Biología Molecular, Epigenetica, Epigenetics, Molecular Biology
Improving ChIP assays protocol: understanding chromatin and epigenetics
Epigenetics field has undergone a “boom” in recent years due to new cutting edge technologies. It is focused on changes produced in the DNA and histones. How? Modifying chromatin structure whilst preventing any modifications from happening at the nucleotide sequence level, but producing changes at the level of gene expression. There are several modifications occurring to histones: methylation, acetylation, ADP-ribosilation, ubiquitination and phosphorylation.
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