Rb antibody

The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq]
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Reference:
GRP11
Brand:
Product Details
GRP11

Data sheet

Size
100 ul
Conjugation
Unconjugated
Host
Rabbit
Clonality
Polyclonal
Reactivity
Human,Mouse
Application
ICC,IF,IHC-P,IP,WB

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