PI3 kinase p85 alpha subunit Antibody

Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p11 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.
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Reference:
GRP204
Brand:
Product Details
GRP204

Data sheet

Size
100 ul
Conjugation
Unconjugated
Host
Rabbit
Clonality
Polyclonal
Reactivity
Human,Mouse,Rat
Application
FC,ICC,IF,IHC-P,WB

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