme in the synthesis of catecholamines, tyrosine hydroxylase has a key role in the physiology of...

Osteopontin Polyclonal Antibody

Reference: GRP181

€0.00 (tax incl.)

Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity (By similarity).

ERK1 + ERK2 Polyclonal Antibody

Reference: GRP182

€0.00 (tax incl.)

Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They...

Presenilin 1 Polyclonal Antibody

Reference: GRP183

€0.00 (tax incl.)

Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor...

Melatonin Receptor 1A Antibody

Reference: GRP184

€0.00 (tax incl.)

High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate...

GSK-3 Beta Polyclonal Antibody

Reference: GRP185

€0.00 (tax incl.)

The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation....

P53 protein(wt-p53) Polyclonal Antibody

Reference: GRP186

€0.00 (tax incl.)

Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to...

CREB-1 Polyclonal Antibody

Reference: GRP187

€0.00 (tax incl.)

Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is...

CREB-1(Ser133) Polyclonal Antibody

Reference: GRP188

€0.00 (tax incl.)

Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is...

AIF Polyclonal Antibody

Reference: GRP189

€0.00 (tax incl.)

Functions both as NADH oxidoreductase and as regulator of apoptosis. In response to apoptotic stimuli, it is released from the mitochondrion intermembrane space into the cytosol and to the nucleus, where it functions...

Neurokinin 1 Receptor Antibody

Reference: GRP190

€0.00 (tax incl.)

This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this...

Neurturin Polyclonal Antibody

Reference: GRP191

€0.00 (tax incl.)

Supports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS. Might control the size of non-neuronal cell population such as haemopoietic cells.

CD19 Polyclonal Antibody

Reference: GRP192

€0.00 (tax incl.)

Assembles with the antigen receptor of B-lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.

Caspase 3 Polyclonal Antibody

Reference: GRP193

€0.00 (tax incl.)

Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and...

TGF beta 1 Polyclonal Antibody

Reference: GRP194

€0.00 (tax incl.)

Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many...

Calponin 1 Polyclonal Antibody

Reference: GRP195

€0.00 (tax incl.)

Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin...

TGF beta 2 Propeptide Antibody

Reference: GRP196

€0.00 (tax incl.)

Transforming Growth Factor (TGF) betas mediate many cell to cell interactions that occur during embryonic development. Three TGF betas have been identified in mammals. TGF beta 1, TGF beta 2 and TGF beta 3 are each...

AKT1/2/3 Polyclonal Antibody

Reference: GRP197

€0.00 (tax incl.)

AKT1-specific substrates have been recently identified, including palladin (PALLD), which phosphorylation modulates cytoskeletal organization and cell motility; prohibitin (PHB), playing an important role in cell...

Estrogen receptor beta Antibody

Reference: GRP198

€0.00 (tax incl.)

Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. Isoform...

TGF beta R2 Polyclonal Antibody

Reference: GRP199

€0.00 (tax incl.)

Transmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1,...

Androgen receptor Polyclonal Antibody

Reference: GRP200

€0.00 (tax incl.)

Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is...

HSP70 Polyclonal Antibody

Reference: GRP201

€0.00 (tax incl.)

In cooperation with other chaperones, Hsp7s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones...

Category: Primary antibodies

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