2′-Deoxy-2′-fluoroadenosine

2′-Deoxy-2′-fluoroadenosine can be used for the synthesis of 2′-Deoxy-2′-fluoro-modified oligonucleotides hybridized with RNA. 2′-Deoxy-2′-fluoroadenosine can be cleaved efficiently by E. coli purine nucleoside phosphorylase (PNP) to the toxic agent 2-fluoroadenine (FAde). 2′-Deoxy-2′-fluoroadenosine shows excellent in vivo activity against tumors expressing E. coli PNP.
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Reference:
HY-W039442
Product Details
HY-W039442

Data sheet

Size
Multiple sizes
Reactivity
Nucleoside Antimetabolite/Analog
Application
Cancer-programmed cell death
CAS
64183-27-3

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