Lysosomal Acid Lipase Activity MaxSpec® Assay Kit

Cayman's LAL Activity MaxSpec® Assay Kit includes the necessary reagents to quantify lysosomal acid lipase (LAL) activity in dried blood spots. The LAL Activity MaxSpec® Assay Substrate (P-PMHC) has been designed to function as a highly selective substrate for LAL, which hydrolyzes the fatty acyl group of P-PMHC resulting in the formation of the LAL Activity MaxSpec® Assay Product 4-propyl-8-methyl-7-hydroxycoumarin (PMHC). Using the LAL Activity MaxSpec® Assay Kit, LAL activity may be quantified directly by fluorometry or by LC-MS in combination with the LAL Activity MaxSpec® Assay Internal Standard. ,