Recombinant Human MSP - 10 µg

Macrophage-stimulating protein (MSP), also known as hepatocyte growth factor-like, is serum protein with homology to hepatocyte growth factor (HGF).1 MSP is a soluble cytokine that belongs to the family of the plasminogen-related growth factors (PRGFs). PRGFs are alpha/beta heterodimers that bind to transmembrane tyrosine kinase receptors. Through binding to its receptor, MSP stimulates dissociation of epithelia and works as an inflammatory mediator by repressing the production of nitric oxide (NO).2 MSP exerts proliferative and antiapoptotic effects, suggesting that it may play a role in tubular regeneration after acute kidney injury.3