Ontorpacept

Ontorpacept (TTI-621) is a soluble fusion protein that consists of the human SIRPα N-terminal (1-118) linked to the Fc region of human IgG1. The N-terminal (1-118)-fragment of ontorpacept is a binding domain for CD47 which is an inhibitor of phagocytosis by macrophages. Ontorpacept is a CD47-blocking checkpoint inhibitor with antitumor activity.
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Reference:
HY-P99777
Product Details
HY-P99777

Data sheet

Size
Multiple sizes
Reactivity
Others
CAS
2131089-46-6

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