Z-VAD-FMK (Cell permeable)

Cell permeable, non-selective broad-spectrum caspase inhibitor. Binds irreversibly to the catalytic site of caspase proteases. The peptide is O-methylated in the P1 position on aspartic acid, providing enhanced stability and increased cell permeability. Inhibits ICE-family protease/caspase processing, leading to apoptosis and autophagy induction. Decreases proteasome activity. Potent inhibitor of caspase-1 activation in NLRP3/NALP3-induced cells. Used in apoptosis and inflammasome studies.
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Reference:
AG-CP3-0002-M005
Brand:
Product Details
AG-CP3-0002-M005

Data sheet

Size
5 mg
Host
Synthetic.
CAS
187389-52-2 and 634911-81-2
URL - Product
https://www.adipogen.com/productmanagement/resource/download/type/sheet/id/11498

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