SMAD3 Polyclonal Antibody

Immunogen: Portion of amino acids 100-150 of human SMAD3 • Host: Rabbit • Cross Reactivity: (+) Human, bovine, canine, mouse, porcine, primate, and rat • Application(s): IF, IHC, and WB • SMAD3 is a receptor-regulated SMAD (R-SMAD) that functions downstream of TGF-β and activin receptors and mediates their signaling. It is recruited by SARA (SMAD anchor for receptor activation) to the receptor kinase for phosphorylation. Upon phosphorylation it plays role in cell proliferation, differentiation, apoptosis and formation of ECM.
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Reference:
10832-100
Product Details
10832-100

Data sheet

Size
1 kit
Host
Rabbit
Application
IF, IHC, and WB
URL - Product
http://www.caymanchem.com/pdfs/10832.pdf

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