BRCA1 antibody [6B4] - ChIP grade

BRCA1-6B4 recognizes full length BRCA1, a 220kDa nuclear phosphoprotein, and does not recognize the exon 11 splice variant. Mutations in this tumor suppressor gene greatly increase the risk of breast cancer. In a high proportion of breast and ovarian cancer cell lines, BRCA1 aberrantly mislocates to the cytoplasm. Recent studies suggest a role for BRCA1 in DNA double strand break repair because of its association with Rad51.
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Reference:
GRP86
Brand:
Product Details
GRP86

Data sheet

Size
100 ul
Conjugation
Unconjugated
Host
Mouse
Clonality
Monoclonal
Reactivity
Human,Mouse
Clone
6B4
Application
ChIP,ICC,IF,IHC-P,IP,WB

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