Epigenetics is a study of the heritable gene expression changes that do not involve alternations in DNA sequence. Prefix epi- signifies “on top of” or “in addition to”, hence epi-genetic is understood as something on top of genetics that changes the expression of the genes. Read More
The precision and accuracy of even the best calibrated pipette can be wiped out if you choose the wrong kind of tips. Depending on the experiment you are doing, the wrong kind of tips can also make your pipette a source of contamination, lead to waste of precious samples or reagents—or even cause you physical harm in the form of repetitive stress injury (RSI). There are so many different kinds of tips to choose from. How do you know which is the best for your pipette and situation? Never fear, that’s what we are here for.
All immunostaining and immunoassay applications depend on the use of sensitive and highly specific antibodies, yet despite cross-reactivity, batch-to-batch variability, and the use of antibodies in untested applications have all been blamed for causing potentially devastating effects on research.
AdipoGen Life Sciences AdipoGen Life Sciences (AdipoGen) is a research company developing proteins, biochemicals, antibodies and ELISA Kits. To promote the advancement of non-animal alternative approaches (3Rs), AdipoGen implemented the antibody phage display technology in-house to develop monoclonal antibodies without the use of animals.
This workshop intends to provide a firm understanding of the principles and applications of Flow Cytometry, combining the theoretical and practical sessions. Applicants may register in basic theoretical training modules only, or select the complete training including theoretical and practical sessions. Read More
Although exosomes were discovered over five decades ago, interest among the scientific community didn’t pique until much later. Specifically, in the last ten years, the number of annual publications about exosomes have almost increased by tenfold (from 1,570 published papers in 2007 to 14,000 in 2017). But what exactly are exosomes and what justifies the frenzy?
The genetic code is the footprint of an organism encoded in a stable molecule: deoxyribonucleic acid. With the CRISPR/Cas9 method, editing the genetic information has become much more easy. This wonderful methodology will be very useful for basic scientists, as well as for translational researchers.
The sensitive nature of PCR allows scientists to extract and amplify useful DNA profiles. However, this high level of sensitivity can also create problems because the wrong template can be amplified. In this blog entry, we are going to explore some tips to have in mind to include in our protocol.
Cancer is one of the major health problems. Although traditional therapies have been effective in cancer treatment, they often have adverse side effects due to their nonspecific action on both normal and tumor cells. Therefore, targeted treatment strategies using small molecule inhibitors are being extensively studied. These compounds are usually ≤500Da size and are often administered orally. In principle, small molecule compounds can be developed to target any portion of a molecule, regardless of the target’s cellular location. In this blog entry, we provide a summary of the small molecule inhibitors (SMIs) used in the cancer therapy.
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