Primary antibodies (3)

Bax Polyclonal Antibody

Reference: GRP202

€0.00 (tax incl.)

Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes...

Bax Polyclonal Antibody

Reference: GRP203

€0.00 (tax incl.)

Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes...

PI3 kinase p85 alpha subunit Antibody

Reference: GRP204

€0.00 (tax incl.)

Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p11 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated...

HSP90 beta Polyclonal Antibody

Reference: GRP205

€0.00 (tax incl.)

Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional...

Tau protein Polyclonal Antibody

Reference: GRP206

€0.00 (tax incl.)

Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane...

p75 NGF Receptor Polyclonal Antibody

Reference: GRP207

€0.00 (tax incl.)

Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the...

BACE1 Polyclonal Antibody

Reference: GRP208

€0.00 (tax incl.)

Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and...

Neurokinin B receptor Antibody

Reference: GRP209

€0.00 (tax incl.)

This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this...

Caspase-1 P10 Polyclonal Antibody

Reference: GRP210

€0.00 (tax incl.)

Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates...

Estrogen Receptor alpha + beta Antibody

Reference: GRP211

€0.00 (tax incl.)

The estrogen receptor (ER) is a 66 kDa protein that mediates the actions of estrogens in estrogen responsive tissues. It is a member of a large superfamily of nuclear hormone receptors that function as ligand...

TrkB Polyclonal Antibody

Reference: GRP212

€0.00 (tax incl.)

Receptor tyrosine kinase involved in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival, proliferation, migration, differentiation, and synapse...

RAGE Polyclonal Antibody

Reference: GRP213

€0.00 (tax incl.)

Mediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins which accumulate in vascular tissue in aging and at an accelerated rate in diabetes. Acts as a...

PDGF B Polyclonal Antibody

Reference: GRP214

€0.00 (tax incl.)

Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal...

HSP60 Polyclonal Antibody

Reference: GRP215

€0.00 (tax incl.)

Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded...

TrkA Polyclonal Antibody

Reference: GRP216

€0.00 (tax incl.)

Receptor tyrosine kinase involved in the development and the maturation of the central and peripheral nervous systems through regulation of proliferation, differentiation and survival of sympathetic and nervous...

GRP94 Polyclonal Antibody

Reference: GRP217

€0.00 (tax incl.)

Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors (By similarity). Functions in endoplasmic...

PDGF A Polyclonal Antibody

Reference: GRP218

€0.00 (tax incl.)

Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal...

VPAC2R Polyclonal Antibody

Reference: GRP219

€0.00 (tax incl.)

This is a receptor for VIP as well as PACAP-38 and -27, the activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Can be coupled to phospholipase C.

GFAP Polyclonal Antibody

Reference: GRP220

€0.00 (tax incl.)

GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.

Tubulin-beta Polyclonal Antibody

Reference: GRP221

€0.00 (tax incl.)

Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.

Fas Ligand Polyclonal Antibody

Reference: GRP222

€0.00 (tax incl.)

Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have...

bFGF Polyclonal Antibody

Reference: GRP223

€0.00 (tax incl.)

Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro (By similarity).

TERT Polyclonal Antibody

Reference: GRP224

€0.00 (tax incl.)

Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells....

HSP70 1A/1B Polyclonal Antibody

Reference: GRP225

€0.00 (tax incl.)

In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones...

VEGF Polyclonal Antibody

Reference: GRP226

€0.00 (tax incl.)

Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels....

MTLC Polyclonal Antibody

Reference: GRP227

€0.00 (tax incl.)

May regulate certain MYC target genes, MYC seems to be a direct upstream transcriptional activator. Does not seem to significantly affect growth cell capacity. Overexpression seems to mediate many of the known...

Myelin Protein Zero Polyclonal Antibody

Reference: GRP228

€0.00 (tax incl.)

Creation of an extracellular membrane face which guides the wrapping process and ultimately compacts adjacent lamellae.

Histone H3 Polyclonal Antibody

Reference: GRP229

€0.00 (tax incl.)

Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently...

ZCWCC1 Polyclonal Antibody

Reference: GRP230

€0.00 (tax incl.)

Exhibits a cytosolic function in lipogenesis, adipogenic differentiation, and lipid homeostasis by increasing the activity of ACLY, possibly preventing its dephosphorylation. May act as a transcriptional repressor....

MBP Polyclonal Antibody

Reference: GRP231

€0.00 (tax incl.)

Oligodendrocyte Marker The classic group of Myelin basic protein (MBP) isoforms (isoforms 4 to 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its...

GLUT4 Polyclonal Antibody

Reference: GRP232

€0.00 (tax incl.)

GLUT4 is the facilitated glucose transporter expressed exclusively in adipocytes and muscle cells, and is also known as the "insulin-responsive" glucose transporter. GLUT4 translocates from an ill-defined...

ARC/Arg3.1 Polyclonal Antibody

Reference: GRP233

€0.00 (tax incl.)

Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA...

MMP9 Polyclonal Antibody

Reference: GRP234

€0.00 (tax incl.)

May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V...

Leptin Polyclonal Antibody

Reference: GRP235

€0.00 (tax incl.)

May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy...

MMP2 Polyclonal Antibody

Reference: GRP236

€0.00 (tax incl.)

Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as...

MMP-3 Polyclonal Antibody

Reference: GRP237

€0.00 (tax incl.)

Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase.

TIMP-1 Polyclonal Antibody

Reference: GRP238

€0.00 (tax incl.)

Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on...

MMP-7 Polyclonal Antibody

Reference: GRP239

€0.00 (tax incl.)

Matrix metalloproteinase-7 (MMP-7) also known as matrilysin and PUMP (EC 3.4.24.23) cleaves a number of substrates including collagen types IV and X, elastin, fibronectin, gelatin, laminin and proteoglycans. MMP-7 is...

OPG Polyclonal Antibody

Reference: GRP240

€0.00 (tax incl.)

Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend...

ACE Polyclonal Antibody

Reference: GRP241

€0.00 (tax incl.)

Angiotensin Converting enzyme is involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide...

NIS Polyclonal Antibody

Reference: GRP242

€0.00 (tax incl.)

catalyzes Na+/I- symporter activity plays a role in iodide transport and thyroid hormone generation.Human Sodium Iodide Symporter (hNIS) is responsible for iodide concentrating ability within thyroid follicular cells....

TSHR Polyclonal Antibody

Reference: GRP243

€0.00 (tax incl.)

Receptor for thyrothropin. Plays a central role in controlling thyroid cell metabolism. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Also acts as a receptor for...

NFKB p65 Polyclonal Antibody

Reference: GRP244

€0.00 (tax incl.)

NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological...

CD31 Polyclonal Antibody

Reference: GRP245

€0.00 (tax incl.)

Induces susceptibility to atherosclerosis (By similarity). Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-69 plays a critical role in...

Adiponectin Polyclonal Antibody

Reference: GRP246

€0.00 (tax incl.)

Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in...

IFN gamma Polyclonal Antibody

Reference: GRP247

€0.00 (tax incl.)

Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has...

IFN gamma Polyclonal Antibody

Reference: GRP248

€0.00 (tax incl.)

Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has...

EphA2 Polyclonal Antibody

Reference: GRP249

€0.00 (tax incl.)

Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway...

Dnmt3a Polyclonal Antibody

Reference: GRP250

€0.00 (tax incl.)

Required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a...

ADRB1 Polyclonal Antibody

Reference: GRP251

€0.00 (tax incl.)

Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity....

JNK1 + 3 Polyclonal Antibody

Reference: GRP252

€0.00 (tax incl.)

JNK1(MAPK8) is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation,...

FADD Polyclonal Antibody

Reference: GRP253

€0.00 (tax incl.)

Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8...

RAR Beta Polyclonal Antibody

Reference: GRP254

€0.00 (tax incl.)

Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various...

ATF3 Polyclonal Antibody

Reference: GRP255

€0.00 (tax incl.)

This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress...

CD44 Polyclonal Antibody

Reference: GRP256

€0.00 (tax incl.)

Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix...

SOX2 Polyclonal Antibody

Reference: GRP257

€0.00 (tax incl.)

Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP26. Critical for early...

CD10 Polyclonal Antibody

Reference: GRP258

€0.00 (tax incl.)

Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 3 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a...

PPAR gamma Polyclonal Antibody

Reference: GRP259

€0.00 (tax incl.)

The PPAR gamma antibody mainly is exist in the white fat organization, the fat for the PPAR gamma is born, blood sugar stability, the disease respond, the artery gruel kind hardens to rise the important function with...

TFF3 Polyclonal Antibody

Reference: GRP260

€0.00 (tax incl.)

Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen).

CaMK2 Polyclonal Antibody

Reference: GRP261

€0.00 (tax incl.)

CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may...

SCF Polyclonal Antibody

Reference: GRP262

€0.00 (tax incl.)

Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development,...

Endostatin Polyclonal Antibody

Reference: GRP263

€0.00 (tax incl.)

COLA18A probably plays a major role in determining the retinal structure as well as in the closure of the neural tube. Endostatin potently inhibits endothelial cell proliferation and angiogenesis. May inhibit...

IL-13 Polyclonal Antibody

Reference: GRP264

€0.00 (tax incl.)

Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses (By similarity).

Smad7 Polyclonal Antibody

Reference: GRP265

€0.00 (tax incl.)

Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit TGF-beta (Transforming growth factor) and activin signaling by associating with their...

Integrin alpha 5 Polyclonal Antibody

Reference: GRP266

€0.00 (tax incl.)

Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance...

CDK6 Polyclonal Antibody

Reference: GRP267

€0.00 (tax incl.)

Serine/threonine-protein kinase involved in the control of the cell cycle and differentiation; promotes G1/S transition. Phosphorylates pRB/RB1 and NPM1. Interacts with D-type G1 cyclins during interphase at G1 to...

Cyclin B1 Polyclonal Antibody

Reference: GRP268

€0.00 (tax incl.)

The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a...

MMP-13 Polyclonal Antibody

Reference: GRP269

€0.00 (tax incl.)

Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the...

IL2RA Polyclonal Antibody

Reference: GRP270

€0.00 (tax incl.)

The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity...

WWOX Polyclonal Antibody

Reference: GRP271

€0.00 (tax incl.)

Putative oxidoreductase. Acts as a tumor suppressor and plays a role in apoptosis. Required for normal bone development (By similarity). May function synergistically with p53/TP53 to control genotoxic stress-induced...

E2F1 Polyclonal Antibody

Reference: GRP272

€0.00 (tax incl.)

Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle...

ICAM1 Polyclonal Antibody

Reference: GRP273

€0.00 (tax incl.)

ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through...

OAT-3 Polyclonal Antibody

Reference: GRP274

€0.00 (tax incl.)

Plays an important role in the excretion/detoxification of endogenous and exogenous organic anions, especially from the brain and kidney. Involved in the transport basolateral of steviol, fexofenadine. Transports...

Adiponectin Receptor 1 Antibody

Reference: GRP275

€0.00 (tax incl.)

Receptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty...

Survivin Polyclonal Antibody

Reference: GRP276

€0.00 (tax incl.)

Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis. Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation...

ZNF300 Polyclonal Antibody

Reference: GRP277

€0.00 (tax incl.)

ZNF300 contains C2H2 (or Kruppel)-type zinc finger motifs that tetrahedrally coordinate zinc ions and form a protein structure that can bind DNA and regulate transcription (Gou et al.,2004 [PubMed 14746915]). ZNF300...

CDK4 Polyclonal Antibody

Reference: GRP278

€0.00 (tax incl.)

Ser/Thr-kinase component of cyclin D-CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and regulate the cell-cycle during G(1)/S transition....

Aquaporin 4 Polyclonal Antibody

Reference: GRP279

€0.00 (tax incl.)

Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system.

P38 MAPK Polyclonal Antibody

Reference: GRP280

€0.00 (tax incl.)

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as...

TGF Beta R1 Polyclonal Antibody

Reference: GRP281

€0.00 (tax incl.)

Transmembrane serine/threonine kinase forming with the TGF-beta type II serine/threonine kinase receptor, TGFBR2, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1,...

CD34 Polyclonal Antibody

Reference: GRP282

€0.00 (tax incl.)

Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment...

CD4 Polyclonal Antibody

Reference: GRP283

€0.00 (tax incl.)

Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a...

CD68 Polyclonal Antibody

Reference: GRP284

€0.00 (tax incl.)

Could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. Binds to tissue- and organ-specific lectins or...

Connexin 43 Polyclonal Antibody

Reference: GRP285

€0.00 (tax incl.)

Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from...

HMGB1 Polyclonal Antibody

Reference: GRP286

€0.00 (tax incl.)

DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by...

Fibronectin Polyclonal Antibody

Reference: GRP287

€0.00 (tax incl.)

Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of...

SYVN1 Polyclonal Antibody

Reference: GRP288

€0.00 (tax incl.)

Acts as an E3 ubiquitin-protein ligase which accepts ubiquitin specifically from endoplasmic reticulum-associated UBC7 E2 ligase and transfers it to substrates, promoting their degradation. Component of the...

IL-10 Polyclonal Antibody

Reference: GRP289

€0.00 (tax incl.)

Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells.

Ceramide glucosyltransferase Antibody

Reference: GRP290

€0.00 (tax incl.)

Catalyzes the first glycosylation step in glycosphingolipid biosynthesis, the transfer of glucose to ceramide. May also serve as a "flippase".

Collagen 2 Polyclonal Antibody

Reference: GRP291

€0.00 (tax incl.)

Type II collagen is specific for cartilaginous tissues. It is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces.

p63 Polyclonal Antibody

Reference: GRP292

€0.00 (tax incl.)

Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform...

HSP27 Polyclonal Antibody

Reference: GRP293

€0.00 (tax incl.)

Heat Shock Protein 27 (HSP27) is a 27 kDa member of a family of proteins whose expression and function are stimulated by heat shock and other stress stimuli. A major function of these proteins is to serve as...

Cyclooxygenase 2 Polyclonal Antibody

Reference: GRP294

€0.00 (tax incl.)

Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in...

CD56 Polyclonal Antibody

Reference: GRP295

€0.00 (tax incl.)

This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.

HIF-1 Alpha Polyclonal Antibody

Reference: GRP296

€0.00 (tax incl.)

Functions as a master transcriptional regulator of the adaptive response to hypoxia. Under hypoxic conditions, activates the transcription of over 4 genes, including erythropoietin, glucose transporters, glycolytic...

Livin Polyclonal Antibody

Reference: GRP297

€0.00 (tax incl.)

Apoptotic regulator capable of exerting proapoptotic and anti-apoptotic activities and plays crucial roles in apoptosis, cell proliferation, and cell cycle control. Its anti-apoptotic activity is mediated through the...

CDKN1B Polyclonal Antibody

Reference: GRP298

€0.00 (tax incl.)

Important regulator of cell cycle progression. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly,...

CTGF Polyclonal Antibody

Reference: GRP299

€0.00 (tax incl.)

Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell...

PCNA Polyclonal Antibody

Reference: GRP300

€0.00 (tax incl.)

Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust...

Vimentin Polyclonal Antibody

Reference: GRP301

€0.00 (tax incl.)

Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or...

Category: Primary antibodies

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