Primary antibodies (4)

CD4 Polyclonal Antibody

Reference: GRP302

€0.00 (tax incl.)

Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation.

IL-12 alpha Polyclonal Antibody

Reference: GRP303

€0.00 (tax incl.)

Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC.

FSCN1(Ser39) Polyclonal Antibody

Reference: GRP304

€0.00 (tax incl.)

Organizes filamentous actin into bundles with a minimum of 4.1:1 actin/fascin ratio. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers....

ECM1 Polyclonal Antibody

Reference: GRP305

€0.00 (tax incl.)

Involved in endochondral bone formation as negative regulator of bone mineralization. Stimulates the proliferation of endothelial cells and promotes angiogenesis. Inhibits MMP9 proteolytic activity (By similarity).

Thy-1 Polyclonal Antibody

Reference: GRP306

€0.00 (tax incl.)

May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.

IL-6 Polyclonal Antibody

Reference: GRP307

€0.00 (tax incl.)

Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte...

RSL1D1 Polyclonal Antibody

Reference: GRP308

€0.00 (tax incl.)

Regulates cellular senescence through inhibition of PTEN translation. Acts as a pro-apoptotic regulator in response to DNA damage.

CD56 Polyclonal Antibody

Reference: GRP309

€0.00 (tax incl.)

This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.

Fibulin 5 Polyclonal Antibody

Reference: GRP310

€0.00 (tax incl.)

Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Could be a vascular ligand for integrin receptors and may play a role in vascular development and remodeling.

CX3CL1 Polyclonal Antibody

Reference: GRP311

€0.00 (tax incl.)

The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion...

IL-1 Beta Polyclonal Antibody

Reference: GRP312

€0.00 (tax incl.)

Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the...

Thrombin receptor Polyclonal Antibody

Reference: GRP313

€0.00 (tax incl.)

High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.

Nanog Polyclonal Antibody

Reference: GRP314

€0.00 (tax incl.)

Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and...

APOA1 Polyclonal Antibody

Reference: GRP315

€0.00 (tax incl.)

Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase...

AKT1/2/3 (Ser472/Ser473/Ser474) Antibody

Reference: GRP316

€0.00 (tax incl.)

AKT1-specific substrates have been recently identified, including palladin (PALLD), which phosphorylation modulates cytoskeletal organization and cell motility; prohibitin (PHB), playing an important role in cell...

VE Cadherin Polyclonal Antibody

Reference: GRP317

€0.00 (tax incl.)

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell...

FSH receptor Polyclonal Antibody

Reference: GRP318

€0.00 (tax incl.)

Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.

Acetyl p53(K382) Polyclonal Antibody

Reference: GRP319

€0.00 (tax incl.)

Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to...

SIRT1 Polyclonal Antibody

Reference: GRP320

€0.00 (tax incl.)

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions...

Neurogenin 3 Polyclonal Antibody

Reference: GRP321

€0.00 (tax incl.)

Acts as a transcriptional regulator. Together with NKX2-2, initiates transcriptional activation of NEUROD1. Involved in neurogenesis. Also required for the specification of a common precursor of the 4 pancreatic...

ADRB2 Polyclonal Antibody

Reference: GRP322

€0.00 (tax incl.)

Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 3-fold greater...

Collagen 3 Polyclonal Antibody

Reference: GRP323

€0.00 (tax incl.)

Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of GPR56 in the developing brain and binding to GPR56 inhibits...

Leptin receptor Polyclonal Antibody

Reference: GRP324

€0.00 (tax incl.)

Receptor for obesity factor (leptin). On ligand binding, mediates signaling through JAK2/STAT3. Involved in the regulation of fat metabolism and, in a hematopoietic pathway, required for normal lymphopoiesis. May play...

CD38 Polyclonal Antibody

Reference: GRP325

€0.00 (tax incl.)

Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity (By similarity).

NFKB p65(Ser536) Polyclonal Antibody

Reference: GRP326

€0.00 (tax incl.)

NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological...

EAAT1 Polyclonal Antibody

Reference: GRP327

€0.00 (tax incl.)

Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting...

DRD1 Polyclonal Antibody

Reference: GRP328

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Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.

DRD2 Polyclonal Antibody

Reference: GRP329

€0.00 (tax incl.)

Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase.

CXCR1 Polyclonal Antibody

Reference: GRP330

€0.00 (tax incl.)

Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a...

CXCR4 Polyclonal Antibody

Reference: GRP331

€0.00 (tax incl.)

Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to...

BMP2 Polyclonal Antibody

Reference: GRP332

€0.00 (tax incl.)

BMP2 belongs to the transforming growth factor-beta (TGFB) superfamily of secreted growth factors. It is a disulfide-linked homodimer and induces bone and cartilage formation. In addition to its osteogenic activity,...

CD11b/c Polyclonal Antibody

Reference: GRP333

€0.00 (tax incl.)

Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the...

TLR2 Polyclonal Antibody

Reference: GRP334

€0.00 (tax incl.)

Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial...

GDNF Polyclonal Antibody

Reference: GRP335

€0.00 (tax incl.)

Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.

Desmin Polyclonal Antibody

Reference: GRP336

€0.00 (tax incl.)

Desmin are class-III intermediate filaments found in muscle cells. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line...

NSE Polyclonal Antibody

Reference: GRP337

€0.00 (tax incl.)

Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival (By...

Inhibin Alpha Polyclonal Antibody

Reference: GRP338

€0.00 (tax incl.)

Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and...

CHRNA4 Polyclonal Antibody

Reference: GRP339

€0.00 (tax incl.)

After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodium ions.

MyD88 Polyclonal Antibody

Reference: GRP340

€0.00 (tax incl.)

Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the...

Podoplanin Polyclonal Antibody

Reference: GRP341

€0.00 (tax incl.)

May be involved in cell migration and/or actin cytoskeleton organization. When expressed in keratinocytes, induces changes in cell morphology with transfected cells showing an elongated shape, numerous membrane...

CHRNA7 Polyclonal Antibody

Reference: GRP342

€0.00 (tax incl.)

After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is blocked by...

5-HTR2 Polyclonal Antibody

Reference: GRP343

€0.00 (tax incl.)

G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including mescaline, psilocybin,...

Integrin Alpha 3 + Beta 1 Antibody

Reference: GRP344

€0.00 (tax incl.)

alpha3beta1 integrin is a laminin receptor with apparently diverse functions. In epithelial cells it acts as a receptor for the basement membrane, whereas in neuronal and possibly tumor cells it mediates migration....

beta 3 Adrenergic Receptor Antibody

Reference: GRP345

€0.00 (tax incl.)

Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis.

KLF2/4 Polyclonal Antibody

Reference: GRP346

€0.00 (tax incl.)

Transcription factor; can act both as activator and as repressor. Binds the 5'-CACCC-3' core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of...

Nrf2 Polyclonal Antibody

Reference: GRP347

€0.00 (tax incl.)

Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved...

NADPH oxidase 4 Polyclonal Antibody

Reference: GRP348

€0.00 (tax incl.)

Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen...

SKP2 Polyclonal Antibody

Reference: GRP349

€0.00 (tax incl.)

Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle...

PAX3 Polyclonal Antibody

Reference: GRP350

€0.00 (tax incl.)

Transcription factor that may regulate cell proliferation, migration and apoptosis. Involved in neural development and myogenesis.

Calpain 1 Polyclonal Antibody

Reference: GRP351

€0.00 (tax incl.)

Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.

Caspase 12 Polyclonal Antibody

Reference: GRP352

€0.00 (tax incl.)

Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory...

Osterix Polyclonal Antibody

Reference: GRP353

€0.00 (tax incl.)

Transcriptional activator essential for osteoblast differentiation. Binds to SP1 and EKLF consensus sequences and to other G/C-rich sequences (By similarity).

Oct-4 Polyclonal Antibody

Reference: GRP354

€0.00 (tax incl.)

Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4,...

AMPK alpha-1 Polyclonal Antibody

Reference: GRP355

€0.00 (tax incl.)

The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all...

SGLT1 Polyclonal Antibody

Reference: GRP356

€0.00 (tax incl.)

Actively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high...

SNAP25 Polyclonal Antibody

Reference: GRP357

€0.00 (tax incl.)

t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and...

EDA Polyclonal Antibody

Reference: GRP358

€0.00 (tax incl.)

Seems to be involved in epithelial-mesenchymal signaling during morphogenesis of ectodermal organs. Isoform 1 binds only to the receptor EDAR, while isoform 3 binds exclusively to the receptor XEDAR.

ATP1b2/Na+K+ATPase Polyclonal Antibody

Reference: GRP359

€0.00 (tax incl.)

This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-2 subunit is...

ADFP Polyclonal Antibody

Reference: GRP360

€0.00 (tax incl.)

Milk lipid globules from humans, cows and rats contain a protein identified as adipocyte differentiation-related protein (ADFP) associated with the globule surface membrane material. This protein, previously believed...

Beta catenin Polyclonal Antibody

Reference: GRP361

€0.00 (tax incl.)

Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and...

ROCK1 Polyclonal Antibody

Reference: GRP362

€0.00 (tax incl.)

Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite...

N-cadherin Polyclonal Antibody

Reference: GRP363

€0.00 (tax incl.)

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell...

IL-17 Polyclonal Antibody

Reference: GRP364

€0.00 (tax incl.)

Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts.

CD14 Polyclonal Antibody

Reference: GRP365

€0.00 (tax incl.)

In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the MD-2/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6,...

NFkB p105 / p50 Polyclonal Antibody

Reference: GRP366

€0.00 (tax incl.)

NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological...

TRADD Polyclonal Antibody

Reference: GRP367

€0.00 (tax incl.)

Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced...

ROCK2 Polyclonal Antibody

Reference: GRP368

€0.00 (tax incl.)

Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite...

GLI1 Polyclonal Antibody

Reference: GRP369

€0.00 (tax incl.)

Acts as a transcriptional activator. May regulate the transcription of specific genes during normal development. May play a role in craniofacial development and digital development, as well as development of the...

GRP78 Polyclonal Antibody

Reference: GRP370

€0.00 (tax incl.)

Probably plays a role in facilitating the assembly of multimeric protein complexes inside the endoplasmic reticulum. Involved in the correct folding of proteins and degradation of misfolded proteins via its...

SHP-2/PTPN11 Polyclonal Antibody

Reference: GRP371

€0.00 (tax incl.)

Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation...

AQP3 Polyclonal Antibody

Reference: GRP372

€0.00 (tax incl.)

Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal...

E-Selectin/CD62E Polyclonal Antibody

Reference: GRP373

€0.00 (tax incl.)

Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with PSGL1/SELPLG. May have a role in capillary...

HLA E Polyclonal Antibody

Reference: GRP374

€0.00 (tax incl.)

HLA E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA E...

ASPP2/p53BP2 Polyclonal Antibody

Reference: GRP375

€0.00 (tax incl.)

Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic...

BAK Polyclonal Antibody

Reference: GRP376

€0.00 (tax incl.)

In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti-apoptotic action of BCL2.

NFKBIA/IKB alpha Polyclonal Antibody

Reference: GRP377

€0.00 (tax incl.)

Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses,...

GDF8/MSTN Polyclonal Antibody

Reference: GRP378

€0.00 (tax incl.)

The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is...

Syndecan 1 Polyclonal Antibody

Reference: GRP379

€0.00 (tax incl.)

Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix.

LYVE-1 Polyclonal Antibody

Reference: GRP380

€0.00 (tax incl.)

Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface...

Oxytocin R Polyclonal Antibody

Reference: GRP381

€0.00 (tax incl.)

Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.

ZO-1 Polyclonal Antibody

Reference: GRP382

€0.00 (tax incl.)

The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing...

BCL2L1 Polyclonal Antibody

Reference: GRP383

€0.00 (tax incl.)

Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase...

Tp73 protein Polyclonal Antibody

Reference: GRP384

€0.00 (tax incl.)

Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating...

FAF1 Polyclonal Antibody

Reference: GRP385

€0.00 (tax incl.)

Potentiates but cannot initiate FAS-induced apoptosis.

Beclin 1 Polyclonal Antibody

Reference: GRP386

€0.00 (tax incl.)

Plays a central role in autophagy. Required for the abcission step in cytokinesis. May play a role in antiviral host defense. Protects against infection by a neurovirulent strain of Sindbis virus.

Apolipoprotein J Polyclonal Antibody

Reference: GRP387

€0.00 (tax incl.)

Isoform 1 functions as extracellular chaperone that prevents aggregation of nonnative proteins. Prevents stress-induced aggregation of blood plasma proteins. Inhibits formation of amyloid fibrils by APP, APOC2, B2M,...

GADD45 Polyclonal Antibody

Reference: GRP388

€0.00 (tax incl.)

In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity (By similarity). Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA...

Tsg101 Polyclonal Antibody

Reference: GRP389

€0.00 (tax incl.)

Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies...

GPR30 Polyclonal Antibody

Reference: GRP390

€0.00 (tax incl.)

G-protein coupled estrogen receptor that binds to 17-beta-estradiol (E2) with high affinity, leading to rapid and transient activation of numerous intracellular signaling pathways. Stimulates cAMP production, calcium...

SLUG Polyclonal Antibody

Reference: GRP391

€0.00 (tax incl.)

Transcriptional repressor that modulates both activator-dependent and basal transcription. Involved in the generation and migration of neural crest cells. Plays a role in mediating RAF1-induced transcriptional...

CHK2 Polyclonal Antibody

Reference: GRP392

€0.00 (tax incl.)

Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest, activation of DNA repair and apoptosis in response to the presence of DNA double-strand breaks. May also negatively regulate...

SREBP-1/2 Polyclonal Antibody

Reference: GRP393

€0.00 (tax incl.)

Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the fatty acid and to a lesser degree the cholesterol synthesis pathway. Binds to the sterol...

MC-1R/MC1 Receptor Polyclonal Antibody

Reference: GRP394

€0.00 (tax incl.)

Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.

EPOR Polyclonal Antibody

Reference: GRP395

€0.00 (tax incl.)

Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can...

Claudin 1 Polyclonal Antibody

Reference: GRP396

€0.00 (tax incl.)

Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members play essential roles in the formation of impermeable barriers,...

CXCL16 Polyclonal Antibody

Reference: GRP397

€0.00 (tax incl.)

Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo. Also acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein),...

HIF2 alpha Polyclonal Antibody

Reference: GRP398

€0.00 (tax incl.)

Transcription factor involved in the induction of oxygen regulated genes. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. Regulates the vascular...

Prohibitin Polyclonal Antibody

Reference: GRP399

€0.00 (tax incl.)

Prohibitin inhibits DNA synthesis. It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. May play a role in regulating mitochondrial respiration activity and...

Caveolin-1 Polyclonal Antibody

Reference: GRP400

€0.00 (tax incl.)

May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential...

Adenosine A2a receptor Antibody

Reference: GRP401

€0.00 (tax incl.)

This gene encodes a protein which is one of several receptor subtypes for adenosine. The activity of the encoded protein, a G protein coupled receptor family member, is mediated by G proteins which activate adenylyl...

Category: Primary antibodies

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