ZWINT antibody [GT276]

This gene encodes a protein that is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW1, another kinetochore protein, possibly regulating the association between ZW1 and kinetochores. The encoded protein localizes to prophase kinetochores before ZW1 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]