TRAIL-R1 (human):Fc (human) (rec.)

TRAIL-R1 (DR4; CD261) is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.
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Reference:
AG-40B-0070-C050
Brand:
Product Details
AG-40B-0070-C050

Data sheet

Size
50 ug
Host
HEK 293 cells
URL - Product
https://www.adipogen.com/productmanagement/resource/download/type/sheet/id/13808

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