IQ Products

IQ Products is an international developer, manufacturer and supplier of a wide range of antibody-based diagnostic products and is headquartered in the Netherlands. It was founded in cooperation with the leading University of Groningen, in the north of The Netherlands in 1987. Extensive know-how resulted in the development of innovative kits in niche areas and currently focuses on Women’s Health and pregnancy related disorders in particular.

Flow cytometry is one of their specialties and very suitable for detecting rare cells in large populations. Over the years IQ Products has developed different diagnostic assays to detect these rare cell populations primarily based on high quality antibodies, for instance the Fetal Cell Count™ Kit. Currently the Research & Development of the company are focussed on pregnancy related disorders like pre-eclampsia (PE) and intra-uterine growth restriction (IUGR).

Fetomaternal Hemorrhage (FMH)

Fetomaternal Hemorrhage (FMH), the transplacental passage of fetal red blood cells (fRBCs) into the maternal circulation, can be caused by complications in abdominal trauma, suspected placental injury or a cesarean section. Severe FMH may lead to intra-uterine death. In case of antigen (RhD) incompatibility between mother and child, FMH may result in Hemolytic Disease of the Newborn. In this case, correct enumeration of the amount of fRBCs is essential for (prophylactic) anti-D therapy.

IQ Products detection kits:

• Fetal Cell Count™ Kit: Complete assay for routine diagnosis of Fetomaternal Hemorrhage using anti-HbF and anti-CA.
• FMH QuikQuant™: Rapid assay for Fetomaternal Hemorrhage Quantification,
• FETALtrol™ 2: Tri-level stabilized blood controls with known human fetal erythrocytes content in human adult blood.

If you want a quote or more information, do not hesitate to contact us:

Figure 1. Dotplots illustrating typical data obtained with the Fetal Cell Count™ kit: A) FSC/SSC plot to identify the red blood cell population. B) FSC-A/FSC-W plot to exclude doublets. C) CA-FITC/HbF plot to identify fetal red blood cells (UL).