Antibodies

Tau Rabbit pAb

Reference: A0002

€0.00 (tax incl.)

This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in...

TLR4 Rabbit pAb

Reference: A0007

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The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila...

PTEN Rabbit pAb

Reference: A0008

€0.00 (tax incl.)

This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains...

PARP1 Rabbit pAb

Reference: A0010

€0.00 (tax incl.)

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation...

Cytokeratin 4 (KRT4) Rabbit mAb

Reference: A0013

€0.00 (tax incl.)

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during...

Caspase-9 Rabbit pAb

Reference: A0019

€0.00 (tax incl.)

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive...

STAT1 Rabbit pAb

Reference: A0027

€0.00 (tax incl.)

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or...

Tyrosine Hydroxylase Rabbit pAb

Reference: A0028

€0.00 (tax incl.)

The protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic...

STIP1 Rabbit mAb

Reference: A0036

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STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to...

B-Raf Rabbit pAb

Reference: A0038

€0.00 (tax incl.)

This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division,...

MGMT Rabbit pAb

Reference: A0052

€0.00 (tax incl.)

Alkylating agents are potent carcinogens that can result in cell death, mutation and cancer. The protein encoded by this gene is a DNA repair protein that is involved in cellular defense against mutagenesis and...

Thioredoxin 1 (Trx1/TXN) Rabbit pAb

Reference: A0053

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The protein encoded by this gene acts as a homodimer and is involved in many redox reactions. The encoded protein is active in the reversible S-nitrosylation of cysteines in certain proteins, which is part of the...

PI3 Kinase p85 alpha Rabbit pAb

Reference: A0054

€0.00 (tax incl.)

Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This...

Prohibitin Rabbit pAb

Reference: A0056

€0.00 (tax incl.)

This gene is evolutionarily conserved, and its product is proposed to play a role in human cellular senescence and tumor suppression. Antiproliferative activity is reported to be localized to the 3' UTR, which is...

VEGFR1 Rabbit pAb

Reference: A0058

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This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven...

Caveolin-1 Rabbit pAb

Reference: A0059

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The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in...

CYP1A2 Rabbit pAb

Reference: A0062

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This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol,...

MMP14/MT1-MMP Rabbit mAb

Reference: A0067

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Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as...

BCR Rabbit pAb

Reference: A0068

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A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is...

Integrin beta 3 (ITGB3/CD61) Rabbit pAb

Reference: A0076

€0.00 (tax incl.)

The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in...

FGF1 Rabbit pAb

Reference: A0079

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The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological...

FGFR1 Rabbit pAb

Reference: A0082

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The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ...

RANBP3 Rabbit mAb

Reference: A0092

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This gene encodes a protein with a RanBD1 domain that is found in both the nucleus and cytoplasm. This protein plays a role in nuclear export as part of a heteromeric complex. Alternate transcriptional splice...

Perforin Rabbit pAb

Reference: A0093

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The protein encoded by this gene has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of...

[KO Validated] CDK2 Rabbit mAb

Reference: A0094

€0.00 (tax incl.)

This gene encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. The encoded protein is the catalytic subunit of the cyclin-dependent protein kinase complex, which...

CAST Rabbit pAb

Reference: A0097

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The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is...

SERCA2/ATP2A2 Rabbit pAb

Reference: A0098

€0.00 (tax incl.)

This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the...

eEF2 Rabbit pAb

Reference: A0099

€0.00 (tax incl.)

This gene encodes a member of the GTP-binding translation elongation factor family. This protein is an essential factor for protein synthesis. It promotes the GTP-dependent translocation of the nascent protein chain...

FOXO3A Rabbit pAb

Reference: A0102

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This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for...

CDK6 Rabbit mAb

Reference: A0106

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The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces...

MSP/MST1 Rabbit mAb

Reference: A0109

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The protein encoded by this gene contains four kringle domains and a serine protease domain, similar to that found in hepatic growth factor. Despite the presence of the serine protease domain, the encoded protein may...

GluR2/GRIA2 Rabbit pAb

Reference: A0111

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Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of...

CCR7 Rabbit mAb

Reference: A0121

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The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on...

SHIP1 Rabbit pAb

Reference: A0122

€0.00 (tax incl.)

This gene is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and encodes a protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains....

Cytokeratin 17 (KRT17) Rabbit pAb

Reference: A0123

€0.00 (tax incl.)

This gene encodes the type I intermediate filament chain keratin 17, expressed in nail bed, hair follicle, sebaceous glands, and other epidermal appendages. Mutations in this gene lead to Jackson-Lawler type...

NCSTN Rabbit pAb

Reference: A0128

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This gene encodes a type I transmembrane glycoprotein that is an integral component of the multimeric gamma-secretase complex. The encoded protein cleaves integral membrane proteins, including Notch receptors and...

LRP5 Rabbit pAb

Reference: A0130

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This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein...

PSD95 Rabbit mAb

Reference: A0131

€0.00 (tax incl.)

This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with another MAGUK protein, DLG2, and is recruited into NMDA receptor and potassium channel clusters. These...

DUSP6 Rabbit mAb

Reference: A0133

€0.00 (tax incl.)

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and...

BCL2A1 Rabbit pAb

Reference: A0134

€0.00 (tax incl.)

This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities...

TRMT2A/HTF9C Rabbit mAb

Reference: A0136

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The protein encoded by this gene is of unknown function. However, it is orthologous to the mouse Trmt2a gene and contains an RNA methyltransferase domain. Expression of this gene varies during the cell cycle, with...

SLC9A3R1 Rabbit pAb

Reference: A0146

€0.00 (tax incl.)

This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled...

PGP9.5/UCHL1 Rabbit pAb

Reference: A0148

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The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the...

Doublecortin Rabbit pAb

Reference: A0149

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This gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing cortex, cortical...

TRAF1 Rabbit pAb

Reference: A0150

€0.00 (tax incl.)

The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR...

RACK1 Rabbit pAb

Reference: A0151

€0.00 (tax incl.)

Scaffolding protein involved in the recruitment, assembly and/or regulation of a variety of signaling molecules. Interacts with a wide variety of proteins and plays a role in many cellular processes. Component of the...

Cardiac Troponin I (TNNI3) Rabbit pAb

Reference: A0152

€0.00 (tax incl.)

Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin...

ALDH1A1 Rabbit mAb

Reference: A0157

€0.00 (tax incl.)

The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major...

IRF7 Rabbit pAb

Reference: A0159

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IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular...

Alpha Fodrin Rabbit pAb

Reference: A0160

€0.00 (tax incl.)

Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and...

Ubiquitin Rabbit pAb

Reference: A0162

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This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of...

VASP Rabbit pAb

Reference: A0166

€0.00 (tax incl.)

Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets...

MYH9 Rabbit pAb

Reference: A0173

€0.00 (tax incl.)

This gene encodes a conventional non-muscle myosin; this protein should not be confused with the unconventional myosin-9a or 9b (MYO9A or MYO9B). The encoded protein is a myosin IIA heavy chain that contains an IQ...

FADS1 Rabbit mAb

Reference: A0178

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The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of...

HDAC4 Rabbit pAb

Reference: A0179

€0.00 (tax incl.)

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to...

ARAF Rabbit pAb

Reference: A0180

€0.00 (tax incl.)

This proto-oncogene belongs to the RAF subfamily of the Ser/Thr protein kinase family, and maybe involved in cell growth and development. Alternatively spliced transcript variants encoding different isoforms have been...

Rad50 Rabbit pAb

Reference: A0182

€0.00 (tax incl.)

The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds...

Tec Rabbit pAb

Reference: A0189

€0.00 (tax incl.)

The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of...

β-arrestin1 Rabbit pAb

Reference: A0190

€0.00 (tax incl.)

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as...

Bcl10 Rabbit pAb

Reference: A0191

€0.00 (tax incl.)

This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce...

CaMKII Rabbit mAb

Reference: A0198

€0.00 (tax incl.)

The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at...

Alpha-Fetoprotein (AFP) Rabbit pAb

Reference: A0200

€0.00 (tax incl.)

This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However,...

ATF6 Rabbit pAb

Reference: A0202

€0.00 (tax incl.)

This gene encodes a transcription factor that activates target genes for the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Although it is a transcription factor, this protein is unusual in...

ATG5 Rabbit pAb

Reference: A0203

€0.00 (tax incl.)

The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular...

Bak Rabbit pAb

Reference: A0204

€0.00 (tax incl.)

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular...

APP Rabbit pAb

Reference: A0206

€0.00 (tax incl.)

This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase...

[KO Validated] Bax Rabbit pAb

Reference: A0207

€0.00 (tax incl.)

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular...

Bcl-2 Rabbit pAb

Reference: A0208

€0.00 (tax incl.)

This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig...

Bcl-XL Rabbit pAb

Reference: A0209

€0.00 (tax incl.)

The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular...

Bid Rabbit pAb

Reference: A0210

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This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage...

Bmi1 Rabbit pAb

Reference: A0211

€0.00 (tax incl.)

This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory...

BRCA1 Rabbit pAb

Reference: A0212

€0.00 (tax incl.)

This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and...

BVES Rabbit pAb

Reference: A0213

€0.00 (tax incl.)

This gene encodes a member of the POP family of proteins containing three putative transmembrane domains. This gene is expressed in cardiac and skeletal muscle and may play an important role in development of these...

Caspase-3 Rabbit pAb

Reference: A0214

€0.00 (tax incl.)

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as...

Caspase-8 Rabbit pAb

Reference: A0215

€0.00 (tax incl.)

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive...

Caspase-10 Rabbit pAb

Reference: A0216

€0.00 (tax incl.)

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as...

Caspase-12 Rabbit pAb

Reference: A0217

€0.00 (tax incl.)

Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory...

CD40 Rabbit pAb

Reference: A0218

€0.00 (tax incl.)

This gene is a member of the TNF-receptor superfamily. The encoded protein is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory...

CD133 Rabbit pAb

Reference: A0219

€0.00 (tax incl.)

This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties...

CDK1 Rabbit pAb

Reference: A0220

€0.00 (tax incl.)

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is...

Raf1 Rabbit pAb

Reference: A0223

€0.00 (tax incl.)

This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds...

C-Reactive Protein (CRP) Rabbit pAb

Reference: A0224

€0.00 (tax incl.)

The protein encoded by this gene belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to...

[KO Validated] Cytochrome C Rabbit pAb

Reference: A0225

€0.00 (tax incl.)

This gene encodes a small heme protein that functions as a central component of the electron transport chain in mitochondria. The encoded protein associates with the inner membrane of the mitochondrion where it...

DOK4 Rabbit pAb

Reference: A0226

€0.00 (tax incl.)

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays...

p38 MAPK Rabbit pAb

Reference: A0227

€0.00 (tax incl.)

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as...

[KO Validated] ERK1 Rabbit pAb

Reference: A0228

€0.00 (tax incl.)

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes...

[KO Validated] ERK2 Rabbit pAb

Reference: A0229

€0.00 (tax incl.)

This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide...

SIRT1 Rabbit pAb

Reference: A0230

€0.00 (tax incl.)

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions...

BMP2 Rabbit pAb

Reference: A0231

€0.00 (tax incl.)

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD...

FABP4 Rabbit pAb

Reference: A0232

€0.00 (tax incl.)

FABP4 encodes the fatty acid binding protein found in adipocytes. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic...

Fas Rabbit pAb

Reference: A0233

€0.00 (tax incl.)

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death,...

FasLG Rabbit pAb

Reference: A0234

€0.00 (tax incl.)

This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is...

FGF2 Rabbit pAb

Reference: A0235

€0.00 (tax incl.)

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in...

c-Fos Rabbit pAb

Reference: A0236

€0.00 (tax incl.)

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex...

GFAP Rabbit pAb

Reference: A0237

€0.00 (tax incl.)

This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause...

[KO Validated] HDAC1 Rabbit pAb

Reference: A0238

€0.00 (tax incl.)

Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone...

BiP/GRP78 Rabbit pAb

Reference: A0241

€0.00 (tax incl.)

The protein encoded by this gene is a member of the heat shock protein 70 (HSP70) family. It is localized in the lumen of the endoplasmic reticulum (ER), and is involved in the folding and assembly of proteins in the...

IFN gamma Rabbit pAb

Reference: A0242

€0.00 (tax incl.)

This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that...

[KO Validated] IGF1R Rabbit pAb

Reference: A0243

€0.00 (tax incl.)

This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor...

IRS1 Rabbit pAb

Reference: A0245

€0.00 (tax incl.)

This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.

Category: Antibodies

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