Active Recombinant Human R-spondin-1 Protein

This protein is a secreted activator protein with two cysteine-rich, furin-like domains and one thrombospondin type 1 domain. The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects.
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Reference:
RP00071
Brand:
Abclonal
Product Details
RP00071

Data sheet

Size
Various formats
Host
HEK293 cells
Reactivity
Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water.
CAS
https://abclonal.com/instructions/pdf/RP00071

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