Heptelidic acid

Antibiotic. Potent selective glyceraldehyde 3-phosphate dehydrogenase (GAPDH) inhibitor. Binds to the essential Cys149 residue in the catalytic site of GADPH. Anticancer compound. Selectively kills high-glycolytic cancer cells through glucose-dependent active ATP deprivation. Antimalarial. Apoptosis inhibitor. DNA fragmentation and caspase-3 activation inhibitor. Selective and competitive inhibitor of mammalian DNA polymerases beta, lambda and terminal deoxynucleotidyl transferase (TdT) in family X of pols.
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Reference:
AG-CN2-0118-C250
Brand:
Product Details
AG-CN2-0118-C250

Data sheet

Size
250 ug
Host
Isolated from Trichoderma sp.
CAS
57710-57-3
URL - Product
https://www.adipogen.com/productmanagement/resource/download/type/sheet/id/11983

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