Phospho IGF1 Receptor Antibody Duo (Total, pY1161)

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
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Reference:
ARG30240
Product Details
ARG30240

Data sheet

Size
1 pair
URL - Product
https://www.arigobio.com/download/datasheet/ARG30240.pdf

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