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Quote TRAF5 Monoclonal Antibody (Clone 55A219)
Antigen: fusion protein corresponding to amino acids 77-186 of human TRAF5 • Host: mouse • Cross Reactivity: (+) human and mouse TRAF5 • Application(s): WB • TRAF5, an adaptor protein that mediates signal transduction from TNF receptors, is implicated in NF-kB and c-Jun NH(2)-terminal kinase/stress-activated protein kinase activation by members of the TNF receptor superfamily, including CD27, CD30, CD40, and lymphotoxin-β receptor. Targeted disruption of TRAF5 gene causes defects in CD40-CD27 mediated lymphocyte activation.
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Reference:
10873-1
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