Recombinant Human IkB-alpha/NFKBIA Protein

This protein is a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The protein is interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.
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Reference:
RP00032
Brand:
Abclonal
Product Details
RP00032

Data sheet

Size
Various formats
Host
E. Coli
Reactivity
Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water.
CAS
https://abclonal.com/instructions/pdf/RP00032

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