[KO Validated] IGF1R Rabbit pAb

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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Reference:
A0243
Brand:
Product Details
A0243

Data sheet

Size
Various formats
Conjugation
Unconjugated
Host
Rabbit
Reactivity
Human,Mouse,Rat
Application
WB
CAS
https://abclonal.com/instructions/pdf/A0243

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