Category: Research kits

Reference: 10004380-96
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Cayman’s PAF-AH Inhibitor Screening Assay uses 2-thio PAF as a substrate for PAF-AH. Upon hydrolysis of the acetyl thioester bond at the sn-2 position by PAF-AH, free thiols are detected using DTNB also known as...
Reference: 10004883-96
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The sPLA2 (Type V) Inhibitor Screening Assay is a convenient colorimetric assay designed for rapid screening of Type V sPLA2 inhibitors in a 96-well format. Each kit contains assay buffer, DTNB, diheptanoyl thio-PC,...
Reference: 10005020-96
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Cayman’s Protein Carbonyl Colorimetric Assay is a colorimetric assay for the measurement of oxidized proteins. The carbonyls of protein samples are derivatized using 2,4-dinitrophenylhydrazine. Formation of a Schiff...
Reference: 10005196-96
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FAAH is a cytosolic serine hydrolase responsible for the degradation of fatty acid amides, including AEA. Finding inhibitors to FAAH could offer a beneficial approach toward the treatment of pain, obesity, and various...
Reference: 10005292-1
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Contains SOAT-1/ACAT-1 polyclonal antibody and blocking peptide, cholesteryl linoleate hydroperoxides, POV-PC, and PGPC
Reference: 10006270-96
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Cayman’s Renin Inhibitor Screening Assay provides a convenient assay in a 96-well format for evaluating human renin inhibitors. The assay utilizes a renin-based synthetic peptide substrate which incorporates the...
Reference: 10006438-2
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Cayman’s Myeloperoxidase Chlorination Fluorometric Assay provides a convenient fluorescence-based method for detecting the MPO chlorination activity in both crude cell lysates and purified enzyme preparations. The...
Reference: 10006515-96
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Cayman’s HAT Inhibitor Screening Assay provides a fast, fluorescence-based method for evaluating PCAF HAT inhibitors. The procedure requires only three easy steps, all performed in the same microplate. In the first...
Reference: 10006518-1
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Cayman’s S-Nitrosylated Protein Detection Kit (Biotin Switch) employs a modification of the Jaffrey et al. 'Biotin-switch' method to allow for the direct visualization of S-nitrosylated proteins in whole cells or...
Reference: 10006855-96
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PPARs are ligand-activated transcription factors belonging to the large superfamily of nuclear receptors. PPARα primarily activates genes encoding proteins involved in fatty acid oxidation, while PPARγ primarily...
Reference: 10006908-1
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Cayman’s Adipogenesis Assay provides the reagents required for studying the induction and inhibition of adipogenesis in the established 3T3-L1 model, using the adipogenesis induction procedure. This kit can also be...
Reference: 10006910-96
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The HIF (hypoxia-inducible factor) transcription factor is a member of the basic-helix-loop-helix (bHLH) family of transcription factors and plays an important role in maintaining cellular oxygen homeostasis. HIF-1α...
Reference: 10006912-96
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The NF-κB/Rel family of transcription factors is comprised of several structurally-related proteins that form homodimers and heterodimers and include p50/p105, p52/p100, RelA (p65), and c-Rel/NF-κB. Acting as dimers,...
Reference: 10006914-96
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PPARs are ligand-activated transcription factors belonging to the large superfamily of nuclear receptors. PPARα primarily activates genes encoding proteins involved in fatty acid oxidation, while PPARγ primarily...
Reference: 10006915-96
€0.00 (tax incl.)
PPARs are ligand-activated transcription factors belonging to the large superfamily of nuclear receptors. PPARα primarily activates genes encoding proteins involved in fatty acid oxidation, while PPARγ primarily...
Reference: 10007640-96
€0.00 (tax incl.)
Cholesterol, particularly in the form of LDLs, is well understood to be associated with increased risk of coronary heart disease. The measurement of cholesterol is one of the most common tests performed in the...
Reference: 10007640-480
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Cholesterol, particularly in the form of LDLs, is well understood to be associated with increased risk of coronary heart disease. The measurement of cholesterol is one of the most common tests performed in the...
Reference: 10007685-384
€0.00 (tax incl.)
Cayman’s PPARγ FP-Based Ligand Screening Assay - Green provides a convenient fluorescence polarization (FP)-based single step assay for screening PPARγ ligands. In this assay, a ligand of PPARγ was conjugated to FITC...
Reference: 10007819-96
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SREBP-2 is a transcription factor that performs a critical role in the transcriptional regulation of genes involved in cholesterol synthesis and uptake including HMG-CoA synthase, HMG-CoA reductase, and the LDL receptor.
Reference: 10007889-96
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The NF-κB/Rel family of transcription factors is comprised of several structurally-related proteins that form homodimers and heterodimers and include p50/p105, p52/p100, RelA (p65), and c-Rel/NF-κB. Acting as dimers,...
Reference: 10007892-96
€0.00 (tax incl.)
Cayman’s TrxR Assay provides a convenient method for quantifying mammalian TrxR activity from tissue homogenates and cell lysates in a colorimetric 96-well plate format. In this assay, TrxR uses NADPH to reduce DTNB...
Reference: 10008041-1
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The 20S proteasome is the proteolytic core of a large protein degradation complex, the 26S proteasome. Proteasome inhibitors exhibit anti-inflammatory and antiproliferative effects, evidence that the proteasome may be...
Reference: 10008878-96
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PPARs are ligand-activated transcription factors belonging to the large superfamily of nuclear receptors. PPARα primarily activates genes encoding proteins involved in fatty acid oxidation, while PPARγ primarily...
Reference: 10008883-96
€0.00 (tax incl.)
Cayman’s WST-1 Proliferation Assay is based on the reduction of tetrazolium salt WST-1 to a soluble formazan dye by electron transport across the plasma membrane of dividing cells. This kit will also allow...
Reference: 10008883-480
€0.00 (tax incl.)
Cayman’s WST-1 Proliferation Assay is based on the reduction of tetrazolium salt WST-1 to a soluble formazan dye by electron transport across the plasma membrane of dividing cells. This kit will also allow...
Reference: 10009055-96
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Oxidative stress in the cellular environment results in the formation of highly reactive and unstable lipid hydroperoxides. Decomposition of the unstable peroxides derived from PUFAs results in the formation of...
Reference: 10009135-96
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Cayman’s Caspase-3/7 Fluorescence Assay Kit employs a specific substrate, N-Ac-DEVD-N’-MC-R110, which upon cleavage by active caspase-3 or caspase-7, generates a highly fluorescent product that can be measured using...
Reference: 10009172-100
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Mitochondrial membrane potential, (ΔψM), is an important parameter of mitochondrial function used as an indicator of cell health. JC-1 is a lipophilic, cationic dye that can selectively enter into mitochondria and...
Reference: 10009325-2
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Cayman’s Malachite Green Phosphate Assay provides a fast, reproducible, colorimetric method for measuring inorganic free phosphate in aqueous solutions. The assay method is based on the formation of a complex between...
Reference: 10009349-100
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Cayman’s Cell Cycle Phase Determination provides an easy to use tool for studying the induction and inhibition of cell cycle progression in any cell suspension sample. The assay involves the fixation and...
Reference: 10009365-480
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Cayman’s MTT Proliferation Assay provides an easy to use tool for studying the induction and inhibition of cell proliferation in any in vitro model. This kit will also allow investigators to screen drug candidates...
Reference: 10009582-2
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Cayman’s Glucose Assay provides a simple, reproducible, and sensitive tool for assaying glucose in plasma, serum, and urine. The glucose assay uses the glucose oxidase-peroxide reaction for the determination of...
Reference: 10009779-2
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The mechanism for the movement of cholesterol from intracellular sites to their ultimate cellular destination is an unresolved question of fundamental importance to cell biology and medicine. Thus, defining mechanisms...
Reference: 10009846-96
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CREB (cAMP-response-element-binding protein) is a transcription factor that binds to cAMP-responsive element (CRE) promoter sites to regulate the transcription of numerous genes involved in metabolic regulation,...
Reference: 10009926-96
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Cayman’s PC Assay provides a specific, sensitive, and convenient method for quantifying PC in plasma or serum. In this assay, PC-Specific PLD hydrolyzes PC to choline and phosphatidic acid. The newly formed choline is...
Reference: 10009928-96
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Sphingomyelin is an important lipid component of cell membranes and lipoproteins. Cayman’s SM Assay provides a specific, sensitive, and convenient method for quantifying SM in plasma or serum in a 96-well format with...
Reference: 10010199-480
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Cayman's WST-8 Cell Proliferation Assay provides a tool for studying induction and inhibition of cell proliferation in any in vitro model. The assay is based on the extracellular reduction of WST-8 by NADH produced in...
Reference: 10010199-96
€0.00 (tax incl.)
Cayman's WST-8 Cell Proliferation Assay provides a tool for studying induction and inhibition of cell proliferation in any in vitro model. The assay is based on the extracellular reduction of WST-8 by NADH produced in...
Reference: 10010200-480
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Cayman’s XTT Cell Proliferation Assay provides an easy to use tool for studying induction and inhibition of cell proliferation in any in vitro model. The assay is based on the extracellular reduction of XTT by NADH...
Reference: 10010200-96
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Cayman’s XTT Cell Proliferation Assay provides an easy to use tool for studying induction and inhibition of cell proliferation in any in vitro model. The assay is based on the extracellular reduction of XTT by NADH...
Reference: 10010231-1
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Cayman’s FABP4 Ligand Binding Assay provides a simple, reproducible, and sensitive tool for the identification of FABP4 ligands. The assay makes use of a detection reagent that exhibits increased fluorescence at 500...
Reference: 10010303-96
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The measurement of TG levels, in conjunction with other lipid assays, are useful in the diagnosis of primary and secondary hyperlipoproteinemia, dyslipidemia, and triglyceridemia. Cayman’s TG Assay Kit provides a...
Reference: 10010401-96
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The sirtuins represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs) that catalyze a reaction coupling lysine deacetylation to the formation of nicotinamide and...
Reference: 10010721-1
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Glutathione (GSH) is involved in maintenance of protein sulfhydryl reduction status. PSSG may modify the activity of a large number of cell proteins, including metabolic, structural, cytoskeletal, and signaling...
Reference: 10010755-96
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Glycerol is the backbone of triglycerides and an important intermediate in energy metabolism being involved in both oxidative and synthetic processes. The circulating levels of glycerol and free fatty acids are...
Reference: 10010854-96
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Three known isoforms of SREBP transcription factors have been characterized: SREBP-1a, SREBP-1c, and SREBP-2. SREBP-1c acts primarily to activate genes required for fatty acid synthesis, such as acetyl-CoA...
Reference: 10010895-96
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XO catalyzes the hydroxylation of hypoxanthine to xanthine and then further catalyzes the oxidation of xanthine to uric acid. When oxidizing NADH, XO generates superoxide, a powerful ROS. XO is found predominantly in...
Reference: 10010991-96
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Human SIRT1 is the homolog of yeast Sir2 and has been shown to regulate the activity of the p53 tumor suppressor and inhibit apoptosis. Cayman’s SIRT1 FRET-based Screening Assay provides a convenient...
Reference: 10011096-1
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Cell-Based Assay EGCG has been formulated and tested to work with Cayman’s Assay Kits. Detailed instructions for its use are contained in the respective Cayman Assay Kit booklet.
Reference: 10011125-1
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LDL uptake and its regulation are important therapeutic targets for atherosclerosis and related diseases. Cayman Chemical’s LDL Uptake Cell-Based Assay employs a preparation of human LDL conjugated to Dylight™ 550 as...
Reference: 10011563-96
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HDACs catalyze the hydrolytic removal of acetyl groups from histone lysine residues resulting in chromatin condensation and transcriptional repression of chromosomal DNA. Thus, HDAC inhibition allows the conformation...
Reference: 10011564-96
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Cayman’s HDAC1 Inhibitor Screening Assay provides a fast, fluorescence based method for screening HDAC1 inhibitors. The procedure requires only two easy steps, both performed in the same microplate. The fluorescent...
Reference: 10011566-96
€0.00 (tax incl.)
The sirtuins represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs) that catalyze a reaction coupling lysine deacetylation to the formation of nicotinamide and...
Reference: 10011671-96
€0.00 (tax incl.)
Small molecule inhibitors of sEH may hold promise as therapeutics for the treatment of hypertension and vascular inflammation. Cayman’s fluorescence-based sEH Inhibitor Screening Assay provides a convenient method for...
Reference: 10011725-1
€0.00 (tax incl.)
Cayman’s Glycerol Cell-Based Assay provides a convenient tool for studying triglycerides/fatty acid cycling and its regulation in adipocytes or hepatocytes. This kit will allow investigators to screen compounds...
Reference: 18534-100
€0.00 (tax incl.)
These tubes are specifically designed to be used for 1 ml blood samples which will be assayed both for 8-isoprostanes and prostaglandins. BHT sampling tubes may be useful for any lipid peroxidation and COX metabolites...
Reference: 18534-150
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These tubes are specifically designed to be used for 1 ml blood samples which will be assayed both for 8-isoprostanes and prostaglandins. BHT sampling tubes may be useful for any lipid peroxidation and COX metabolites...
Reference: 18534-35
€0.00 (tax incl.)
These tubes are specifically designed to be used for 1 ml blood samples which will be assayed both for 8-isoprostanes and prostaglandins. BHT sampling tubes may be useful for any lipid peroxidation and COX metabolites...
Reference: 23042-1
€0.00 (tax incl.)
Designed to allow the user to detect and quantitatively measure the amount of cyclic AMP (cAMP) present in cell based assay systems.
Reference: 24854-1
€0.00 (tax incl.)
Cayman's LAL Activity MaxSpec® Assay Kit includes the necessary reagents to quantify lysosomal acid lipase (LAL) activity in dried blood spots. The LAL Activity MaxSpec® Assay Substrate (P-PMHC) has been designed to...
Reference: 25659-96
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Present in nature in the form of iodide and iodate, iodine is a solid halogen at normal temperature. It is used in medicine, in the pharmaceutical and food industry. Food is the principal daily supply of iodide in...
Reference: 26404-96
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The Glutathione Fluorescent Assay Kit is designed to measure the amount of total glutathione (GSH+GSSG) in cells and tissue homogenates and the total amount (including GSSG and protein mixed disulfides with...
Reference: 28760-50
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For screening a variety of immuno-oncology associated compounds; contains more than 90 cancer and immunology-associated compounds as 10 mM stock solutions in DMSO; includes a variety of immuno-oncology target...
Reference: 31530-50
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For screening a variety of anti-inflammatory compounds; contains ~235 compounds in a 96-well Matrix™ tube rack format as 10 mM stock solutions in DMSO; includes a variety of compounds that inhibit pro-inflammatory...
Reference: 500001-480
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Cayman’s Lipid Droplets Fluorescence Assay Kit can be used to study regulators of lipid droplet biogenesis. The main advantage of this assay is that the green fluorescence of Nile Red is both very sensitive and...
Reference: 500290-1
€0.00 (tax incl.)
Cayman’s Phagocytosis Assay Kit (IgG FITC) employs latex beads coated with fluorescently-labeled rabbit IgG as a probe for the measurement of the phagocytic process in vitro. The engulfed fluorescent beads can be...
Reference: 560101-96
€0.00 (tax incl.)
The COX (ovine) Inhibitor Screening Assay directly measures PGF2α produced in the cyclooxygenase reaction. The prostanoid product is quantified via ELISA using a broadly specific antibody that binds to all the major...
Reference: 560131-96
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The COX (ovine/human) Inhibitor Screening Assay directly measures PGF2α produced by SnCl2 reduction of COX-derived PGH2. The prostanoid product is quantified via ELISA using a broadly specific antibody that binds to...
Reference: 600020-96
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The tumor suppressor protein p53 plays a crucial role in coordinating cellular responses to genotoxic stress and holds many important clinical implications in the treatment of cancer. Cayman’s p53 Transcription Factor...
Reference: 600050-480
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Reactive oxygen species, such as hydrogen peroxide (H2O2) and superoxide are generated by phagocytes and participate in damaging invading miccroorganisms or other biologic targets.(29448) Cayman's H2O2 Cell-Based...
Reference: 600050-96
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Reactive oxygen species, such as hydrogen peroxide (H2O2) and superoxide are generated by phagocytes and participate in damaging invading miccroorganisms or other biologic targets.(29448) Cayman's H2O2 Cell-Based...
Reference: 600090-480
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Mammalian sEH is a member of the α/β-hydrolase fold family of enzymes that catalyze the hydrolysis of exogenous and endogenous epoxides to vicinal diols. Endogenous substrates for sEH include EETs which exhibit...
Reference: 600120-1
€0.00 (tax incl.)
Cayman’s 7-AAD/CFSE Cell-Mediated Cytotoxicity Assay Kit employs CFSE to label target cells within the mixed cell population and 7-AAD to label dead cells. This kit provides an improvement over the traditional...
Reference: 600140-1
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Cayman’s Autophagy/Cytotoxicity Dual Staining provides a convenient tool for studying the regulation of autophagy and cytotoxicity at the cellular level. The kit employs MDC, an autofluorescent substance incorporated...
Reference: 600160-10
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Protein MetO is a reversible oxidative modification that occurs by exposure of protein(s) methionine residues to reactive oxygen species (ROS). Methionine oxidation can alter the function(s) of the modified proteins...
Reference: 600180-100
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Cayman's MC3R Reporter Assay consists of a 96-well plate coated with a transfection complex containing DNA constructs for MC3R and a cAMP response element regulated Secreted Alkaline Phosphatase (SEAP) reporter (MC3R...
Reference: 600190-100
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Cayman’s MC4R Reporter Assay consist of a 96-well plate coated with a transfection complex containing DNA constructs for MC4R and a cAMP response element regulated Secreted Alkaline Phosphatase (SEAP) reporter (MC4R...
Reference: 600240-100
€0.00 (tax incl.)
Cayman's OX1R Reporter Assay Kit consists of a 96-well plate coated with a transfection complex containing DNA constructs for OX1R, a recombinant G-protein, and a cAMP response element regulated Secreted Alkaline...
Reference: 600250-100
€0.00 (tax incl.)
Cayman's OX2R Reporter Assay Kit consists of a 96-well plate coated with both OX2R and Secreted Alkaline Phosphatase (SEAP) reporter constructs (OX2R Reverse Transfection Strip Plate). Cells grown on the transfection...
Reference: 600300-100
€0.00 (tax incl.)
One of the hallmarks of the early stages of apoptosis is the redistribution of membrane phospholipids such as phosphatidylserine and phosphatidylethanolamine from the inner to outer leaflet of the membrane bilayer...
Reference: 600320-96
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Reactive oxygen species (ROS) react with proteins, resulting in protein modification, such as protein sulfenylation through the reversible oxidation of cysteine residues. Redox-sensitive cysteine residues in proteins...
Reference: 600340-100
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The EP2 receptor is one of four GPCRs that mediate the actions of PGE2. The diverse effects of PGE2 acting via EP2 receptors point to the need to identify novel agonists and antagonists, both to further elucidate the...
Reference: 600350-100
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The EP4 receptor is one of four GPCRs that mediate the actions of prostaglandin E2 (PGE2). The diverse effects of PGE2 acting via EP4 receptors point to the need to identify novel agonists and antagonists, both to...
Reference: 600360-96
€0.00 (tax incl.)
Glutathione (GSH) is a low molecular-weight tripeptide thiol that serves as a primary cellular anti-oxidant and plays a fundamental role in the elimination of environmental toxins. During early apoptosis, cells may...
Reference: 600370-1
€0.00 (tax incl.)
Cayman's Multidrug Resistance Assay Kit provides a convenient tool for studying the modulation of cellular multidrug resistance (MDR) machinery. The kit employs calcein AM, a cell-permeable nonfluorescent dye, which...
Reference: 600410-1
€0.00 (tax incl.)
The EP4 receptor is one of four GPCRs that mediate the actions of prostaglandin E2 (PGE2). The diverse effects of PGE2 acting via EP4 receptors point to the need to identify novel agonists and antagonists, both to...
Reference: 600440-1
€0.00 (tax incl.)
Maintaining body cholesterol homeostasis is critical for normal physiological functions and is achieved by a highly regulated balance of de novo synthesis, dietary cholesterol absorption, biliary clearance, and...

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